Northeastern University

Psilocybin as a treatment for repetitive mild head injury: evidence from neuroradiology and molecular biology

Repetitive mild head injuries incurred while playing organized sports, during car accidents and falls, or in active military service are a major health problem. These head injuries induce cognitive, motor, and behavioral deficits that can last for months and even years with an in...

Air Quality in Cities: What Do Sparse Sensor Networks Miss?

Abstract Stationary air quality networks are increasingly being used to refine urban air pollution exposure assessments and inform local government decision-making, yet to date, a comprehensive assessment of the extent to which such measurements provide sufficient spatial resolut...

Repeatability and behavioral relationships of acuity, contrast sensitivity, form, and motion perception measurements using a novel tablet-based vision test tool

Abstract Visual function tests are essential in basic and clinical vision research but are typically restricted to a limited range of visual functions and provide coarse diagnostic resolution. The response-adaptive Angular Indication Measurement (AIM) and Foraging Interactive D-p...

An Exploratory Investigation of Definition, Formation, and Maintenance in Roster Sexual Relationships

Casual sexual relationship research has traditionally focused on dyadic relationship forms, including hookups, friends-with-benefits relationships, and situationships. Missing from these frameworks is a relationship structure increasingly recognized by adults themselves: the rost...

Truly mobile sub-terahertz communications beyond 6G via just-in-time IMU-assisted beam management

Abstract Sub-Terahertz (sub-THz) communication is a candidate for beyond-sixth-generation (beyond 6G) networks, promising Terabit-per-second rates at microsecond latencies. However, the highly directional beams required to overcome severe path loss make beam alignment under mobil...

Impact pathway: beyond automation and augmentation – a relational ontology of AI in operations and supply chain management

Purpose As companies deploy increasingly agentic forms of AI to coordinate and manage workflows, AI can no longer be understood as a discrete technological tool added to existing operations and supply chains. We propose a relational ontology as an alternative theoretical foundati...

Sequence-defined Digital Bottlebrush Polymers for Programmable Oligonucleotide Delivery

Oligonucleotide therapeutics hold transformative potential, yet their clinical translation is hindered by delivery barriers, including rapid renal/hepatic clearance and poor organ specificity. Bottlebrush polymers conjugates have emerged as a promising vector to address these lim...

A conceptual framework for epistemic boundary definition between project management and data science

Purpose Project management and data science are increasingly intersecting in project environments, yet no established theory explains the organizational friction that arises when these two professional domains must collaborate on shared project decisions. Current literature frame...

Tracking regulatory convergence in Asia-Pacific Economic Cooperation (APEC): progress and gaps in key performance indicators

Abstract Purpose To assess progress in regulatory convergence among APEC economies using updated Key Performance Indicators (KPI) and to identify opportunities for strengthening reliance and work sharing, while informing future Phase 2 KPI development. Our work describes the adop...

Traces of Criminal Records: Digital Reputation and Information Concealment Policy

ABSTRACT In the United States, a robust data ecosystem aggregates and shares public records about people that may ultimately appear in Internet search results for a person's name. These records can include stigmatizing information and operate outside public policy efforts to conc...

Mass univariate aggregation methods for machine learning in neuroscience

Machine learning is a ubiquitous part of the modern neuroimaging toolkit, particularly for research aimed towards precision medicine goals of improving individual-level diagnosis and treatment. However, the high dimensionality of neuroimaging data poses significant challenges for...

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

ABSTRACT Cardiovascular disease (CVD) continues to be a significant contributor to premature mortality and the financial burden of healthcare. Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs) are increasingly utilized to investigate patient‐specific genetic...

Design and evaluation of curcumin-loaded sodium alginate/lignosulfonate beads for controlled pesticide release in sustainable agricultural applications

Biopesticides often face limitations in agriculture due to poor solubility, photodegradation, and environmental loss. This study developed calcium-crosslinked sodium alginate–lignosulfonate beads for sustained curcumin delivery and evaluated the effect of crosslinking duration. S...

An enantioselective covalent inhibitor of BAX confers cytoprotection in vivo

No therapies directly block apoptosis in tissue injury or the many diseases driven by cell loss. The BCL-2 family protein BAX is a central mediator of this pathway and C126 resides within a key regulatory region where physiologic or pharmacologic ligands can activate or inhibit i...

Lê Modules and Hypersurfaces with One-dimensional Singular Sets

Abstract By using our previous results on Lê modules and an upper-bound on the betti numbers which we proved with Lê, we investigate the cohomology of Milnor fibers and the internal local systems given by the vanishing cycles of hypersurfaces with one-dimensional singular sets an...

Physical and mental health conditions in men who have sex with men: a global umbrella review of meta-analyses

Men who have sex with men (MSM) face a disproportionate burden of health problems. Prior syntheses among MSM have not comprehensively addressed key areas such as non-communicable diseases, mental health, and comorbidities. This umbrella review aimed to synthesize and evaluate met...

“Made with AI” but why? How consumers interpret beneficiary-framed AI disclosures in advertising

Abstract As generative AI becomes more prevalent in advertising, firms increasingly face requirements to disclose AI involvement. Although prior research shows that such disclosures may generate negative consumer responses, it remains unclear whether explanatory disclosures can m...

The real estate turn in the slum: India’s urban land monetization in comparative perspective

This article contributes to scholarship on Asia’s “real estate turn” through a comparison of in situ “slum redevelopment” programs underway in Delhi and Mumbai that reveals the institutional underpinnings and character of state involvement in each city. Comparative research on st...

AMOC Weakening Controls δ 18 O but Not Rainfall in North China During Deglacial Abrupt Events

Abstract East Asian Summer Monsoon (EASM) varied at orbital and millennial timescales during the Last Deglaciation (∼20–11 ka). The uniform δ 18 O response in East China is often linked to EASM circulation that drives a precipitation dipole in North and South China on orbital sca...

Exercise addiction, social interaction, and the moderating effects of disordered eating among adults aged 18–35

Physical exercise is beneficial to physical health and social well-being. However, with extreme volumes, exercise may lead to addiction symptoms comparable with substance use and gambling disorders. Social dysfunction is a crucial element that constitutes exercise addiction (EA),...