Ningbo University

The Maximum Product of Sizes of Cross-\({t}\)-Intersecting Families

Abstract. Two families of sets [Formula: see text] and [Formula: see text] are called cross-[Formula: see text] -intersecting if [Formula: see text] for all [Formula: see text] and [Formula: see text]. Determining the maximum possible product of the sizes for such cross-[Formula:...

Oncolytic virus encoding decorin and the CD40 ligand boosts T-cell response and achieves a durable antitumor response during breast cancer treatment

Triple-negative breast cancer (TNBC) remains an aggressive disease with limited treatment options. Oncolytic adenoviruses represent a promising platform, but their efficacy as single agents is often insufficient. This study examined whether an oncolytic adenovirus co-delivering d...

An efficient multiscale numerical modelling method for thermal analysis of integrated circuits

As integrated circuits become more densely integrated with multiscale geometries and numerous microstructural features, thermally induced failure becomes a major concern, while direct finite element (FE) thermal analysis remains computationally expensive because it requires a ver...

Machine learning clustering of multidimensional clinical features identifies four prognostically distinct sepsis subtypes

Sepsis is highly heterogeneous, and traditional “one-size-fits-all” treatment approaches are insufficient for optimal risk stratification. Using the MIMIC-III database, we employed unsupervised machine learning (k-means clustering) based on eight key clinical features (age, SOFA...

Effects of heat spreading resistance on configuration optimization and cooling performance of two-stage thermoelectric coolers

Two-stage thermoelectric coolers (TECs) are promising for applications requiring large temperature lifts. However, the heat spreading resistance (HSR) arising from dimensional mismatch is often neglected in conventional theoretical models, limiting the accuracy of performance ana...

Li+-Induced Enhancement of Excitonic Luminescence in γ-CuBr Single Crystals Grown by the Vertical Bridgman Method

Abstract The intrinsic defects in pure γ-CuBr crystal lead to obvious nonradiative recombination, thereby significantly suppressing its ultrafast free-exciton emission. In this study, we successfully grew undoped and Li+-doped CuBr:x%Li (x = 0, 1, 3, 5) single crystals using the...

Control of Electronic Properties of Organic–Inorganic MXenes via Surface Functionalization

Abstract Surface terminations critically affect the electronic structure of two-dimensional (2D) transition metal carbides and nitrides (MXenes), yet the synthetic exploration has been hindered by the lack of predictive factors. Here, we establish that the number of lone-pair ele...

Salt-marsh aboveground biomass estimation by integrating UAV LiDAR-derived canopy height and Sentinel-1/2 satellite data

Salt-marsh vegetation plays an important role in coastal wetland stability and blue carbon storage, and accurate aboveground biomass (AGB) estimation is essential for assessing wetland carbon dynamics. However, regional-scale AGB estimation based on optical remote sensing is ofte...

Integrated Multi-Omics Analysis Reveals ACO2 as an Oxidative-Stress-Related Biomarker in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory impairment. Oxidative stress plays an important role in disease progression in AD. However, the molecular mechanisms underlying oxidative stress in AD remain unclear...

Long-term stress induced by low bicarbonate alkalinity causes intestinal oxidative stress, gut microbiota imbalance and metabolic disorder in Scylla paramamosain

To investigate the effects of low bicarbonate alkalinity on intestinal health of Scylla paramamosain , we systematically evaluated the growth survival, intestinal antioxidant enzyme activities, and expression profiles of genes involved in immunity, inflammation, apoptosis and osm...

A Geometry–Energy–Trend Fusion Framework for Frame-Wise Human Dynamic Stability Assessment

Dynamic stability during human movement reflects interactions among body configuration, support conditions, mechanical state, and short-term state evolution. This study proposes a frame-wise stability score, S(t), integrating three dimensionless instability components: a height-a...

Pressure‐Induced Topochemical Reconstruction for Quenchable Metastable ZnIn 2 S 4 With Enhanced Photoelectric Effect for Artificial Synapses Application

ABSTRACT Layered ternary sulfide ZnIn 2 S 4 is an attractive visible‐light semiconductor for photodetection, photocatalysis, and neuromorphic optoelectronics, but its photoelectric output is limited by inefficient carrier separation and sluggish carrier dynamics. Pressure offers...

Effectiveness and Safety of Fixed‐Dose Combination Metformin and Empagliflozin in Type 2 Diabetes: A Prospective, Multicenter, Real‐World Study From China

BACKGROUND: This study assessed the real-world effectiveness and safety of a fixed-dose combination (FDC) of metformin and empagliflozin in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS: This prospective, multicenter, real-world study enrolled consecutive patient...

Velocity adaptive preview path tracking control for autonomous vehicles using deep reinforcement learning with Lyapunov function-based reward shaping

Traditional rule-based path tracking controllers of autonomous vehicles (AVs) often struggle with nonlinear vehicle dynamics, parameter tuning, and changes in road conditions. Learning-based methods partly address these issues, but remain limited in adapting to velocity changes,...

Potential mechanisms of endophytic Bacillus velezensis JR4 as a biocontrol agent against Sclerotinia sclerotiorum causing postharvest rot in carrot

Abstract Carrot production regions worldwide incur enormous annual economic losses due to postharvest white mold caused by Sclerotinia sclerotiorum . Biological control is a promising approach for controlling postharvest pathogens. This study investigated the biocontrol efficacy...

Ultimate compressive strength inversion in initially imperfect plates under different boundary conditions: A conservative assessment method

This study presents a predictive framework for the ultimate compressive strength (UCS) of initially deflected plates subjected to longitudinal axial compression under simply supported (SS) and clamped (CL) boundary conditions. A comprehensive database comprising 2800 non-linear f...

Pressure‐Activated and Retained Blue Emission in Melamine Through Hydrogen‐Bond and Packing Regulation

ABSTRACT Pressure provides a direct way to regulate molecular packing and excited‐state relaxation in organic crystals, but retaining pressure‐induced emission after decompression remains challenging. Here, we report pressure‐activated and retained blue emission in melamine (MA),...

Semantic-guided multi-scale spatio-temporal imputation network for iron ore sintering process

The sintering process is a critical stage in iron and steel production, where downstream optimization relies on sensor-collected process data. However, missing data frequently occur in industrial environments, and accurate imputation is challenging due to complex spatio-temporal...

Pyropia haitanensis cultivation enhances water quality and reshapes microbial communities in coastal water and connected aquaculture ponds

Seaweed cultivation offers nature-based bioremediation for aquaculture effluents, yet its cascading effects on microbial ecosystems remain poorly understood. This study evaluated Pyropia haitanensis cultivation impacts across four phenological stages in nearshore marine (Cultivat...

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

ABSTRACT The temporal lobes are key hubs for memory and cognition. Although 40 Hz transcranial alternating current stimulation (tACS) has shown potential cognitive benefits, evidence for accelerated bilateral temporal stimulation remains limited. This study aims to evaluate its c...