Nantong University

Waldenstrom’s macroglobulinemia in siblings: a single institutional experience with 10 cases at 25 years and a review of the literature

Waldenstrom’s macroglobulinemia (WM) is characterized by familial aggregation. The study displayed the characteristics and outcomes of patients with WM in siblings. Ten cases (five pairs) were recognized as WM in siblings. The earliest pair (cases 3 and 4) was identified in 2002...

Systemic Coagulation-Inflammation Index Predicts Functional Outcomes After Aneurysmal Subarachnoid Hemorrhage: Mediation by Delayed Cerebral Ischemia

The systemic coagulation-inflammation (SCI) index reflects both coagulopathic and inflammatory dynamics. We investigated its association with delayed cerebral ischemia (DCI) and functional outcome in aneurysmal subarachnoid hemorrhage (aSAH), explored the mediation effect of DCI...

Genomic predisposition is associated with the direction of sex chromosome evolution

Sex chromosome evolution is among the most dynamic genomic innovations in vertebrates, yet why some lineages evolve XY while others evolve ZW remains unclear. Using chromosome-level genomes from 19 geckos, we found that gecko sex chromosomes originated independently from 16 ances...

Tissue engineering scaffolds for the spinal cord: recent advances and future prospects

Spinal cord tissue engineering scaffolds represent a highly promising option for the treatment and repair of spinal cord injury (SCI). They have a wide range of potential applications and, as essential biomaterial carriers, can restore the multifunctional microenvironment. Since...

Amphiphile‐Induced Dual‐Domain PDOL Electrolyte Enabling Decoupled Ion Transport and Interfacial Stability in Li‐S Batteries

ABSTRACT Solid‐state lithium–sulfur (Li–S) batteries are widely regarded as promising storage systems owing to their intrinsic safety and high theoretical energy density. Nevertheless, their practical applications remain limited by coupled ion transport, interfacial instability,...

Facet‐Selective Interfacial Regulation for Rapid‐Kinetics and Dendrite‐Free Zn (100) Deposition With Enhanced Cathode Stability

ABSTRACT The crystallographic orientation of Zn deposition essentially controls the electrochemical efficiency of aqueous Zn metal batteries. While (002)‐oriented growth suppresses dendrites, its sluggish kinetics limit rate capability; the (100) plane enables faster deposition b...

Large Language Model for Verilog Code Generation: Literature Review and the Road Ahead

Code generation represents a critical intersection of Software Engineering (SE) and Artificial Intelligence (AI). Within this broader landscape, Verilog, as a representative hardware description language (HDL), is fundamental to Electronic Design Automation (EDA), recent research...

Transcriptomic profiling of inner ear hair cell spontaneous regeneration reveals the key role of dlx5a

Sensory hair cells (HCs) are susceptible to damage, typically causing permanent hearing and balance deficits in mammals due to limited regeneration. Understanding spontaneous regeneration in non-mammalian models offers key insights for restoring sensory function. Here, we establi...

Design, simulation and experimental validation of a single-shot piston burner for adjustable diesel PM generation toward confined space deposition

Diesel combustion particulate matter (PM) poses severe environmental and health risks, but the laboratory-scale batch-type, quantitative, and stable generation of diesel PM remain challenging due to the lack of dedicated generators. Here a single-shot piston burner was proposed,...

Nonorthogonal Polarization‐Multiplexed and Detachable Diffractive Processors

Polarization multiplexing provides an elegant route for parallel all-optical processing, yet its intrinsic orthogonality fundamentally limits channel capacity and interlayer interaction in diffractive systems. We present a detachable diffractive processor that leverages nonorthog...

Effects of Pretreatment Temperature on Ni/CeO 2 Catalysts for Low‐Temperature CO 2 Hydrogenation

ABSTRACT Metal–support interaction (MSI) plays a key role in the intrinsic properties of catalysts and related catalytic performance, and it is crucial to explore the correlation between the performance and MSI. Herein, two series of Ni/CeO 2 catalysts were synthesized, and their...

Terrain‐Adaptive Quadrupedal Locomotion Using Model Predictive Control With Impedance Control and SINDy Model Enhancement

ABSTRACT Quadrupedal robots operating in unstructured environments require adaptive control systems that can handle diverse terrain conditions without prior surface characterization. This paper presents an integrated control architecture that combines Model Predictive Control (MP...

A quantitative and visual detection probe based on isothermal nucleic acid amplification coupled with CRISPR/Cas12a system (INACS) for miR155 detection

MicroRNAs (miRNAs) have emerged as ideal biomarkers for early clinical diagnosis. Achieving the accurate detection of miRNAs plays a critical role for assuring its implementation in their clinical applications. In this study, we developed a dual-signal amplified ultrasensitive fl...

Moderate aortic stenosis identified during intensive care admission for a non-cardiac primary diagnosis and 90-day mortality: a retrospective cohort study using the MIMIC-IV echocardiography database

Abstract Background Moderate aortic stenosis is associated with reduced survival in ambulatory cardiology populations, but its prognostic significance when identified during an intensive care admission for a non-cardiac primary diagnosis is unknown. We examined its association wi...

Associations of maternal mood on the outcome of childbirth: a latent profile analysis

It is important to recognize that childbirth and the transition to the maternal role constitute a profound identity reconstruction, involving both the physical experience of labor and the psychological adaptation to motherhood, during which many women experience unstable and inte...

Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III study

Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR- activating mutations. In this phase III, randomized, double-bli...

Extraction-reasoning gaps in open-source LLM grading of liver pathology reports

Large language models (LLMs) may reduce the manual effort required to convert narrative pathology reports into structured research data, but it remains unclear whether their performance reflects extraction of explicit diagnostic labels or genuine histopathological reasoning. We e...

Integrated Transcriptomic and Machine-Learning Analyses Identify Shared Na+ Overload-Related Gene Signatures in Inflammatory Bowel Disease and Ankylosing Spondylitis

Background: Ankylosing Spondylitis (AS) and inflammatory bowel disease (IBD) exhibit substantial pathophysiological overlap, including dysregulated innate immunity, barrier dysfunction, and Th17-mediated inflammation. However, whether Na+ overload-related genes (NRGs) exhibit sha...

Decoupling Ion–Dipole Interactions via Competitive Coordination for Durable Dendrite-Free Zinc Metal Batteries

Abstract The aqueous zinc metal batteries (AZMBs) are famous for high-safety and high-energy-density, but limited by severe challenges around the Helmholtz plane layer such as the strong ion–dipole interactions between Zn 2+ and H 2 O, resulting in slow desolvation processes and...

Development of machine learning models for predicting delirium in elderly patients after thoracic surgeries

Postoperative delirium (POD) is a frequent neurological complication following anesthesia and surgery, which is associated with increased comorbidities and mortality. The current study developed and internally validated a machine learning model for predicting POD in elderly patie...