Nantong University

Predicting insulin resistance in non-diabetics

This cross-sectional study aimed to compare obesity indicators for predicting insulin resistance using machine learning. Data were obtained from NHANES 2015 to 2018, focusing on a nondiabetic adult population. Insulin resistance was defined as HOMA-IR ≥ 75th percentile of the tra...

Dual-Functional Interface Molecular Engineering of Conductive MOF Nanoarrays for Oxygen Evolution Reaction

Abstract Drawing conceptual inspiration from the inorganic–organic hybrid architecture of natural Photosystem II, this work presents a dual-functional interface molecular engineering strategy. A Ni(TCNQ)2-FcDA nanoarrays (NAs) composite catalysts were constructed by anchoring fer...

Experimental and numerical investigation into the stripping mechanism of Grade-A marine steel during high-pressure water jet impingement

This study investigated the removal behavior and stripping mechanisms of corrosion products during high-pressure water jet rust removal, using a two-component epoxy coating as a rust-layer substitute. Numerical simulations and impingement experiments under different jet pressures...

LFT-YOLO: Lightweight Feature Transfer and Adaptive Upsampling for Small-Object Pine Wilt Disease Detection in UAV Imagery

Monitoring forest diseases is essential for sustainable forestry management and ecological security. However, unmanned aerial vehicle (UAV)-based forest inspection remains challenging because diseased pine canopies are often small, densely distributed, partially occluded, and eas...

Dynamic Covalent Prodrug Nanocomplex for Ultrasound‐Triggered Oxidative Stress Amplification and Synergistic Sonochemotherapy

ABSTRACT Essential micronutrient Vitamin B 2 (VB 2 ) is a bioactive compound with sonodynamic activity; however, it suffers from hydrophilic limitations. Herein, a dynamic prodrug nanocomplex (PTX‐PBA/VB 2 ) was constructed via phenylboronic acid‐diol interaction between VB 2 and...

Molecular subclassification of MGMT-unmethylated high-grade glioma identifies divergent tumor states and therapeutic vulnerabilities

MGMT-unmethylated high-grade glioma (HGG) is associated with poor response to temozolomide and limited therapeutic options. However, substantial molecular heterogeneity exists within this clinically defined subgroup and remains insufficiently characterized. Transcriptomic and cli...

A high-resolution stalagmite record of hydrological drought in northern China around 6.6 ka BP

The Holocene Climatic Optimum was punctuated by significant decadal-to centennial-scale climate variability, despite its overall warm and humid conditions. However, the spatiotemporal patterns and underlying dynamics of these fluctuations, particularly in the northern fringe of t...

Creep and particle breakage in coral sand and development of a modified burgers model

This study investigates the high-pressure one-dimensional creep and progressive particle breakage of coral sand from the South China Sea. A series of high-pressure oedometer tests were performed under varying vertical stresses (1 ∼ 4 MPa), loading durations (up to 10,000 min), an...

Triglyceride-Glucose Index and 10-Year Atherosclerotic Cardiovascular Disease Risk: Associations of Obesity-Related Indices in Two Nationally Representative Populations

BACKGROUND: The triglyceride-glucose (TyG) index has been associated with atherosclerotic cardiovascular disease (ASCVD) risk. However, the associations of TyG-related indices combined with obesity measures, including body mass index, waist circumference (WC), waist-to-height rat...

Study on Thermal Properties and Crystallization Behavior of Silica‐Modified Polyetheretherketone Composites

ABSTRACT This study employs KH560 to surface‐modify nano‐SiO 2 , which is then melt‐blended with PEEK to prepare composites with loadings of 0–7 phr. At 3 phr, the melting temperature rose to 348.5°C, the melting enthalpy reached a maximum of 80.33 J g −1 , and the corrected crys...

Improved YOLOv11 Framework with Channel Attention for High-Precision Identification of Luffa Leaf Diseases

Early accurate identification of luffa crop diseases is essential for timely treatment and high-quality agricultural production. Currently, luffa disease diagnosis relies solely on manual field inspection, which is labor-intensive and error-prone, and lacks assessment uniformity....

The total serum N-glycome landscape of hematological malignancies

A holistic and dynamic view of the glycomic landscape in hematological malignancies (HMs) remains poorly characterized, hindering clinical the application of glycomics in HMs. We launched a large-scale analysis of multicenter cohorts, combining retrospective (n=1,370) and prospec...

ENOPH1 orchestrates KRASG12D/G13D-driven glycolytic reprogramming and colorectal cancer progression through modulating the TGF-β/SMAD pathway

Oncogenic KRAS mutations (G12D/G13D) drive metabolic reprogramming in colorectal cancer (CRC), yet targetable downstream effectors remain poorly defined. Here, we identify enolase-phosphatase 1 (ENOPH1) as an essential transducer directly upregulated by the KRAS–MEK–ERK axis. ENO...

A neutrophil-mimetic nanoplatform integrating lipid mediators and immunoregulation for myocardial repair

Myocardial infarction (MI) triggers excessive oxidative stress and uncontrolled inflammation, which impede cardiac repair. Conventional anti-inflammatory or antioxidant therapies often fail to restore immune homeostasis or promote tissue regeneration effectively. Hence, developin...

Load-Pressure-Based Source-Load-Matching Dynamic Pricing and Coordinated Optimization for Multi-Park Integrated Energy Systems

Given that fixed energy tariffs and demand-response compensation rates cannot adequately capture temporal variations in source-load conditions across multi-park integrated energy systems, this study develops a coordinated optimization approach driven by load-pressure-based dynami...

Cross-cultural validation and psychometrics’ assessment of Pathak-Wieten Stoicism Ideology Scale among Chinese older people with knee osteoarthritis

Stoicism ideology can generate expectations about ideal health - related behaviors. It affects individual health by persevering in the face of illness challenges. Measuring the stoic ideology of older adults with knee osteoarthritis (OA) would assist in tailoring culturally sensi...

PRP‐Integrated Conductive Hydrogels With Dynamic Crosslinking for Accelerated Wound Healing and Physiological Monitoring

ABSTRACT The capability to simultaneously promote wound healing and enable real‐time monitoring is critical for effective wound management, especially in dynamic and infection‐prone regions such as joints, yet unmet needs remain in clinical practice. Herein, we present a multifun...

Development and application of simple self-locking surgical tubing tourniquet for laparoscopic Pringle maneuver

Pringle maneuver is a critical technique for controlling hepatic inflow and minimizing blood loss during laparoscopic liver resection. However, traditional methods of performing this maneuver can be cumbersome in laparoscopic settings. This study introduces a simple self-locking...

DC-CD8+ T cell-associated inflammation and sustained indel-derived candidate peptide exposure in radiation enteritis

Purpose Radiation enteritis (RE) is a frequent and challenging complication of radiotherapy for abdominal and pelvic malignancies, characterized by intestinal epithelial damage, immune dysregulation, and inflammation. Current treatments are limited by poor efficacy and significan...

Effectiveness and Safety of Fixed‐Dose Combination Metformin and Empagliflozin in Type 2 Diabetes: A Prospective, Multicenter, Real‐World Study From China

BACKGROUND: This study assessed the real-world effectiveness and safety of a fixed-dose combination (FDC) of metformin and empagliflozin in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS: This prospective, multicenter, real-world study enrolled consecutive patient...