Ministry of Health

Is Eligibility Enough? Pretreatment Prediction of Failure to Reach a Second Cycle of [177Lu]Lu-PSMA Radioligand Therapy

Background/Objectives: Current guidelines define no absolute contraindication to prostate-specific membrane antigen (PSMA)-targeted radioligand therapy (RLT), yet some patients receive only a single cycle. We aimed to characterize this single-cycle attrition (SCA) and derive an e...

Health literacy as a predictor of family planning attitudes in young men in Ankara, Türkiye

Family planning is a key component of reproductive health; however, young men's attitudes and knowledge remain understudied. This study aimed to examine the relationship between sexual health literacy and family planning attitudes among young men. This cross-sectional, descriptiv...

Association of Platelet–Albumin–Bilirubin and Albumin–Bilirubin Scores with Angiographic No-Reflow in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary PCI

Background: The platelet–albumin–bilirubin (PALBI) and albumin–bilirubin (ALBI) scores integrate routinely available laboratory parameters with potential relevance to microvascular injury. We investigated their associations with angiographic no-reflow and incremental predictive v...

Association between the C-reactive protein-to-albumin ratio and mechanical circulatory support device application in patients with advanced heart failure

Abstract Background The C-reactive protein-to-albumin ratio (CAR) is an easily accessible biomarker that reflects both systemic inflammation and nutritional reserve. This study aimed to evaluate the association between CAR and mechanical circulatory support (MCS) device applicati...

Calming the Adrenergic Storm: Mechanical Support Devices as a Life-Saving Stormbreaker in Iatrogenic Takotsubo Syndrome

Takotsubo syndrome is a cardiomyopathy characterized by transient ventricular dysfunction caused by excessive sympathetic discharge, which may potentially lead to a fatal outcome. This case report presents the successful management of a 41-year-old female patient with iatrogenic...

Sequential changes in serum adipokines and their clinical associations in critically ill COVID-19 patients

Adipokines regulate metabolic and inflammatory pathways and may be altered during critical illness. We explored sequential serum adipokine concentrations and their associations with nutritional and clinical variables in critically ill COVID-19 patients. This prospective observati...

Prognostic Value of Systemic Inflammation Markers and Clinical Factors in Grade 4 Diffuse Glioma: A Multicenter Retrospective Real-World Study

Background/Objectives: Systemic inflammation contributes to tumor growth and spread. We aimed to evaluate the association of pretreatment inflammatory indices and clinical and laboratory factors with survival in newly diagnosed grade 4 diffuse glioma. Methods: A total of 120 pati...

Multiparametric MRI differentiation of ovarian endometriomas and hemorrhagic cysts: Quantitative shading, ADC measurements, and morphological sign analysis

Background Differentiating ovarian endometriomas from hemorrhagic cysts matters because their management differs. Purpose To evaluate whether a multiparametric magnetic resonance imaging (MRI) approach improves differentiation of endometriomas from hemorrhagic cysts over conventi...

A simple clinical–laboratory risk score for preoperative identification of ovarian torsion: a retrospective diagnostic study

Timely diagnosis of ovarian torsion remains challenging due to nonspecific clinical presentation and limitations of imaging. Delayed recognition may result in ovarian loss. Simple, readily available tools to support early risk stratification are therefore needed. In this retrospe...

The Comparative Prognostic Value of the Interim PET Deauville Score and ΔSUVmax in Classical Hodgkin Lymphoma: A Real-World Study of Imaging and Inflammatory Markers

Background: Interim [18F]FDG-PET/CT with the Deauville score (DS) is central to response assessment in classical Hodgkin lymphoma (cHL). Quantitative ΔSUVmax and the lymphocyte-to-monocyte ratio (LMR) may refine the DS, but ΔSUVmax thresholds vary across cohorts and have rarely b...

Impact of the COVID-19 pandemic on the distribution and antimicrobial resistance patterns of urinary pathogens: a retrospective analysis from a single tertiary care center

Monitoring antimicrobial resistance in urinary tract infections (UTIs) is essential for guiding empirical treatment. This study aimed to evaluate changes in the distribution of Enterobacterales and their antimicrobial resistance patterns the pre and post COVID-19 period. Urine cu...

Biomechanical consequences of coronoidectomy on mandibular condylar stress distribution under simulated traumatic loading: a comparative finite element analysis

The coronoid process is a major temporalis insertion site and may contribute to load distribution within the mandibular ramus–condyle complex. Coronoidectomy is well established for restoring mouth opening in trismus and ankylosis, but its biomechanical consequences for condylar...

Comparative Efficacy of Modified Single-Patch versus Double-Patch Techniques in Atrioventricular Septal Defect Repair

Aim: This study aims to compare the early- and mid-term outcomes of modified single-patch and double-patch techniques for complete atrioventricular septal defect (AVSD) repair. We hypothesized that the modified single-patch technique offers similar or superior efficacy while redu...

QT interval prolongation in the coronary intensive care unit: prevalence, associated drugs and clinical-genetic risk factors

We aimed to investigate the prevalence of QTc interval prolongation (QTcIP), QTc-prolonging drug exposure, and associated clinical and genetic risk factors in adult patients hospitalized in the Coronary Intensive Care Unit. This observational cohort study included 207 patients ho...

Biomarkers of Treatment-Escalation Risk by Obesity Status in Pediatric Asthma: A Development and External Validation Cohort Study

Background/Objectives: Obesity may alter the prognostic value of biomarkers in childhood asthma. We examined whether transforming growth factor beta 1 (TGF-β1), soluble suppression of tumorigenicity 2 (sST2), C-X-C motif chemokine ligand 8 (CXCL8), and insulin-like growth factor...

Arthroscopic Free Bone Block Transfer Technique Using Iliac Crest Autograft With Anchor‐Button Fixation for Glenohumeral Instability and Glenoid Bone Loss

Abstract Bone block transfer for the treatment of glenohumeral instability with severe glenoid bone loss or multiple recurrences has grown in popularity in recent years. In this technical note, we described an arthroscopic‐assisted free bone block transfer technique, using a spec...

Posterior mediastinal unicentric Castleman disease treated by video-assisted thoracoscopic surgery

Castleman disease (CD) represents an uncommon lymphoproliferative condition that can manifest as a mediastinal mass and resemble other thoracic pathologies. Establishing a definitive diagnosis before surgery is often difficult, making histopathological analysis crucial. We presen...

Beyond Systemic Inflammation: The Complementary Role of Cellular Stress Markers in Predicting STEMI Outcome. Comment on Magureanu et al. Early Inflammatory Biomarkers, Ventricular Dysfunction and In-Hospital Mortality in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Diagnostics 2026, 16, 1978

I read with interest the recently published article by Magureanu et al [...]

Validity and reliability of the Turkish version of the ORTO-R in an adolescent clinical sample

Orthorexia nervosa refers to a pathological preoccupation with healthy eating characterized by rigid dietary rules, excessive concern about food purity, and distress when these rules are violated. Despite growing clinical interest, validated instruments for assessing orthorexic t...

Clinical significance of prenatally diagnosed clenched hand: genetic associations and pregnancy outcomes

To evaluate associated anomalies, genetic findings, and pregnancy outcomes of fetuses with clenched hand detected on prenatal ultrasonography. This retrospective cohort study included 40 pregnancies with a prenatal diagnosis of clenched hand managed at Ankara Bilkent City Hospita...