Institution
Ministry of Health
Recent research
- Health & MedicineOpen access
Abstract Background Complete blood count-derived inflammatory indices have been associated with miscarriage, but the incremental value of the aggregate index of systemic inflammation (AISI) beyond established indices such as the systemic immune-inflammation index (SII) remains un...
- Health & MedicineOpen access
Background/Objectives: Rosacea is a chronic inflammatory skin disease that requires long-term management and continuous patient education regarding triggers, skincare practices, and treatment adherence. In recent years, patients have increasingly turned to online platforms and ar...
- Health & Medicine
Model 1b analytical performance specifications – report on the Prague 2025 workshop
diagnostic medical devices (IVD MD) meet regulatory and quality standards before market release; for external quality assurance assessments; for quality control, monitoring reagent lot-to-lot variability, and allowing preanalytical variation assessments in labs; and for guiding p...
- Health & MedicineOpen access
Background Antifungal resistance (AFR) is a growing global health threat, particularly in low- and middle-income countries such as Zambia, where antifungals are often accessed without prescription. Antifungal stewardship (AFS) programs aim to optimise antifungal use, yet limited...
- Health & MedicineOpen access
Background Crimean-Congo haemorrhagic fever (CCHF) is a widely distributed viral haemorrhagic fever with expanding geographic range. As new regions encounter the disease, clinicians must make high-stakes decisions despite limited standardised management frameworks. Methods In thi...
- Health & MedicineOpen access
Background and Objectives: A considerable proportion of patients with asthma remain inadequately controlled despite treatment with inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) therapy. Single-inhaler triple therapy comprising an inhaled corticosteroid, a long-acting β...
- Health & MedicineOpen access
Objective: While advancements in radiotherapy and systemic agents have significantly improved survival rates in head and neck squamous cell carcinoma (HNSCC), managing long-term, treatment-induced toxicities remains a critical clinical challenge. This study aimed to develop a per...
- Health & MedicineOpen access
Mesenteric Hyaline Vascular Castleman Disease Presenting as Acute Mechanical Intestinal Obstruction
The Annali Italiani di Chirurgia (ISSN/eISSN: 0003-469X/2239-253X) is the oldest surgical journal in Italy. It covers all aspects of surgery and its allied disciplines, including elective, emergency and experimental surgery, as well as problems involving technology, teaching, org...
- Health & MedicineOpen access
Background/Objectives: Paragangliomas (PGLs) are rare neuroendocrine tumors, and data describing them from a medical oncology perspective are limited. We characterized clinicopathological features, tumor localization, and treatment outcomes. Methods: We retrospectively analyzed 4...
- Society & EconomicsOpen access
Mentalization and Emotion Regulation Difficulties in Adolescent Girls With Social Anxiety Disorder
INTRODUCTION: Social anxiety disorder (SAD) is a prevalent disorder that often begins during adolescence, leading to considerable challenges in social functioning and overall mental health. Previous studies have demonstrated that mentalization deficits and emotion regulation diff...
- Health & MedicineOpen access
Surgical treatment of anal fistula: classic elastic seton application and LIFT method
Anal fistulas remain a challenging problem in colorectal surgery, and the optimal sphincter-preserving technique is still debated. We compared the LIFT procedure and elastic seton application in terms of treatment outcomes, postoperative pain, anal continence, and quality of life...
- Biology
Asparagine synthetase deficiency: clinical features and experience with asparagine supplementation
Abstract Objectives Asparagine synthetase deficiency is a rare autosomal recessive neurometabolic disorder characterized by congenital and progressive microcephaly, severe developmental delay, epilepsy, and progressive cerebral atrophy. Therapeutic experience with L-asparagine su...
- Health & MedicineOpen access
Background: Benidipine is a long-acting calcium channel blocker used for the treatment of hypertension and chronic coronary syndrome. Although it effectively lowers blood pressure (BP), the relationship between BP reduction and improvement in angina-related health status during b...
- BiologyOpen access
Pathological complete response (pCR) is an established surrogate endpoint in aggressive breast cancer subtypes; however, its prognostic role in hormone receptor (HR)-positive/HER2-negative disease remains controversial. We aimed to evaluate clinicopathological predictors of pCR a...
- Health & MedicineOpen access
Knee osteoarthritis (OA) is a complex disease characterized by inflammation, cartilage degeneration, and tissue remodeling. Although many biomarkers have been investigated, the combined biological significance of systemic and local biomarkers is not fully understood. This study a...