Ministry of Education of the People's Republic of China

Cerebellar cortical amyloid deposition biases 18F-Florbetapir PET quantification with whole cerebellum as reference region

To investigate whether cerebellar cortical amyloid-beta (Aβ) deposition biases 18F-Florbetapir Aβ PET quantification when the whole cerebellum (WC) is used as the reference region, and to identify a stable reference region for quantification. Additionally, to establish an optimal...

Cellulose supramolecular ionogel with robust mechanical strength and thermal stability for flexible electronics

Abstract Ionogels hold great promise in the fields of flexible electronics and energy devices. However, a persistent challenge lies in the inherent trade‐offs among mechanical strength, ionic conductivity, and thermal stability. Here, we report a double‐network cellulose‐polyviny...

Use of a single CO₂ coolant in a Cascade manner for thermal protection of hypersonic vehicles

To address the thermal protection of hot-end components in hypersonic vehicles under extreme high-enthalpy aerodynamic heating, this study proposes and experimentally validates a channel–film combined cooling scheme based on the cascaded use of a single CO₂ coolant. Tests were co...

Terahertz Spectroscopic Characterization of a Daidzein-Piperazine Crystalline Solid Form Prepared by Liquid-Assisted Grinding

Daidzein is a natural flavonoid with low aqueous solubility and bioavailability. The low-frequency terahertz spectroscopic characteristics and corresponding vibrational origins of the 1:1 daidzein–piperazine (DAI–PIP) crystalline system remain insufficiently explored. In this stu...

Flexible Room‐Temperature Phosphorescent Materials With Matrix‐Independent Luminescence Enabled by Host–Guest Encapsulation

ABSTRACT Flexible room‐temperature phosphorescence (RTP) materials hold great promise for a wide range of optical applications. However, the strong interdependence between luminescent and mechanical properties severely hampers further advances in this field. Herein, we report a γ...

Mechanism of coalburst triggered by thrust fault slipping based on field monitoring, indoor experiments and numerical simulation

Abstract Coalburst disasters induced by thrust fault slip frequently take place in underground coal mines and often lead to severe roadway damage and personnel casualties. However, the triggering mechanism of coalburst remains unclear. Combined with field monitoring, physical ana...

An AI-driven reconstruction of global surface temperature with emphasis on refining the Antarctic record

Abstract. Accurate estimates of long-term surface temperature (ST) changes are fundamental not only for assessing observed warming, but also for improving the reliability of future climate projections. However, substantial missing information in global ST datasets, remains a majo...

Identification of annexin A10 as a candidate serum biomarker associated with neurological outcome after cardiac arrest

Accurate early neurological prognostication following cardiac arrest remains a major clinical challenge because of post-resuscitation brain injury. Although biomarkers such as neuron-specific enolase (NSE) and neurofilament light chain (NfL) are widely investigated, limitations i...

Isolation, Molecular Characterization, and Pathogenicity Evaluation of a Genotype GI Feline Calicivirus Isolate

Feline calicivirus (FCV) is a highly heterogeneous pathogen and a major cause of feline upper respiratory tract disease, highlighting the need for continuous surveillance of its genetic diversity and pathogenic characteristics. In this study, we isolated and comprehensively chara...

Glucose-TOR-PDCB signaling restricts cell-to-cell communication through callose deposition

Plant cells are connected by plasmodesmata (PD), membrane-lined channels that facilitate cell-to-cell transport. Forward genetic screens to uncover regulators of PD transport identified mutants with increased ( ise1 to ise4 ) or decreased ( dse1 ) PD trafficking during embryogene...

Indole-3-propionic acid is an endogenic agonist of hypoxia-inducible factor-1α to protect the heart against hypoxia

Abstract Tryptophan catabolism by the gut microbiota is increasingly recognized as a hub connecting environmental challenges to cardiovascular health. By systematically profiling tryptophan metabolites in humans who had moved from low altitude to an altitude of 4300 m and in mice...

Muscle‐Inspired Learnable Liquid Crystal Elastomer Enabled by Dynamic Reaction and Mesogenic Re‐Orientation

ABSTRACT The learning capability of skeletal muscle enables adaptive enhancement in response to different stimuli, making it a promising concept in soft matter. The key point is how to construct multiscale muscle‐like structures and acquire “learning” capability, but these two fu...

Temporoparietal structural-functional coupling abnormalities in drug-naïve youths with major depressive disorder and suicidal ideation

Major depressive disorder (MDD) in youth is associated with higher suicide risk. Although white matter and functional connectivity abnormalities have been reported in MDD patients with suicidal ideation (SI), how brain structure and function interact abnormally remains unclear. W...

DS-RangeNet: Lightweight Dual-Stream LiDAR Semantic Segmentation for Industrial Indoor Environments

Real-time LiDAR semantic segmentation for industrial AGVs must distinguish repeated structures and weak glass returns while remaining robust to sensor-dependent intensity and tight edge computing budgets. We introduce DS-RangeNet, a lightweight range image network that processes...

Longitudinal brain dynamics and prediction of craving changes in individuals with methamphetamine use disorder

Abstract Individuals with methamphetamine use disorder (MUD) exhibited functional and structural brain recovery during abstinence. However, longitudinal neural changes of large-scale brain networks after prolonged abstinence remain unclear. Here, energy landscape analysis was app...

Organic manganese as a functional micronutrient: Promoting metabolic health and sustainable growth in Litopenaeus vannamei.

< 0.05). In summary, although growth remained unaffected, organic Mn sources, particularly Mn-Gly and Mn-MHA, demonstrated superior bioavailability by enhancing antioxidant status, immune function, and hepatopancreas health as well as by regulating lipid metabolism.

Impact of pig farming activities on the gut microbiome and resistome of farmers: insights from metagenomics and Escherichia coli genomics

Intensive swine production entails high antimicrobial use and close human–animal microbial exchange, with potential to remodel the human gut ecosystem and promote cross-host antimicrobial resistance (AMR) transmission. To quantify the impact of occupational exposure on the human...

Identification of Senescence‐Associated β‐Galactosidase With Single‐Molecule Resolution

ABSTRACT The majority of human senescent cells exhibit overexpression of senescence‐associated β‐galactosidase (SA‐β‐gal), rendering this enzyme the most extensively utilized biomarker of senescence and a key prodrug target for intervening in aging. However, strategies for the au...

Mechanical behavior and fracture mechanisms of rock-backfill composites under different hole geometries and backfill conditions

Abstract Rock-backfill composites, as key load-bearing structures in deep mining, exhibit mechanical behavior and failure mechanisms that are predominantly controlled by excavation-induced hole geometry and backfill conditions. In this work, a series of uniaxial compression tests...

Research progress on biosynthesis and regulation of monoterpenoid compounds

Abstract Monoterpenoids are an important class of plant volatile natural products with broad applications in the food, fragrance, pharmaceutical, and agricultural industries. However, their conventional production largely relies on plant extraction, which is often constrained by...