Institution
Memorial Sloan Kettering Cancer Center
Recent research
- Health & Medicine
BACKGROUND: The incidence of rectal adenocarcinoma is rising in patients < 50 years old compared to those > 50. Nonoperative management and active surveillance have become a standard of care in rectal cancer treatment for those who achieve a complete response to neoadjuvant thera...
- Health & Medicine
Importance Hodgkin lymphoma (HL) is a lymphoid malignancy derived from B cells. Globally, there were 82 409 new cases of HL in 2022, associated with 22 701 deaths. In the US, 8720 incident cases of HL and 1150 deaths due to HL were reported in 2025. Classic HL (cHL) accounts for...
- Health & MedicineOpen access
The cGAS/STING pathway in cancer: translating innate DNA sensing into therapeutic potential
The cGAS/STING pathway is a central innate immune DNA-sensing system that links aberrant DNA species to innate immune and stress-response transcriptional programs and has emerged as a key regulator of tumor-immune interactions. In cancer, pathway outputs are shaped by interconnec...