Medical University of Silesia

Diagnostic Value of Gastrointestinal Ultrasound (GIUS), Including Doppler and Contrast-Enhanced Ultrasound (CEUS), in the Assessment of Inflammatory Bowel Disease Activity: A Scoping Review

Background/Objectives: Treat-to-target management of inflammatory bowel disease (IBD) requires frequent, accurate assessment of disease activity. Endoscopy remains the reference standard, but its invasiveness limits repeated use, which has increased interest in gastrointestinal u...

The Prognostic Role of HPV Status Based on the Analysis of Outcomes of Combined Treatment of Oral Cavity and Oropharyngeal Cancers

Background and Objectives: The aim of the paper is to assess the impact of HPV DNA on the survival and cure rates of patients with newly diagnosed head and neck cancers. Materials and Methods: The study group consisted of 51 patients with squamous cell carcinoma of the oral cavit...

Early and Long-Term Results of 101 Consecutive Patients After Transcarotid Transcatheter Aortic Valve Implantation

Background/Objectives: Transcatheter aortic valve implantation through the common carotid artery (TC-TAVI) is one of the possible treatment options for patients with ineligible transfemoral approach. The aim of our study was to evaluate the efficacy and safety of patients treated...

Awareness, Access and Use of Shear Wave Elastography and Myotonpro Among Physiotherapy Students and Practicing Physiotherapists: A Cross-Sectional Survey

Background: Shear wave elastography (SWE) and MyotonPro provide quantitative information on tissue mechanical properties and may complement conventional musculoskeletal assessment. This study assessed awareness, access, use, and perceived clinical utility of these technologies am...

Anti-inflammatory diet as an element supporting the treatment of selected gynecological diseases — literature review

Low-grade chronic inflammation plays an important role in the pathogenesis of many gynecological diseases, including polycystic ovary syndrome (PCOS), uterine fibroids, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD) and endometriosis. The aim of this paper wa...

CYBA Gene Polymorphisms, Lipid Parameters and Atherogenic Indices: A Cohort Study of Healthy Individuals Without Prior Lipid-Lowering Therapy

Single-nucleotide polymorphisms (SNPs) in the CYBA gene, encoding the p22phox subunit of vascular NADPH oxidases, have been associated with atherosclerosis-related disorders. This association may partly reflect their involvement in lipid metabolism. We investigated the effects of...

Assisted Reproductive Technology and Risk of Congenital Heart Defects in the Offspring: A Systematic Review and Meta‐Analysis

Background To date, >10 million children have been conceived via assisted reproductive technology (ART) globally. However, there are some concerns about potential adverse outcomes associated with ART‐conceived pregnancies, including the risk of congenital heart defects (CHDs). Th...

Cardiac Myosin‐Binding Protein C for Diagnosis of Myocardial Infarction in Patients With Prior Coronary Artery Bypass Grafting

Background Diagnosing myocardial infarction in patients with prior coronary artery bypass grafting (CABG) remains challenging, primarily because of lower diagnostic accuracy of high‐sensitivity cardiac troponin (hs‐cTn). cMyC (cardiac myosin‐binding protein C), because of its fas...

The Impact of Vitamin E Intake on Cardiometabolic Outcomes of Testosterone Replacement Therapy in Men with Late-Onset Hypogonadism

Androgen deficiency is associated with an increased risk of cardiometabolic complications, whereas vitamin E may exert protective effects against cardiovascular and metabolic diseases. This pilot prospective cohort study examined whether cardiometabolic outcomes observed during e...

Serial Static Infrared Thermography for Intraoperative and Postoperative Surface-Temperature Monitoring of Free-Flap Skin Islands in Paediatric Craniofacial Reconstruction: A Technical Feasibility Study

Background/Objectives: This single-patient retrospective study evaluated the technical feasibility of serial infrared thermography (IRT) for intraoperative and postoperative surface-temperature documentation of free-flap skin islands and its descriptive concordance with clinical...

Analysis of Mercury Content in Medicinal Plants Popular in Poland

The use of herbal medicinal products and dietary supplements has increased significantly in recent years. Insufficient knowledge regarding the effects of herbal raw materials, as well as their potential adverse effects and interactions with medications and food, poses a considera...

Rare bacterial infections and metagenomics: current diagnostic and therapeutic challenges—a literature review

This review aims to summarize the diagnostic and therapeutic challenges associated with rare bacterial infections, with particular focus on Whipple’s disease, melioidosis, Lemierre’s syndrome, and nocardiosis. It also evaluates the clinical utility of emerging molecular diagnosti...

Emergency abdominal surgery: variation in closure practice and early postoperative outcomes in the prospective multicentre PROPHECY study

Emergency abdominal surgery carries a high risk of postoperative morbidity, yet prospective multicentre data on real-world abdominal wall closure practices remain limited. This interim analysis of the PROPHECY study aimed primarily to characterise current abdominal wall managemen...

Endometriosis at the Molecular Crossroads: Pathways, Targets, and Emerging Therapeutic Strategies

Endometriosis affects an estimated one in ten women of reproductive age and remains defined clinically by the presence of endometrial-like tissue outside the uterine cavity, yet its persistence depends on biological processes that extend well beyond estrogen exposure. This review...

Real-World Clinical Management of Keratoconus in Europe and the Middle East: A Multicountry Survey on Diagnostic and Surgical Practices (Keratoconus in Mind - KIM Project)

Purpose: This study aimed to describe the current management of patients with keratoconus in European and Middle Eastern countries through the collection of real-world data from clinicians actively managing keratoconus. Methods: Computer-assisted web interviewing survey targeting...

SYSTEMIC ISOTRETINOIN AND ORAL HEALTH: SALIVARY, MUCOSAL, AND PERIODONTAL CHANGES AND IMPLICATIONS FOR DENTAL PRACTICE

Systemic isotretinoin is widely used for the treatment of severe acne and is frequently associated with mucocutaneous adverse effects. Oral manifestations may include xerostomia, reduced salivary flow, cheilitis, mucosal discomfort, and changes in periodontal parameters, but thei...

Beyond electrical stimulation: toward neurotransmitter-mediated synaptic prostheses

Abstract Synaptic dysfunction and neurotransmitter imbalances are central to the pathogenesis of numerous neurological disorders. Conventional systemic pharmacological treatments often lack spatiotemporal precision, while traditional electrical stimulation is fundamentally limite...

Association Between Self-Reported Weekly Physical Activity Duration and Echocardiographic Cardiac Structure and Function in Adults Aged ≥ 45 Years: A Cross-Sectional Study

Background: The association between habitual physical activity duration and cardiac structure and diastolic function remains incompletely characterized. Objective: To evaluate the relationship between self-reported weekly physical activity duration and echocardiographic parameter...

Comparative diagnostic performance of motor-evoked potential alarm thresholds for predicting postoperative neurological decline in intradural extramedullary spinal tumor surgery: a systematic review and meta-analysis

Variability in motor evoked potential (MEP) alarm thresholds limits interpretation of intraoperative monitoring during intradural extramedullary (IDEM) tumor surgery. We aimed to compare predefined MEP thresholds for predicting postoperative neurological decline. PubMed, Embase,...

Longitudinal Changes in QTc Interval in Cancer Patients After the Initiation of Systemic Therapy: Analysis of the ONCOECHO Study Cohort

Background/Objectives: Anticancer therapies are associated with a prolongation of QT interval of electrocardiogram (ECG), increasing the risk of arrhythmias. To evaluate this risk in cardiovascular disease-free subjects with cancer, ECG recorded at baseline, months 3, 6 and 12 fr...