Medical University of Silesia

Clot-dynamics phenotypes in septic patients assessed with rotational thromboelastometry: a retrospective cohort study

Sepsis is frequently accompanied by coagulopathy, but standard coagulation tests provide only a limited view of hemostatic function. In contrast, viscoelastic hemostatic assays offer real‑time assessment of clot initiation, propagation, firmness, and lysis, potentially revealing...

Recommendations of Multiple Sclerosis and Neuroimmunology Section of the Polish Neurological Society and the Polish Society of Gynecologists and Obstetricians for family planning and pregnancy management in women with multiple sclerosis: an update

INTRODUCTION: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the Central Nervous System that most commonly affects females of reproductive age. Therefore, the issue of family planning is relevant in this population, especially in the context of starting a...

The Functional Impingement Subacromial Ultrasound (FISUN) test: a conceptual and methodological framework for functional assessment of the subacromial space

Ultrasonography (renamed from the Journal of Korean Society of Ultrasound in Medicine in January 2014), the official English-language journal of the Korean Society of Ultrasound in Medicine (KSUM), is an international peer-reviewed academic journal dedicated to practice, research...

Differential expression of TGF-β1, TGF-β2, and TGF-β3 across WHO grades in meningioma: convergent evidence from mRNA, methylation, miRNA, and protein analysis

Meningiomas show biological heterogeneity not captured by WHO grading alone. TGF-β signaling has been implicated in meningioma pathobiology, yet a systematic, grade-stratified, isoform-resolved characterization of TGF-β1, TGF-β2, and TGF-β3 across transcriptional, epigenetic, pos...

Residual Inflammatory Potential in Patients with Treated Non-Definite and Definite Familial Hypercholesterolaemia: A Clinical Study

Background: Familial hypercholesterolemia (FH) is associated with accelerated atherosclerosis and an increased risk of cardiovascular disease. Aims: To evaluate circulating biomarkers of inflammation and atherosclerosis in patients with clinically suspected FH stratified accordin...

Prognostic Factors and Survival in Pericardial Mesothelioma: A Systematic Review and Quantitative Analysis

Background: Primary pericardial mesothelioma (PPM) is a rare and aggressive tumor. We aimed to analyze diagnostic pathways and factors influencing survival. Methods: A systematic review was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD4202612...

Efficacy and tolerability of venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukemia – real-world analysis of Polish adult leukemia study group

We collected clinical data on 363 patients with relapsed/refractory chronic lymphocytic leukemia (RR-CLL) treated with venetoclax-rituximab (VR) in a real-world setting. The median age was 69.5 years (range, 32.5–91.6 years), and the median number of prior lines of therapy was 2...

Challenging creation of a hemodialysis arteriovenous fistula (AVF) in a patient with high division of the radial artery

The radial artery (RA), a branch of the brachial artery, is frequently utilized in a variety of medical procedures: by cardiologists for cardiac catheterization, by nephrologists for arteriovenous fistula creation, by interventional radiologists, and by plastic surgeons for free...

Beyond Chemical Compliance: A Critical Review Toward Microbiome‐Informed Ecological Exit Criteria for Bioremediated Soils

ABSTRACT Chemical compliance remains the usual endpoint for closing contaminated‐soil remediation projects, although it does not establish recovery of soil function or the durability of the post‐treatment state. This critical review examines when microbiological evidence can cont...

Interplay Between Valvular Heart Disease and Psychiatric Disorders: Mechanisms, Manifestations, and Management

Valvular heart disease (VHD) and psychiatric disorders are each highly prevalent, yet their co-occurrence is underappreciated in clinical practice. Patients carrying both diagnoses present particular management challenges because the pathologic relationship between the two condit...

Selected clinical parameters of cardiology patients, their health-promoting behaviors and quality of life in relation to body mass index

Taking into account the significant role of weight disorders and various preventive measures in maintaining human health, as well as the ever-increasing importance of assessing quality of life during the therapeutic process, an interesting research area seems to be analyses compa...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

Microfragmented Adipose Tissue in Pain Management: Bridging Regenerative Biology and Clinical Therapeutics

Regenerative medicine has emerged as a transformative paradigm in contemporary healthcare, shifting the therapeutic focus from symptomatic management toward the restoration of tissue structure and function through biologically active interventions. Within this framework, adipose-...

Enhancing Diagnostic Precision in Fuchs Dystrophy: Comparative Evaluation of REVO HR and FC130 OCT Systems

Purpose: To compare the diagnostic performance of two anterior segment optical coherence tomography devices, REVO FC130 and REVO HR, in patients with Fuchs endothelial corneal dystrophy (FECD). Methods: This prospective cross-sectional study included 33 patients with FECD. Each p...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

Late diagnosis of OHVIRA syndrome — case series and literature review

OBJECTIVES: The aim of this study was to present three adult cases of obstructed hemivagina, and ipsilateral renal anomaly (OHVIRA) syndrome diagnosed in different gynecological centers in Poland. The clinical presentations, diagnostic imaging, surgical treatment, and outcomes we...