Medical University of Lodz

Familial Co‐Aggregation of Neurodevelopmental Conditions and Childhood‐Onset Type 1 Diabetes

ABSTRACT Aim Childhood‐onset Type 1 diabetes (T1D) is associated with neurodevelopmental conditions (NDCs). We examined whether this association extends to relatives and assessed phenotypic, genetic, and environmental correlations between T1D and NDCs. Methods Using Swedish regis...

Recommendations of Multiple Sclerosis and Neuroimmunology Section of the Polish Neurological Society and the Polish Society of Gynecologists and Obstetricians for family planning and pregnancy management in women with multiple sclerosis: an update

INTRODUCTION: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the Central Nervous System that most commonly affects females of reproductive age. Therefore, the issue of family planning is relevant in this population, especially in the context of starting a...

General Assessment of Indole Derivatives and Wnt Pathway as Potential Key Factors Against Various Diseases, with Particular Emphasis on Thyroid Tumors

Indoles are chemical compounds that naturally occur in Prokaryotes and Eukaryotes. For example, indole alkaloids mainly occur in plant families such as Nyssaceae, Rubiaceae, Apocynaceae, and Loganiaceae. The popularity of indoles has led to further research into their function an...

Efficacy and tolerability of venetoclax plus rituximab in relapsed or refractory chronic lymphocytic leukemia – real-world analysis of Polish adult leukemia study group

We collected clinical data on 363 patients with relapsed/refractory chronic lymphocytic leukemia (RR-CLL) treated with venetoclax-rituximab (VR) in a real-world setting. The median age was 69.5 years (range, 32.5–91.6 years), and the median number of prior lines of therapy was 2...

Are Signal Peptides Hidden Regulators of Neurodegenerative Disease?

Canonical signal peptides (SPs) are short N-terminal sequences that direct nascent proteins into the secretory pathway, but their role extends far beyond protein targeting. Advances in sequencing and computational tools have enabled their systematic identification across proteome...

Advances in Nuclear Medicine Diagnostics: The Promise of Radiolabeled Dendrimers

One of the most widespread causes of mortality is cancer, and its early diagnosis is a key element of modern medicine. A crucial role is played by imaging techniques such as positron emission tomography (PET), single-photon emission computed tomography (SPECT), and computed tomog...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications - Supplementary Methods

Supplementary Materials and Methods for "KSR2 is a novel oncogene in TAL1 subtype of T-cell acute lymphoblastic leukemia with potential clinical and prognostic implications" accepted for publication in Haematologica (2026) The published article includes an abbreviated Methods sec...

Vitamin D levels and other factors associated with depressive symptoms and cognitive impairment in the oldest-old patients with diabetes

The aim of the study was to determine the serum 25-hydroxvitamin D levels in patients aged over 85 years with type 2 diabetes and identify the factors (including vitamin D levels) associated with comorbid depressive symptoms and mild cognitive impairment (MCI). A group of 188 T2D...