Lomonosov Moscow State University

4-Oxo-7-Halosubstituted Phenanthroline Diamides Bifunctional Reactivity: A Synthetic Pathway to Unsymmetrical Polydentate Ligands

An efficient approach to unsymmetrical 1,10-phenanthroline-2,9-dicarboxamides based on the bifunctional reactivity of 4-oxo-7-haloderivatives is reported. These substrates exhibit orthogonal reactivity, enabling selective nucleophilic aromatic substitution at the C7 position alon...

Natural Compounds of Plant Origin–Promising Agents in the Fight Against Antibiotic Resistance

Antimicrobial resistance (AMR), or antibiotic resistance of microorganisms, is becoming a global threat to healthcare, and strains with multidrug resistance (MDR) pose significant challenges for drug development programs. New mechanisms of antimicrobial traits render existing dru...

Sums of Schlömilch series associated with Anger and Weber functions with coefficients containing trigonometric functions

Some new sums of series involving the Anger and Weber functions, the argument of which depends on the summation index, as well as trigonometric and power or rational functions, are derived in closed form using complex analysis.

Local Glucocorticoid Metabolism in Post-traumatic Stress Disorder: The Emerging Role of 11-hydroxysteroid Dehydrogenases

Post-traumatic stress disorder (PTSD) is a complex psychiatric condition arising from exposure to severe trauma, characterized by intrusive memories, avoidance, negative alterations in cognition and mood, and hyperarousal.Despite advances in understanding its neurobiology, effect...

Strategic Documents Shaping Russia’s Digital Project Development

Digitalization is an ongoing global process. The digitalization of the economy and public administration makes it necessary to identify specific prospects for digital development, and strategic planning documents can serve as a key driving factor. This article describes the strat...

Strategic Directions for Human Resources Development in Industrial Water Use

Human resource development is crucial for the rational management of water resources in industrial enterprises amid digital transformation, the environmental agenda, and the transition to sustainable development. Grounded in Professor Vladimir L. Kvint’s concept of strategizing,...

Минералого-геохимические особенности углей Мугунского месторождения и источники сноса в период их формирования

This study presents a comprehensive mineralogical and geochemical investigation of lignites from the Mugun deposit within the Irkutsk Coal Basin. The relevance of the research is determined by the need for the rational utilization of coal resources amid growing interest in the re...

Cortical Bipolarity Underlies Microtubule-Dependent Bidirectional Gliding in the Deep-Branching Apicomplexan Polyrhabdina pygospionis (Gregarinassina)

Manuscript in preparation — 30 August 2026 This is a work-in-progress manuscript prepared within Project No. 09I03-03-V04-00162, funded by the EU NextGenerationEU through the Recovery and Resilience Plan for Slovakia. This version is publicly deposited to document the current sta...

Arithmetic Universe: Riemann-Zeta Spectral Emergence, Prime-Phase Information, and Topological Holographic Cosmology

We have presented an integrated Arithmetic Universe framework linking the Riemann-zeta spectrum to an emergent topological and holo- graphic cosmology. The Lambert coordinate describes the smooth spectral skeleton, while the prime phases reconstruct local arithmetic fluctuations....

Theoretical model of microparticle-assisted super-resolution microscopy

We present the three-dimensional theoretical model of microparticle-assisted super-resolution imaging that enables simulation of virtual image formation. The model shows that partial spatial coherence of the illumination is a key prerequisite for achieving super-resolution. We de...

A Chirality Calculation Algorithm for Supersecondary Protein Structural Motifs

Coiled coils, collagen superhelices, and β-sheets belong to the supersecondary level of protein structure. Each of these classes of structural motifs is characterized by a particular chirality. However, methodology for mathematical determination of chirality of specific structure...

SIRT3 determines the sensitivity of cancer cells to mitochondrial targeting

Abstract SIRT3 is a mitochondria-localized member of the sirtuin family, playing a key role in cellular antioxidant defense. Its function in carcinogenesis and therapy response remains uncertain. In the present study, we sought to identify the role of SIRT3 in regulating cell dea...

Expanding the Genomic Spectrum of NHLRC2-Associated FINCA Disease: Integrated Bioinformatic Characterization of a Novel Deep Intronic Variant Predicted to Activate a Pseudoexon

NHLRC2-associated FINCA disease is an ultra-rare autosomal recessive multisystem disorder caused by biallelic pathogenic variants in NHLRC2. Its mutational spectrum and genotype–phenotype correlations remain incompletely defined, and the contribution of non-coding variants is poo...

Frequency control of superconducting resonators using integrated interferometers

Predictable frequency trimming of superconducting resonators at liquid-helium temperatures requires a tuning element whose usable range remains well defined despite screening currents and hysteresis. Here, we realize flux-controlled λ/4 coplanar-waveguide resonators terminated by...

HF Heating Effects as Seen From Below and Above: First Results of Joint SURA–Ionosfera‐M Experiment

Abstract This paper presents the first results of a coordinated experiment on the ionospheric plasma response to high‐frequency (HF) overdense heating, conducted using the SURA heating facility and the Ionosfera‐M satellite. The experiment combined ground‐based observations with...

Integrability of $$R^2$$ gravity cosmological models with radiation

Abstract We consider $$R^2$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msup> <mml:mi>R</mml:mi> <mml:mn>2</mml:mn> </mml:msup> </mml:math> gravity cosmological models with radiation. We find the general solution to the trace equation $$\Box R=0$$ <mml:math xm...

Novel Exact Solutions of the Duffing Equation: Stability Analysis and Application to Real Non-Linear Deformation Tests

In this study, novel exact solutions of the Duffing equation with their phase portraits are proposed and reasoned. It is shown that phase trajectories are initially elliptical and become distorted in the unstable area with the growth of the variable parameter in the damped case....

Ring Contractionof Bicyclic Lactams: A MolecularEditing Aza-Favorski-Type Approach to Tetrahydroquinoline-2-carboxylicAcids

Abstract Development of skeletal editing methods offers new horizons for the acceleration of drug discovery. An original aza-Favorski-type approach is described for the ring contraction of benzazepine-2-ones, providing versatile tetrahydroquinoline-2-carboxylic acids. The sequenc...

Use of a Macrokinetic Dose–Response Model for Assessing Permissible Levels of Cu(II) and Ni(II) in Soils of the Norilsk Industrial Region

Abstract— The results of a pot experiment aimed at establishing soil quality standards for the contents of Cu(II) and Ni(II) in different soil types of the southwestern part of Taimyr: podbur, cryoturbated peat gleyzem, raw-humus cryozem, and cryometamorphic gleyzem (Spodic Cryos...

Feasibility and preliminary outcomes of cognitive-motor training intervention for older working adults reporting subjective cognitive and physical complaints

Cognitive-motor interventions may help preserve and enhance cognitive, physical and sensorimotor function in aging populations, however, their feasibility for older adults working in cognitively demanding positions and experiencing subjective cognitive and physical complaints (SC...