Linköping University

Several multiple sequence alignment-perturbing methods enhance AlphaFold3 sampling of alternative protein states

Abstract Protein function often involves multiple conformational states. Several multiple sequence alignment-perturbing strategies, including stochastic subsampling, clustering, and column masking, have been shown to enhance AlphaFold2 (AF2) sampling of alternative protein states...

Studying Physical–Virtual Hybridisation in Everyday Life Through the Time‐Geographic Project Concept

Abstract This study proposes a time‐geographic approach for operationally defining and quantitatively measuring the physical–virtual hybridisation of daily activities. While hybridisation has been proposed to move beyond separating the usage of information and communications tech...

Combatting a Tobramycin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit: the impact of hygiene intervention and antibiotic substitution

Abstract Background Outbreaks of antibiotic-resistant bacteria in neonatal intensive care units (NICUs) is a significant risk to these vulnerable infants. This study describes a decade-long outbreak of tobramycin-resistant Staphylococcus aureus (TRSA) and the interventions implem...

Post-Fabrication Deprotection of Semiconducting Polymers for High-Performance Organic Electrochemical Transistors

Abstract Conventionally, the development of high-performance organic electrochemical transistor (OECT) devices heavily depends on side-chain optimization of glycolated and alkylated organic mixed ionic-electronic conducting polymers (OMIECs), which typically leads to a compromise...

Are patients receiving specialist palliative care thirsty? A qualitative interview study

Abstract Background Thirst is a potentially distressing yet under-researched symptom experienced by patients receiving specialist palliative care. Despite its clinical relevance, little is known about how patients experience thirst, or how it is assessed and managed in practice....

Core Strength and Side-Hop Interlimb Asymmetries Are Associated with Subsequent Traumatic Knee Injury in Female Football Players

The aim of this prospective cohort study was to examine the associations between muscle strength and functional interlimb asymmetries and the subsequent occurrence of traumatic knee injuries in female football players. A secondary aim was to evaluate the ability of asymmetry meas...

A review of selected Swedish contributions to instrumentation at neutron scattering facilities

Abstract The European Spallation Source in Lund, Sweden, is the next generation neutron research facility that will provide unprecedented capabilities for particle physics as well as materials and life science research through its high brightness, long-pulse neutron source and ad...

A Cyber-Resilient Zero Trust Architecture for Renewable Energy Communities

Abstract Renewable Energy Communities have emerged as a cornerstone of the rapid transition towards renewable energy sources, where individuals, businesses, and organizations collaborate to generate, share, and consume renewable energy. However, the effective realization of these...

Vacancy diffusion in transition metal diborides using diverse machine-learning potentials

Machine-learning interatomic potential (MLIP)-based molecular dynamics enables efficient exploration of mass-transport mechanisms in complex materials together with quantitative determination of diffusion coefficients at finite temperatures. Using an identical training dataset, w...

To Dope Mo 3+ in Colloidal Nanocrystals

ABSTRACT Mo 3+ shows intra‐configurational spin‐flip (ICSF) d → d electronic transitions, emitting near‐infrared‐II (NIR‐II) radiation. Till date, the emission has been reported from Mo 3+ ‐doped into bulk host materials, in the powder or single crystalline forms. Here we report...

Who shapes Resilience Engineering? Gendered epistemic asymmetries in a socio-technical knowledge community

Resilience engineering is concerned with modelling adaptive capacity and performance variability in complex systems. As such, it constitutes a body of research and a knowledge community whose epistemic configuration may shape theoretical development primarily in ergonomics and so...

Leveraging neural network models for drug repurposing: a case study on cardiac hypertrophy

Abstract Drug repurposing has emerged as an attractive strategy in contemporary pharmaceutical research, presenting an opportunity to expedite drug discovery, minimize developmental costs, and mitigate risks associated with developing new pharmaceuticals. In this study, we invest...

Epitaxial MgSnN 2 on 4H‐SiC (0001): An Earth‐Abundant Nitride for Green Optoelectronics and Photovoltaics

ABSTRACT Group II–IV‐Nitrides has emerged as a novel class of Earth‐abundant semiconductors. Owing to their tunable bandgaps these materials are attractive candidates for replacing expensive Ga‐based alloys in photovoltaics and green‐gap optoelectronics. In this work, epitaxial g...

Decoupling Triplet Population from Intersystem Crossing in TADF Materials

Abstract The characterization of thermally activated delayed fluorescence (TADF) relies on detecting delayed emission following triplet formation. However, triplet population under optical excitation is fundamentally limited by the intrinsic intersystem crossing (ISC) efficiency...

Comparison of High‐Sensitivity Troponin T Versus N‐Terminal Pro‐B‐Type Natriuretic Peptide for Prediction of Major Adverse Cardiovascular Events After Noncardiac Surgery

Background Preoperative hs‐TnT (high‐sensitivity cardiac troponin T) and NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) are used for risk prediction in noncardiac surgery. While the European Society of Cardiology recommends hs‐TnT, American Cardiology and European anesthes...

Assessing ethical competence and ethical climate: development and psychometric testing of the Clinical Ethics Support Measurement Instrument (CES-MI)

Abstract Background Clinical ethics support (CES) is increasingly recognised as essential in healthcare, yet its evaluation remains challenging due to the complexity of CES practices and the latent, psychosocial nature of relevant outcomes. The European Moral Case Deliberation Ou...

Metoprolol in Chronic Obstructive Pulmonary Disease without Cardiovascular Disease

BACKGROUND: Beta-blockers may improve outcomes in patients with chronic obstructive pulmonary disease (COPD) without cardiovascular disease, but randomized trials have been inconclusive. METHODS: This was a multicenter, open-label, pragmatic, phase 4 randomized trial. Patients 40...

Digital forensic artefacts in Linux-based Creality 3D printers operating on Klipper firmware: Real-world case studies

The increasing use of 3D printing for illicit manufacturing, particularly of firearm components, presents growing challenges for forensic investigations. This study examines digital forensic (DF) artefacts recovered from two seized Creality 3D printers operating on Klipper firmwa...

Environmental risks of data center infrastructure in Northeastern Brazil from an ecocide risk perspective

Abstract The expansion of data center infrastructure is reshaping global development patterns while intensifying demands for energy, water, and land. Together, these pressures may significantly affect ecosystems, local communities, and sustainable development. This article examin...

Detecting and characterizing restricted diffusion with accessible magnetic field gradients

Abstract For over 50 years, diffusion magnetic resonance (dMR) has been employed in numerous studies on characterizing chemical compounds, porous media, and biological tissues. These studies have almost exclusively employed the Stejskal-Tanner (ST) pulse sequence, which is sensit...