Linköping University

Estimating Abilities With an Elo-Informed Growth Model

Two common methods for modeling abilities that change over time are generalized linear mixed models (GLMMs) and the Elo algorithm. GLMM specifications that avoid assumptions about the shape of the growth curve tend to be computationally heavy. The Elo algorithm is both flexible a...

Can Intraoperative Therapeutic Window Data Predict Chronic Contact Selection in Deep Brain Stimulation?

Abstract Deep brain stimulation (DBS) programming relies on selecting electrode contacts that maximize clinical benefit while minimizing side effects. The therapeutic window (range of current yielding symptom improvement without adverse effects) is a key criterion in this decisio...

Adipose tissue dysfunction in obesity and type 2 diabetes: the role of DNA methylation linking adipogenesis to metabolic disease

Abstract Adipose tissue plasticity, sustained by the recruitment and differentiation of adipocyte precursor cells (APCs), is a key determinant of metabolic health. Failure of this adaptive program, rather than fat mass per se, represents an early contributing factor in the progre...

Bayesian-Guided Cooperative RL Beamforming for Wireless Adversarial User Detection

In next-generation wireless networks, communication systems are expected to go beyond simple data transmission and simultaneously provide high data rates, efficiency, and security. This requirement has motivated the extensive adoption of machine learning methods to develop intell...

The shifting landscape of assessment in STEM education in the age of generative AI

Abstract This article focuses on the impact of generative AI (GenAI) on assessment in STEM education. Guided by the assessment triangle as a conceptual framework, we take an ecosystems perspective to review the extant STEM education literature and identify how GenAI affects what...

Optimal cord blood vitamin D concentration does not protect against type 1 diabetes: a longitudinal cohort study

Abstract Calcidiol (25-hydroxy vitamin D [25(OH)D]) has a putative role in protection against auto-immune diseases, including type 1 diabetes (T1D). However, contradictory findings have been reported. We compared concentrations of the 25(OH)D in cord-blood in 83 children who late...

Coordinating Internal and External HMIs for Cooperative Driver-Pedestrian Situation Resolution

Traffic interactions between vehicles and pedestrians are inherently uncertain due to the dynamic nature of the interaction partners’ behavior. Resolutions require mutual understanding of the situation and each other’s intention, typically achieved through explicit and implicit c...

A Conduction‐Nucleation‐Competition‐Guided 3D Adaptive Gradient Buffer for Dendrite‐Free All‐Solid‐State Lithium Metal Batteries

ABSTRACT The existing designs of buffer for all‐solid‐state Li‐metal batteries (ASSLMBs) are mostly limited to static optimization of single functions and lack systematic regulation of the dynamic competition among ionic conduction, electron distribution, and interfacial lithioph...

A Heterozygous Variant in the GABBR2 Gene in a Girl With Clinical Classic Rett Syndrome

ABSTRACT Background Rett syndrome (RTT) is a neurodevelopmental disorder mainly affecting females and may start with seemingly normal early development but leads to developmental stagnation, regression, and characteristic neurological symptoms. While most cases involve MECP2 vari...

Long-term Trends in Upper Gastrointestinal Bleeding and Ischemic Outcomes after Myocardial Infarction

Abstract Aims Invasive management and intensive antithrombotic regimens have decreased ischemic risk after myocardial infarction (MI) at the cost of more bleeding. Of particular concern is upper gastrointestinal bleeding (UGIB), which is both common and preventable, yet not well...

Which senses do wild vervet monkeys (Chlorocebus pygerythrus) use to evaluate potential food?

Abstract Traditionally, primates have been considered primarily visual animals. However, studies across a variety of taxa suggest that, in the context of food evaluation, reliance on this sense might be more nuanced that previously thought, with dietary specialization and food it...

Sport, exercise, and physical activity in children with cardiovascular disease. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) of the ESC, the Association of Cardiovascular Nursing & Allied Professions (ACNAP) of the ESC, and the Association for European Paediatric and Congenital Cardiology (AEPC)

Regular physical activity offers numerous benefits to children's health and well-being and is essential for reducing cardiovascular risk in children with cardiovascular disease. Despite increasing evidence supporting its benefits, many young patients remain insufficiently active...

Probiotics and Risk of Death, Necrotizing Enterocolitis, and Sepsis in Very Preterm Infants

Importance Probiotics are reported to benefit preterm infants, but population-based clinical evidence is limited. In 2020, the Swedish Neonatal Society issued a national recommendation to supplement very preterm infants (28 weeks 0 days’ to 31 weeks 6 days’ gestation) with probio...

Children’s verbal satiety expressions and caregivers’ responses during preschool mealtimes in Sweden

Abstract Background The development of young children’s recognition and expression of satiety states is an essential part of becoming an independent eater. Children’s ability to self-regulate food intake develops throughout childhood with the support of responsive feeding practic...

Health-related quality of life, psychological well-being and physical activity in patients with mild-to-moderate ascending aortic dilation - a cross-sectional case-control study

Abstract Aim To investigate health-related quality of life (HRQoL), psychological well-being and physical activity in patients with mild-to-moderate ascending aortic dilation. Background While ascending aortic dilation often require lifelong surveillance due to the increased risk...

Sex-specific activity and movement in the threatened marsh fritillary Euphydryas aurinia

Abstract Sex-specific behaviour links environmental conditions to population processes, yet it is rarely quantified in threatened insects. Understanding how the sexes differ in activity and movement matters both for interpreting monitoring data and for habitat management. Here we...

Intersecting governance logics in living labs: beyond governance tensions?

Abstract Living labs are increasingly used to support collaborative experimentation and innovation in urban contexts. However, their integration into established public governance may create tensions between collaborative and traditional governance. This study examines how actors...

Effect of Semaglutide on Thigh Skeletal Muscle Volume, Fat Infiltration and Physical Function in People With Obesity: Secondary Analysis of STEP UP

ABSTRACT Aims To assess the effect of semaglutide on body composition and physical function. Materials and Methods The phase 3b STEP UP trial randomised adults with body mass index ≥ 30 kg/m 2 to once‐weekly subcutaneous semaglutide 7.2 mg, semaglutide 2.4 mg or placebo for 72 we...

Resolving Lateral Heat Transport in GaN‐on‐SiC HEMT Structures via Transient Thermometry

ABSTRACT Understanding lateral heat transport in GaN high‐electron‐mobility transistors (HEMTs) is essential for the thermal management of high‐power and high‐frequency electronics. Here, lateral thermal transport in GaN HEMTs on 4H‐SiC is investigated using electrical thermometr...

Design, Synthesis, and Antimicrobial Activity of Novel Cyt- bd Inhibitors Targeting Energy Compensation in Mycobacterium tuberculosis

Abstract Drug-resistant Mycobacterium tuberculosis (Mtb) poses a growing threat, necessitating new therapeutic strategies. The cytochrome bcc-aa3 oxidase (Cyt-bcc) is an attractive target, yet single-agent inhibition fails owing to compensation by the alternative cytochrome bd te...