La Trobe University

Non-asymptotic oracle inequalities for the Lasso in high-dimensional mixture of experts

Abstract We study Lasso estimation for high-dimensional softmax-gated Gaussian mixture-of-experts (SGMoE) regression models, where the predictor dimension P may exceed the sample size N . Under bounded parameters, we establish a non-asymptotic Kullback–Leibler (KL) oracle inequal...

Physical, Volatile, and Flavour Precursor Changes in Faba Bean During Rhizopus oryzae Fermentation

Faba bean (Vicia faba L.) is increasingly recognised as a nutritious and sustainable food ingredient, although its characteristic beany and green odours can limit consumer acceptance. Fermentation offers a potential strategy to modify the sensory and functional properties of legu...

Clinical examination findings were not associated with isometric strength or functional performance in adults with groin pain

Abstract Objectives The aim of this study was to investigate whether positive clinical examination findings were associated with selected measures of lower-limb isometric strength or functional performance in physically active adults with groin pain. Methods This was a cross-sect...

Net carbon emission accounts, drivers, and mitigation measures in China, 1980–2020

Mitigating net CO 2 emissions under socioeconomic development and climate variability is essential for climate action and sustainable development goals. Here, focusing on anthropogenic emissions and terrestrial ecosystem sinks, we construct a national-scale account of China's net...

In Vivo Blood Kinetics and Transcript Integrity of Three mRNA–Lipid Nanoparticle Vaccines in Humans

Abstract mRNA–lipid nanoparticle (LNP) vaccines are detectable in human blood after vaccination, but platform-specific differences in systemic persistence and transcript integrity remain poorly defined. We analyzed serial blood samples from 73 participants receiving Moderna mRNA-...

Evaluating the impact of triple-drug mass drug administration using human and mosquito-based indicators of lymphatic filariasis in Samoa, 2019 – 2024

Background For lymphatic filariasis (LF) elimination, the World Health Organization recommends multiple rounds of mass drug administration (MDA) to interrupt transmission. While LF antigen (Ag) is routinely used to monitor progress, recent evidence suggests more time-sensitive in...

Waste reduction semiotics: Their significance and communication for cleaner production

The waste crisis in Australia exacerbates, yet efforts to boost recycling rates remain inadequate. Practically and academically, recycling is to be enhanced by the respective recycle signs on packaging; however, the true effectiveness of signs and their levels of interpretation a...

Mapping the Silence: Cross-Lingual Asymmetries in Large Language Model Refusal and Evasion on Sensitive History

As large language models increasingly shape public discourse, this study evaluates how US and China-based models govern access to politically sensitive history in US English and Mandarin Chinese. Across 2,400 interactions covering sixty globally significant events, we examined ho...

An Exploratory Study of ABT-806, a Tumor-Specific Anti-EGFR Antibody, in Subjects with Recurrent or Metastatic Head and Neck and Other Squamous Cell Carcinomas

Introduction: Despite their benefit, current anti-EGFR therapies are limited by narrow efficacy profiles due to dose-limiting toxicities. This phase 2 open-label study evaluated the efficacy and safety of ABT-806, an EGFR-targeting antibody that is tumor specific, in patients wit...

Where are my dragon scats? Victorian grassland earless dragon scat persistence and detection dog-handler team search efficiency

Context Reptile species are declining globally, but low detection success is a challenge for reptile monitoring. The Victorian grassland earless dragon (Tympanocryptis pinguicolla; VGED) is the most imperilled reptile in Australia and faces immediate threats from habitat destruct...

Chronic pain treatment experiences and barriers among opioid agonist treatment participants who inject drugs: A qualitative study

Abstract Background and aim Co‐occurring chronic pain affects nearly half of people receiving opioid use disorder (OUD) treatment. Although this pain is often severe, it is usually inadequately managed. Stigma and clinical complexity associated with OUD are thought to further res...

Somatosensory processing is altered in people with hip osteoarthritis compared to controls: A cross-sectional study

Background With knee osteoarthritis (OA), measures of mechanical and thermal pain sensitivity relate to both pain severity and treatment outcomes, and lower limb left/right judgement is impaired. However, little is known about these somatosensory variables in people with hip OA....

A descriptor-driven framework for SiNx:H in crystalline silicon solar cells: linking bonding configuration to device performance and reliability

Hydrogenated silicon nitride (SiN x :H) is a cornerstone material in crystalline silicon photovoltaics, simultaneously providing antireflection functionality and defect passivation. However, these roles are typically treated independently, limiting predictive optimization, partic...

The circulating lipidome in severe obesity

Severe obesity (SevO; BMI ≥ 40 kg/m 2 ) is rising globally yet remains understudied mechanistically. To characterize lipidomic alterations at the species level, we analyzed Border Health Research Cohort participants with fasting plasma lipidomics and genetic data, comparing SevO...

Spatio-Temporal Statistical Assessment of Water Quality Dynamics in the Kelani River, Sri Lanka: A Data-Driven Framework for Sustainable River Basin Management

The Kelani River is one of the most important freshwater resources in Sri Lanka, supplying drinking water, supporting aquatic ecosystems, and sustaining industrial and agricultural activities. However, increasing anthropogenic pressures have intensified the need for comprehensive...

Regulatory Policy Changes and Mifepristone Access Through Pharmacies in Australia

Importance In an effort to improve access, the Australian Therapeutic Goods Administration lifted prescribing and dispensing restrictions on mifepristone in August 2023. Mifepristone is approved for medication abortion up to 63 days’ gestation and is marketed in Australia in a co...

The Unique Role of Mental Health Nurse Practitioners to Improve Healthcare Access: A Qualitative Study

The prevalence of mental health and substance use disorders is growing in Aotearoa New Zealand, with rising unmet need and health services under immense pressure. Nurse practitioners (NPs) have the potential to transform healthcare delivery and improve healthcare access and healt...

‘Got to be the right fit, the right connection’: a scoping review of the peer support experiences and perspectives of adults with acquired neurological disability

BACKGROUND: Peer support for people with acquired neurological disability is gaining worldwide popularity, yet it is conceptually unclear what constitutes valuable peer interactions. To build a greater understanding from the lived experience perspective, this scoping review synth...

Workplace management of musculoskeletal and mental health risks: translating evidence into practice

There is a large body of research evidence identifying the biomechanical and psychosocial hazards that can affect work-related musculoskeletal disorders (MSDs) and stress-related mental health problems (MHPs). The APHIRM Toolkit was developed to facilitate more effective translat...

How does apartment living shape public transport travel? Insights from interviews with apartment residents in Melbourne, Australia

Apartment housing, as part of compact city policies, has been promoted to encourage greater public transport use. While the determinants of public transport use are well documented, less attention has been given to how these determinants are encountered, internalised, and respond...