Kyushu University

Differential Models of Time-Variant Tumor Growth Trajectories with Sensitive, Persister, Resistant Cell Population in Lung Tumors During Tyrosine Kinase Inhibitor Therapy

Modeling the dynamics of three tumor cell populations, i.e., sensitive, persister, and resistant tumor cells, during molecularly targeted therapy with tyrosine kinase inhibitors (TKIs) would be valuable for adjusting treatment plans for patients with epidermal growth factor recep...

Trade-off between repository footprint and radiotoxicity in geological disposal of vitrified high-level waste from spent MOX fuels: quantitative assessment of simplified minor actinide separation

Radioactive waste management remains a critical challenge for the sustainability of nuclear energy systems, particularly for closed fuel cycles utilizing mixed oxide (MOX) fuel. MOX fuel contains significantly higher concentrations of minor actinides (MAs) and heat-generating nuc...

Monitoring pedestrian walking dynamics under environmental and policy influences in urban spaces

Abstract Understanding how environmental conditions and policy interventions jointly shape pedestrian mobility is essential for designing resilient, adaptive, and human-centered urban spaces. This study presents a computer-vision framework that extracts pedestrian trajectories fr...