Kyungpook National University

Neuroprotective Potential of Xanthoceras sorbifolium Seed Oil: GC-MS Profiling and Fatty Acid-Binding Protein 7-Targeted Computational Modeling

This study investigated the neuroprotective potential of Xanthoceras sorbifolium Bunge (XSB) seed oil through fatty acid profiling, antioxidant assays, and in silico targeting of FABP7. Among the solvent-to-solid ratios tested, 1:20 (w/v) gave the highest oil yield (72.91%) and t...

The Chronic Psychological Burden of Urban Noise and Light Pollution: A Cross-Sectional Study of a Major Crossroads in Daegu, South Korea

Background: Residential environmental stressors, such as noise and light pollution, significantly impact psychological well-being.While individual sensitivity and cognitive perception are known to influence environmental annoyance, how these factors operate differently across aud...

Buffering digital risk: the moderating role of education in the ICT–suicide mortality interface

The expansion of education and the rapid advancement of Information and Communication Technology (ICT) have fundamentally reshaped the socioeconomic determinants of mental health. However, the complex interplay between these two forces in shaping suicidal behavior remains underex...

Dual-mode SOX2 regulation by miR-150 via mRNA suppression and autophagy controls stem cell fate

Autophagy plays a critical role in maintaining cellular homeostasis and regulating stem cell fate. Although microRNAs (miRNAs) are being increasingly recognized for their ability to modulate autophagy and pluripotency in human pluripotent stem cells (hPSCs), the underlying molecu...

Withdrawal period estimation of a long-acting intramuscular amoxicillin trihydrate–florfenicol combination in olive flounder

This study aimed to scientifically validate the withdrawal periods (WPs) of a long-acting intramuscular formulation of amoxicillin trihydrate (AMXT) and florfenicol (FFC) in olive flounder (Paralichthys olivaceus). WP estimates from the European Medicines Agency (EMA) and U.S. Fo...

165 Astrocyte–Glioblastoma Metabolic Interactions at the Invasive Margin Reveal Therapeutic Vulnerabilities

Abstract Introduction Glioblastoma is an aggressive brain tumour that, despite multimodal treatment, almost always recurs. Infiltrative tumour cells within the brain microenvironment are thought to drive recurrence and are supported by surrounding non-cancerous brain cells. Among...

Synthesis of Chalcone‐Sulfonamide Hybrids as Antibacterial, Antioxidant, and Anti‐Inflammatory Agents With Comprehensive In Silico and ADMET Profiling

Chalcone‐sulfonamide hybrids ( 12a–h ) were synthesized via Claisen–Schmidt condensation in good yields (64%–83%) and confirmed by NMR spectroscopy. The compounds exhibited moderate to good antibacterial activity against Gram‐negative ( Escherichia coli , Pseudomonas aeruginosa )...

Spatial accuracy and clinical feasibility of CT/US fusion imaging for hepatic interventions in dogs

Computed tomography (CT)–ultrasound (US) fusion imaging is widely used for hepatic interventions in human medicine, but its technical performance has not been evaluated in dogs. This study assessed the spatial accuracy, fusion time, and image quality of CT/US fusion imaging in th...

P1.045. Management of a Large Esophagojejunostomy Defect After Laparoscopic Total Gastrectomy Using Endoscopic Vacuum Therapy and Adjunctive Stenting

Abstract Topic Benign Disease: Other Background Esophagojejunostomy (EJ) leakage after total gastrectomy remains a life-threatening complication. While endoscopic vacuum therapy (EVT) has emerged as an effective treatment option, management of large anastomotic disruption and sub...

Urinary Extracellular Vesicles as a Source of Biomarkers for Kidney Allograft Rejection: A Systematic Review

BACKGROUND: Kidney transplant rejection remains a leading cause of graft loss, and diagnosis still depends largely on invasive biopsies. Urinary extracellular vesicles (uEVs) offer a potential noninvasive alternative for detecting allograft rejection through molecular profiling o...

Determining the optimal design characteristics of trapezoidal piano key weirs for improved water discharge

Abstract This study attempts to evaluate the influence of design factors and flow characteristics on the discharge capacity of trapezoidal piano key weirs. To evaluate the influence of the main design factors on discharge rates, 9 models were simulated, with width ratios of 1.25,...

Impact of a prolonged nationwide residents’ strike on acute ischemic stroke care in a metropolitan city

Abstract BackgroundAcute ischemic stroke (AIS) requires timely management in both prehospital and in-hospital phases to optimize outcomes. In 2024, South Korea experienced a prolonged nationwide residents’ strike that disrupted the healthcare system, potentially affecting AIS man...

Myoglianin coordinates hormonal and nutrient signaling to control metamorphosis and tissue growth in the fall armyworm

The transition from larval to pupal stage in holometabolous insects is a critical developmental decision regulated by hormonal and nutritional cues. The studies reported here revealed a central role for the TGF-β ligand Myoglianin (Myo) in integrating these signals in a major lep...

Moment Matching for Bayesian Inference in the Baseline New Keynesian Model

Abstract The sparsity and small size of economic samples often obscure the identification of parameters in macroeconomic models. These identification problems originate from the poorly defined mapping between a structural model and reduced-form parameters. Hence, researchers rely...

Photoacoustic Tomography with Time-Dependent Damping: Theoretical and a Convolutional Neural Network-Guided Numerical Inversion Procedure

Abstract. In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to the absorbed optical energy, wh...

Influence of many-body correlation and mixed-valence fluctuations on X-ray magnetic circular dichroism and resonant inelastic X-ray scattering spectra

X-ray magnetic circular dichroism (XMCD) and resonant inelastic X-ray scattering with magnetic circular dichroism (RIXS-MCD) provide unparalleled insights into the electronic and magnetic dynamics of complex materials. However, interpreting their spectra in mixed-valence systems...

Optimal control strategies for dengue transmission under varying adult prevalence of Wolbachia -carrying mosquitoes: a deterministic mathematical modeling study

Objectives: This study aimed to develop prevalence-informed post-release dengue control strategies for settings in which Wolbachia-carrying Aedes aegypti mosquitoes have become established through population replacement and to quantify how optimal supplementary intervention inten...

Age-Stratified Outcomes of Off-Clamp Robot-Assisted Partial Nephrectomy: A Comparison of Patients Younger Than 65 Years and Those Aged 65 Years or Older

Background: Evidence for completely off-clamp robot-assisted partial nephrectomy (RAPN) in older patients is limited. We compared age-stratified short-term outcomes. Methods: We reviewed 146 consecutive patients who underwent off-clamp RAPN between June 2022 and March 2026: 99 we...

Clinical Characteristics and Outcomes of Pediatric Patients With Long QT Syndrome: A Korean Multicenter Cohort Study

This multicenter nationwide cohort study comprehensively analyzed the clinical features, genetic architecture, and outcomes of Korean pediatric patients with long QT syndrome (LQTS).Prolonged QT intervals, fetal arrhythmia, and LQT2/3 genotypes compared to LQT1 were independent r...

Effect of visual stimulation on quantitative light-touch assessment using the active von Frey filament test

Quantitative assessment of light-touch sensation is essential in the evaluation of peripheral nerve disorders. Although the active von Frey filament test (AvF) provides objective and continuous tactile threshold measurements, the influence of testing conditions on AvF values rema...