Kyungpook National University Hospital

Time-step level sleep apnea detection using LSTM with adaptive thresholding in polysomnography

Sleep apnea is a prevalent disorder linked to severe health risks. Current diagnosis relies on manual polysomnographic (PSG) analysis, which is time-consuming and subjective. This study aims to develop an objective, automated framework for time-step level apnea detection. We prop...

Association of Estimated Arterial Stiffness with Collateral Status and Functional Outcome after Endovascular Thrombectomy: A Secondary Analysis of the OPTIMAL-BP Trial

PURPOSE: Estimated pulse wave velocity (ePWV) is a surrogate of arterial stiffness that may influence stroke outcomes and potentially affect collateral circulation. We examined the association of ePWV with collateral status and 3-month functional outcome after successful endovasc...

ARNAI: Artifact Removal Network Based on Autoencoding and Inpainting for Robust Spinal Image Segmentation and Measurement

Purpose To develop an artificial intelligence framework, robust to spinal implants, for automated measurement of spinopelvic parameters on postoperative radiographs. Materials and Methods Lateral lumbar spine radiographs from two institutions (internal dataset [ n = 2486]: Januar...

Network Structure and Central Symptoms of Depression in Older Korean Adults: A Community-Based Analysis

Objective This study aimed to investigate the network structure of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV)-defined depressive symptoms in a large, community-dwelling sample of older Korean adults, to better understand symptom interrelationsh...

Comparative study on the clinical effectiveness of low-concentration cyclosporine eye drops in patients with dry eye disease

Purpose This study aimed to evaluate the efficacy and safety of low-concentration, nanoparticle-based cyclosporine eye drops (SCAI-001 0.01% and SCAI-001 0.02%) compared to those of the conventional Restasis ® (cyclosporine 0.05%) emulsion for dry eye disease (DED). Methods In th...

Prognostic implications of the duration of continuous kidney replacement therapy in 3-month survivors of acute kidney injury: findings from the LINKA cohort

The duration of continuous kidney replacement therapy (CKRT) represents a complex clinical surrogate reflecting the severity of systemic illness, the rate of metabolic recovery, and clinical decision-making regarding treatment discontinuation. The effect of CKRT duration on long-...

Anomaly Localization and Classification of Jaw Cysts and Tumours Using Anatomy-Conditioned Diffusion on Panoramic Radiographs

Objectives Accurate localization and classification of jaw cysts and tumours on panoramic radiographs are important for timely referral and treatment planning but remain challenging due to overlapping anatomy, heterogeneous lesion appearances, and dental restorations. This study...

Discordant Antitumor Efficacy with Compromised Survival in High-Risk Unresectable Hepatocellular Carcinoma

Background/Objectives: Real-world data in high-risk patients remain limited; this study evaluated survival, safety, and prognostic factors in this patient group. Methods: This multicenter study retrospectively reviewed 783 patients who received Ate/Bev from 2022–2024 across South...

Age- and sex-adjusted genomic differences between Korean and Beat AML cohorts

Genomic profiling plays a central role in risk stratification and therapeutic decision-making in acute myeloid leukemia (AML), yet the clinical implications of population-specific genomic architectures remain incompletely defined. We conducted a prospective, multicenter study of...

Preferences and reasons for clothing colors in women patients and survivors of breast cancer in Korea

Purpose Clothing color can affect the psychological aspects in female patients and survivors of breast cancer; however, little is known regarding their preferences and reasons for choosing specific clothing color. This study aimed to explore the factors influencing their clothing...

Changing Clinical Characteristics, Diagnostic Patterns, and Outcomes of Tuberculosis in South Korea: The Korean Tuberculosis Cohort, 2019-2024

BACKGROUND: Tuberculosis (TB) remains a public health concern in South Korea despite declining national notifications. We evaluated temporal changes in clinical characteristics, diagnostic patterns, and treatment outcomes in the Korean Tuberculosis Cohort (KTBC) from 2019 to 2024...

Aging Biology of Bone-to-Tendon Healing and the Epigenetic Clock: A Biological-Age Readout of Rotator Cuff Healing Capacity

The “unexplained failure” of rotator cuff repair is multifactorial, but its structural endpoint is anatomically consistent, i.e., the failure of the tendon-to-bone interface (enthesis) to heal. The native enthesis is a four-zone fibrocartilaginous gradient that does not regenerat...

Successful Management of Ultra-high-risk Mixed Ovarian Germ Cell Tumor Using a Pediatric-inspired Intensive Chemotherapy Regimen: A Case Report

Background/Aim: Non-gestational ovarian choriocarcinoma is an extremely aggressive malignancy with limited standardized treatment protocols. We present a successful multidisciplinary approach for a high-risk mixed malignant ovarian germ cell tumor (MOGCT) containing a predominant...

P1.045. Management of a Large Esophagojejunostomy Defect After Laparoscopic Total Gastrectomy Using Endoscopic Vacuum Therapy and Adjunctive Stenting

Abstract Topic Benign Disease: Other Background Esophagojejunostomy (EJ) leakage after total gastrectomy remains a life-threatening complication. While endoscopic vacuum therapy (EVT) has emerged as an effective treatment option, management of large anastomotic disruption and sub...

Impact of a prolonged nationwide residents’ strike on acute ischemic stroke care in a metropolitan city

Abstract BackgroundAcute ischemic stroke (AIS) requires timely management in both prehospital and in-hospital phases to optimize outcomes. In 2024, South Korea experienced a prolonged nationwide residents’ strike that disrupted the healthcare system, potentially affecting AIS man...

Effect of visual stimulation on quantitative light-touch assessment using the active von Frey filament test

Quantitative assessment of light-touch sensation is essential in the evaluation of peripheral nerve disorders. Although the active von Frey filament test (AvF) provides objective and continuous tactile threshold measurements, the influence of testing conditions on AvF values rema...

Late-onset infective endocarditis after transcatheter atrial septal defect device closure involving mechanical factors: a case report

Late-onset infective endocarditis after transcatheter atrial septal defect device closure is uncommon, and in selected patients, mechanical factors related to adverse device-tissue interaction may contribute to the development of late device-related infection. A 15-year-old boy p...