Kent Hastanesi

Vitamin A and D Status, Selected Genetic Variants, and Allergy-Related Phenotypes: An Exploratory Retrospective Study

Background/Objectives: Vitamins A and D are critical regulators of immune function, and genetic variation in their metabolic pathways may influence vitamin status and immune responses. This study investigated the combined nutrigenetic roles of vitamins A and D and their associati...

Hierarchical diffusion-guided consistency learning framework for knee anterior cruciate ligament classification

Anterior cruciate ligament (ACL) classification in knee magnetic resonance imaging (MRI) is challenging due to diagnostic evidence being dispersed across multiple slices and anatomical supervision often being sparse. We propose a three-stage hierarchical diffusion-guided consiste...

Development and Psychometric Evaluation of the Peritoneal Dialysis Treatment Adherence Scale: A Multicenter Methodological Study

Background/Objectives: Peritoneal dialysis (PD) requires patients to manage dialysis procedures, medications, fluid intake, and nutrition at home. Existing assessment approaches do not adequately distinguish patients’ treatment-related knowledge and awareness from their self-repo...

Bracing in adult scoliosis: a scoping review of clinical outcomes

Bracing is commonly used as a conservative treatment for scoliosis, but its effects in adults with scoliosis remain unclear. To map and synthesize the existing evidence on the effects of bracing in adults with scoliosis, focusing on radiological outcomes, pain, physical function,...

Percussive Vibration Therapy as an Adjunct to Conventional Physiotherapy in Chronic Non-Specific Low Back Pain: A Randomized Controlled Trial

Background/Objectives: Hand-held percussive vibration therapy (PVT) is widely used in musculoskeletal rehabilitation, yet its incremental benefit beyond an active physiotherapy program for chronic non-specific low back pain (CNLBP) is unclear. We investigated whether PVT added to...

Turkish Adaptation of the Clean Food Consumerism Scale: A Validity and Reliability Study

Background: Clean food consumerism reflects consumers’ preferences for foods perceived as natural, authentic, transparent, and health-promoting. This study aimed to culturally adapt the Clean Food Consumerism Scale (CFCS) into Turkish and evaluate its psychometric properties. Met...

Quality Evaluation of Commercial Products Marketed as Thymus vulgaris L. Essential Oil According to European Pharmacopoeia 10.0 Criteria

Essential oils are mixtures of complex secondary metabolites with variable chemical compositions that determine their therapeutic effects. Thyme oil, obtained from the fresh or dried leaves and flowers of Thymus spp. through steam distillation, is widely used in food, pharmacy, a...

Management of Type 2 Diabetes, 2026. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the consensus statement on the management of type 2 diabetes in nonpregnant adults, published since 2006 and last updated in 2022. The target audience is the multid...

Climate change education in undergraduate medical faculties in Türkiye: a national descriptive cross-sectional study

Climate change is increasingly recognized as a critical threat to global health, with growing implications for clinical practice, health systems, and medical education. Medical professionals are expected not only to understand the health effects of climate change but also to enga...

Upfront surgery vs. neoadjuvant therapy in pancreatic cancer with venous involvement: a multicenter retrospective analysis

Abstract Introduction The benefits of neoadjuvant therapy (NAT) for pancreatic cancer (PC) with portal venous involvement remain debated. This study aimed to compare the short- and long-term outcomes of surgery with or without NAT in patients with PC with suspected venous involve...

Delivering the EU Safe Hearts Plan: the essential role of laboratory medicine in cardiovascular health

Abstract The European Union Safe Hearts Plan provides an opportunity to strengthen cardiovascular prevention, early detection, treatment, and monitoring across Europe. This EFLM position paper argues that laboratory medicine must be recognized as a central component of its implem...

Psychological Well-Being, Dispositional Hope, and Contentment with Life Among Public Hospital Physicians in Türkiye’s Black Sea Region: A Cross-Sectional Study

Background: Physicians work under demanding conditions that may affect their psychological functioning and evaluations of life. Positive psychological resources, particularly dispositional hope, may be relevant to the association between psychological well-being and contentment w...

From Germinated Pseudocereals to Functionalized Bread: The Role of the Food Matrix in Protein and Phenolic Bioaccessibility

Despite the well-documented nutritional benefits of germinated pseudocereals, whether these benefits are preserved following bread incorporation remains unexplored. Bread incorporating germinated quinoa, amaranth, and buckwheat at 15% and 30% substitution was evaluated alongside...

Incidental/Misdiagnosed Intrahepatic Cholangiocarcinoma and Combined Hepatocellular-Cholangiocarcinoma in Patients Undergoing Living Donor Liver Transplantation

Background/Objectives: Mixed hepatocellular-cholangiocarcinoma and intrahepatic cholangiocarcinoma (CCA) are increasingly reported in patients with cirrhosis. Traditionally, these tumor types have not been considered indications for liver transplantation. We aimed to present our...

Clinical Outcomes of Robotic and Laparoscopic Ileal Pouch–Anal Anastomosis in Ulcerative Colitis: A Retrospective Cohort from Two Tertiary Referral Centers

Background: Robotic platforms may facilitate the technically demanding pelvic and multiquadrant components of ileal pouch-anal anastomosis (IPAA), but comparative evidence remains limited. Methods: We retrospectively compared 90-day outcomes after robotic ( n = 36) and laparoscop...

Gender‐Specific Cancer‐Related Survival Analysis of Robotic Versus Laparoscopic Low Anterior Resection for Rectal Adenocarcinoma: A Multicenter Study

ABSTRACT Aim This study compared short‐ and long‐term outcomes of robotic and laparoscopic low anterior resection (LAR) for rectal adenocarcinoma using sex‐stratified analyses. Methods Patients who underwent elective robotic or laparoscopic LAR for rectal cancer were included. Pr...

In Vitro Biological Properties of Thiazole-Containing Cobalt(II) and Copper(II) Phthalocyanines: DNA Cleavage, Antioxidant, Antimicrobial, Antibiofilm, and Surface Anti-Escherichia coli Activities

Background/Objectives: Given the excellent biochemical and optical properties of phthalocyanines, this study aims to develop new phthalocyanine-based bioagents for multidisciplinary applications. Methods: 3-((4-(4-fluorophenyl)thiazol-2-yl)thio)phthalonitrile was synthesized by c...

Clinical Characteristics and Thyroid Findings in Children with Isolated Premature Adrenarche

Objectives: Premature adrenarche (PA) is associated with accelerated adrenal maturation, but data regarding thyroid characteristics in children with isolated PA are limited. We aimed to describe the clinical features of children with idiopathic PA and investigate the relationship...

Epigallocatechin Gallate Modulates the Cellular Response to Doxorubicin in HeLa Cervical Cancer Cells

Cervical cancer remains a major cause of cancer-related mortality worldwide, highlighting the need for strategies that may improve responses to conventional chemotherapeutics. Epigallocatechin gallate (EGCG), a green-tea polyphenol with diverse biological activities, has been inv...

Ustekinumab as an Effective Therapeutic Option in Papillon–Lefèvre Syndrome: Long‐Term Follow‐Up

Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive genodermatosis characterized by palmoplantar hyperkeratosis and severe periodontitis, leading to premature loss of both primary and permanent teeth, and treatment responses are often unsatisfactory. We report a 20-year...