Karadeniz Technical University

The Role of Immature Granulocyte Count and Percentage as Novel Indicators of Systemic Inflammation in Plaque Psoriasis

Background/Objective: Psoriasis is a chronic immune-mediated inflammatory disease with systemic involvement. Immature granulocytes (IGs) are potential inflammatory markers, but their role in psoriasis is unclear. We evaluated immature granulocyte count (IG#) and percentage (IG%)...

Exploring Trade-offs Between Carbon Storage and Timber Production with Alternative Rotation and Harvest Policies: Insights from a Real-World Forest Management Area

Forests provide essential ecosystem services, particularly timber production and carbon sequestration, both of which play critical roles in climate change mitigation and sustainable forest management. However, the long-term consequences of alternative management strategies on car...

Blood Pressure and Angina-Related Health Status During Benidipine Therapy: A Multicenter Real-World Cohort Study

Background: Benidipine is a long-acting calcium channel blocker used for the treatment of hypertension and chronic coronary syndrome. Although it effectively lowers blood pressure (BP), the relationship between BP reduction and improvement in angina-related health status during b...

Knowledge, attitudes, and use of artificial intelligence among adult and pediatric hematologists in Türkiye: a national cross-sectional survey

Artificial intelligence (AI), including generative AI and large language models, is entering hematology practice and research, but real-world integration depends on clinicians’ knowledge, attitudes, use, and governance rather than algorithm performance alone. Evidence specific to...

Reduced Vagal Compound Action Potential Amplitude Is Associated with Glomerular Injury in an Experimental Rabbit Model of Severe Subarachnoid Hemorrhage

Background: Subarachnoid hemorrhage (SAH) induces a sympathetic surge and systemic inflammation that may impair renal perfusion and glomerular integrity. Although the vagus nerve is central to autonomic and anti-inflammatory regulation, its relationship to renal structural injury...

Determination of main components by capillary electrophoresis and antioxidant activities in anatolian royal jellies: discrimination by principal component analysis

Royal jelly (RJ), a secretion of worker honey bees, is a nutritionally valuable bee product known for its bioactive properties. Different regions offer distinct floral sources that bees feed on, resulting in a unique composition of the RJ they produce. Moreover, certain component...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...

Prognostic impact of pathological complete response in hormone receptor–positive/HER2-negative breast cancer treated with neoadjuvant chemotherapy: a multicenter cohort study

Pathological complete response (pCR) is an established surrogate endpoint in aggressive breast cancer subtypes; however, its prognostic role in hormone receptor (HR)-positive/HER2-negative disease remains controversial. We aimed to evaluate clinicopathological predictors of pCR a...