Kangwon National University

SimpleMicrobiome: An integrated web-based platform for streamlined microbiome data analysis and visualization

Microbiome studies require multiple analytical steps after initial sequence processing. These steps commonly include data harmonization, preprocessing, taxonomic profiling, diversity analysis, differential abundance testing, predictive modeling, network inference, and preparation...

Navigating hyperreality: Tourism practitioners’ ethical sense-making of deepfake destination advertising

While deepfake technology is rapidly transforming destination marketing, scholarship on this topic remains predominantly consumer-centric, obscuring how practitioners interpret and manage these hyperreal representations. To address this gap, the purpose of this study is to explor...

Population heterogeneity in Helicobacter pylori PMSS1 shapes variable mouse infectivity: derivation of the homogeneous reference strain PMSS2

ABSTRACT Experimental infection models are widely used to investigate host–microbe interactions, often under the assumption that bacterial populations are genetically uniform. Here, we examined population heterogeneity in the widely used Helicobacter pylori strain PMSS1 and its r...

Current legislation and recommendations on ethical post-experimental care and disposition of laboratory animals: a call for global standards

The fate of laboratory animals once experiments end remains an ethical blind spot. This Comment compares the legislation governing the post-experimental care and disposition of laboratory animals—rehoming, reuse, setting free and tissue sharing—across the European Union, USA, UK...

Oral Health Indicators as Important Predictors of Frailty in Korean Adults Aged 50 Years and Older: A Sex-Stratified Explainable Machine Learning Approach

Background Frailty is a major public health concern, yet oral health indicators are rarely incorporated into prediction models. Objective To develop sex-stratified explainable machine-learning models for frailty prediction. Methods Cross-sectional data from 12,302 adults aged ≥50...

AI Accelerated Chemical Screening Integrates ChemBERTa to Identify Repositionable CASP4 Inhibitors via MD Simulations and MM/PBSA Analysis

Abstract This study employed an integrated ligand-based virtual screening pipeline to identify potential CASP4 inhibitors from the DrugBank database, leveraging docking-score prioritization, SMILES-derived ChemBERTa embeddings, and key physicochemical descriptors. Building on thi...

Analysis of the role experiences of clinical nurse educators in the process of improving the nursing education system

With the recent increase in critically ill patients and the ongoing process of healthcare system reform, the training of nurses capable of caring for critically ill patients and the securement of a stable nursing workforce have become emphasized as important social tasks. To addr...

Three-Year Outcomes of Drug-Eluting Stents, Drug-Coated Balloons, and Non-Drug-Eluting Devices in Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry

Background: Although drug-eluting devices have demonstrated improved efficacy in femoropopliteal artery (FPA) disease, evidence on their long-term clinical outcomes in realworld practice remains limited.Methods: Using data from the multicenter Korean Vascular Intervention Society...

Genetic mutations driving ciprofloxacin resistance in laboratory-evolved Salmonella Typhimurium

ABSTRACT Ciprofloxacin resistance in Salmonella Typhimurium is a significant public health concern, and the mechanisms by which the resistance evolves are poorly defined. Here, by serial passaging under antibiotic selection, we isolated ciprofloxacin-resistant S . Typhimurium mut...

Unwinding together: a case study of consumer cooperative dissolution in South Korea as a collective, complex process

Purpose This paper aims to analyze how H1 Coop enacted and shaped its cooperative way of closure through the concepts of translation and performativity. Furthermore, by connecting translation and performativity with practice theory, the study highlights how H1 Coop’s distinctive...

Repurposing irosustat for malaria: host-targeted antiplasmodial activity via cholesterol sulfate modulation against drug-resistant Plasmodium falciparum

Abstract Background The urgent global need for novel antimalarial drugs targeting Plasmodium falciparum has intensified due to rising mortality and drug resistance. This study examines a host-directed strategy targeting lipid metabolism by evaluating the antiplasmodial activity o...

Mechanical performance of polyvinyl alcohol macrofiber‐reinforced very‐early‐strength latex‐modified concrete for early‐opening pavement repair

Abstract Very‐early‐strength latex‐modified concrete (VES‐LMC) is widely used for emergency pavement repairs requiring rapid opening to traffic; however, improving mechanical performance while maintaining early‐age strength remains a challenge. This study evaluates the effectiven...

Clinical Setting-Based Medical Care of Transgender and Gender-Diverse Individuals in East Asia: A Scoping Review

Purpose:Transgender and gender-diverse (TGD) individuals in East Asia face significant structural barriers in health care utilization, yet systematic evidence focusing on clinical delivery remains scarce. This scoping review mapped available evidence on clinical setting-based med...

First-scoring patterns associated with winning in Taekwondo Kyorugi under the best-of-three system: A sequential pattern mining approach

This study examined first-scoring patterns associated with winning in Taekwondo kyorugi under the best-of-three (Bo3) system using sequential pattern mining. A total of 545 matches were analyzed according to sex and weight categories. Match events were categorized according to ro...

Dual-mode SOX2 regulation by miR-150 via mRNA suppression and autophagy controls stem cell fate

Autophagy plays a critical role in maintaining cellular homeostasis and regulating stem cell fate. Although microRNAs (miRNAs) are being increasingly recognized for their ability to modulate autophagy and pluripotency in human pluripotent stem cells (hPSCs), the underlying molecu...

Analysing Urban Environmental Dynamics through Multi-Sensor Remote Sensing and Deep Learning: An Integrated Classification-Regression Framework

Urban centers worldwide are facing changes in terms of environmental standards and an increase in temperatures.Recent significant developments, particularly in developing nations, have led to an increase in Land Surface Temperature (LST) and surface thermal variations in urban ar...

Farm-Gate Prices as an Economic Signal of Foot-and-Mouth Disease Vaccination Performance in Hanwoo Cattle: A Nationwide Time-Lag Analysis

Background/Objectives: In mandatory livestock vaccination programs, post-vaccination immunity depends on both vaccine characteristics and consistent on-farm implementation. We evaluated whether Hanwoo farm-gate prices were temporally associated with subsequent foot-and-mouth dise...

Domain-Specific Cognitive Concordance in Older Married Couples

Importance Spousal similarity in late-life cognition has been reported, but whether concordance differs across cognitive domains remains unclear. Objective To examine whether cognitive concordance among older married couples is domain specific by comparing real couples with demog...

Optimizing drip irrigation density enhances growth, yield, physiology, and antioxidant capacity of Korean strawberry ‘Kuemsil’ in recycling hydroponics

Efficient irrigation management is crucial for improving water-use efficiency and maintaining high productivity in controlled-environment strawberry cultivation. This study evaluated how different drip irrigation densities influence the growth, physiological responses, yield, fru...

Application of Fibronectin-Coated Microparticles for Isolation of Human iPSC-Derived MSCs

Abstract BACKGROUND : Bone marrow–derived MSCs (BMMSCs) are limited by availability, donor variability, and age-related decline, highlighting the need for alternative MSC sources. Induced pluripotent stem cells (iPSCs) offer a scalable solution. This study introduces a novel thre...