Institution
Kangwon National University
Recent research
- BiologyOpen access
Emerging paradigms in systemic immunology have illuminated the intricate, bidirectional communication networks linking distant organ systems, which are conceptualized as the gut–lung–brain axis. The homeostasis of this anatomical triad is primarily disrupted by localized and syst...
- Health & MedicineOpen access
Trypanosoma brucei, the protozoan parasite responsible for African trypanosomiasis, undergoes a divergent cell cycle characterized by closed mitosis, inheritance of single-copy organelles such as the kinetoplast, basal body, and flagellum, and anterior-to-posterior longitudinal c...
- BiologyOpen access
Stress-induced eIF2α phosphorylation promotes tumor metastasis in oral squamous cell carcinoma
Abstract Stress granules (SGs) are non-membranous protein–RNA aggregates that form in the cytoplasm of mammalian cells under various stress conditions. In normal cells, SGs mitigate stress-induced damage by arresting translation. SGs have also been implicated in cancer cell tumor...
- Climate & EnvironmentOpen access
Does forest management reduce wildfire severity? Evidence from 1050 plots in a South Korean Megafire
Increases in large wildfires are commonly attributed to climate change, an attribution well supported in summer-dry regions such as western North America. In the East Asian monsoon region, however, national fire trends have diverged under broadly similar warming: forest fire acti...
- BiologyOpen access
Extrachromosomal DNA: A New Therapeutic Frontier for Overcoming Cancer Drug Resistance
Extrachromosomal DNAs (ecDNAs) are acentric circular DNA molecules that frequently harbor amplified oncogenes and their regulatory elements. Although ecDNAs occur at low levels in normal cells, oncogenic ecDNAs are enriched in cancer, where they promote tumor evolution, intratumo...
- Engineering & Technology
Pressure-Gated Ionic Contact in Multilayered Nanomeshes Enables Strain-Insensitive Pressure Sensing
Abstract Soft robotic grippers require tactile interfaces that selectively detect contact pressure at the object–gripper interface without strain-induced artifacts from gripper deformation. Here, we report an ultrathin pressure-gated ionic-contact (PGIC) sensor for multidirection...
- Climate & EnvironmentOpen access
Vertical Structure of Wind-Related Coastal Cooling in a Multi-Layer Buoy Array
The cooling of surface water in coastal seas is routinely detected by surface sensors, but a surface record alone cannot show whether the water below cooled at the same time or instead became warmer, and the two patterns may arise from different physical processes. We examined te...
- Climate & Environment
Complex Upper-Mantle Anisotropy Beneath the Pacific Triangle Revealed by Shear-Wave Splitting
Abstract Understanding mantle flow beneath old oceanic plates is essential for linking present-day plate motions with long-term lithospheric evolution, yet direct constraints remain sparse due to limited offshore observations. Here, we investigate upper-mantle seismic anisotropy...
- Engineering & TechnologyOpen access
Soil Reinforcement by Woody Plant Roots: A Systematic Review and Quantitative Synthesis
Woody plant roots enhance slope stability by increasing soil shear strength, although reinforcement by roots varies with forest type, growth form, root diameter, and disturbance history. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines,...
- BiologyOpen access
Cross-regulation of iron and phosphate homeostasis by Fep1 and Pho7 in fission yeast
ABSTRACT Iron and phosphate are essential micronutrients with partially interconnected homeostatic control; however, the underlying transcriptional mechanisms that integrate these signals in the fission yeast Schizosaccharomyces pombe remain unclear. Fep1 (GATA-type repressor) is...
- Health & MedicineOpen access
Abstract Background REM sleep behaviour disorder (RBD) is the strongest prodromal marker of alpha-synucleinopathies, but whether a brief questionnaire carries prognostic information for Lewy body dementia is unclear. We tested whether criteria-based probable RBD (pRBD)—a question...
- Engineering & Technology
Waste Management for Sustainable Port Development: A Two‐Stage Data Envelopment Analysis
ABSTRACT Environmental efficiency is a pillar of overall sustainable efficiency, where the capacity to regulate carbon dioxide emissions serves as a key constraint on sustainable port development. Consequently, amid the global transition toward sustainable port operations, improv...
- BiologyOpen access
Food dehydration is a core preservation operation, but its performance cannot be judged by water removal alone.Heat and mass transfer during drying reshape cellular structure and determine changes in texture, color, flavor, nutrient stability, and storage behavior.This short revi...
- Climate & EnvironmentOpen access
This study systematically investigated oyster shell-derived CaCO 3 templating method as a novel approach to construct hierarchically porous structures on coffee waste-based carbonaceous adsorbents (CCA). The feasibility of oyster shell-derived CaCO 3 templating method was evaluat...
- Climate & Environment
The book combines the latest research results of the project IGCP 679 (Cretaceous Earth dynamics and climate in Asia). Palaeontological, stratigraphical, sedimentological, geochemical and climatical analyses are used to decipher the complex evolution of the Cretaceous ecosystem o...
- Health & Medicine
Abstract Background Intravenous (IV) iron is used in patient blood management for elderly patients with hip fractures, but its effectiveness in reducing red blood cell (RBC) transfusion remains unclear. This study evaluated the effect of preoperative IV iron on perioperative RBC...
- BiologyOpen access
The genus Alphacoronavirus (α-CoV), belonging to the family Coronaviridae , comprises positive-sense RNA viruses that infect a broad spectrum of mammalian hosts, often facilitating cross-species transmission. Bats are recognized as the ancestral reservoirs for numerous α-CoVs tha...
- Engineering & TechnologyOpen access
Lithium-ion batteries using organic liquid electrolytes face safety issues, such as flammability and explosion risks, along with low energy density. To address these limitations, we develop a composite polymer electrolyte (CPE) as a safer, higher energy density alternative. The o...
- BiologyOpen access
An L-phenylalanine coating for holey carbon cryo-EM grids improves particle distribution
Abstract Electron cryomicroscopy (cryo-EM) enables macromolecular structure determination at near-atomic resolution, yet specimen preparation remains a critical bottleneck. In particular, the number of particles available within the ice-filled holes is often limiting, and simple...
- Health & MedicineOpen access
A novel mouse calvarial defect model of osteomyelitis induced by Staphylococcus aureus (ATCC 6538)
Abstract Background Osteomyelitis is a severe bone infection that causes chronic inflammation, tissue necrosis, and vascular compromise. The infection often requires surgical debridement and prolonged high-dose antibiotic therapy. Despite numerous osteomyelitis models in differen...