Jiangnan University

Advancements in Intelligent Thawing Systems for Protein‐Based Foods: An Industry 5.0 Perspective

ABSTRACT Freezing is essential for maintaining the stability of the global supply chain for protein‐based foods such as meat and aquatic products. However, traditional thawing technologies suffer from low efficiency and severe quality deterioration. Aligned with the principles of...

Breaking the Sexual Silence of Cancer Survivors: Exploration of Sexual Distress and Health Communication Paths After Cervical Cancer Surgery Based on Qualitative Interviews

<title>Abstract</title> <bold>Objective</bold> : To better understand the challenges related to sexual function faced by patients with cervical cancer following radical hysterectomy, and to provide evidence-based insights for the development of clinical nursing strategies and hea...

Microrobots for Precision Diagnosis and Treatment in the Digestive System: A Review of Actuation Mechanisms, Structural Design, Preclinical and Translational Applications

Because lesions associated with digestive system diseases are often deeply seated, embedded within complex luminal milieus, and protected by substantial local delivery barriers, conventional diagnostic and therapeutic modalities remain constrained in their targeting capability, m...

Clinical and neurophysiology study of 17 children with epileptic negative myoclonus

BACKGROUND: Epileptic negative myoclonus (ENM) is a clinically underrecognized seizure type, and systematic data on its clinical manifestations and optimal management strategies in pediatric populations remain scarce. This case series aimed to describe the clinical manifestations...

Gut microbiota-derived indoleacrylic acid ameliorates rheumatoid arthritis by preventing necroptosis of fibroblast-like synoviocytes and regulating macrophage polarization

Rheumatoid arthritis (RA) is associated with gut metabolite dysfunction, but the contribution of tryptophan-derived metabolites to RA remains fully uncharacterized. Here, we investigated the role of the gut microbiota-derived tryptophan metabolite indoleacrylic acid (IA) in exper...

Rational Designof a Dual Mutant Degrading Enzymewith Improved Catalytic Efficiency and Acid Tolerance for Four Aflatoxins

Abstract Aflatoxins are major contaminants in raw food materials and their products. Developing enzymes that efficiently degrade multiple aflatoxins under acidic conditions has great practical value. In this study, the aflatoxin-degrading enzyme ADPPIII from Aspergillus terreus w...

ConjugatedCoordination Polymer Aerogels with UnsaturatedSingle-Atom Metal Sites for Efficient Neutral Oxygen Evolution

Abstract Designing high-performance single-atom catalysts with a precisely designed configuration is important in extensive energy-conversion technologies, which presents enormous potentials to be extensively applied. Defect-enriched conjugated coordination polymer aerogels (d-CC...

Occupational exposure to Baijiu fermentation environments alters nasal microbiota composition: a comparative analysis of Strong-flavor and Sesame-flavor production systems

ABSTRACT Traditional Chinese Baijiu fermentation environments harbor complex microbial consortia critical for product quality, yet their effects on human nasal microbiota remain poorly characterized. This cross-sectional study compared nasal microbiota profiles of Strong-flavor (...

3D simulation of flat-knitted shaped shoe uppers

Purpose Research on simulating shaped shoe uppers is still in its early stages. Most studies focus on simpler cut uppers, using texture mapping principles to directly map loop patterns onto curved surfaces. Although this method simplifies the simulation process to some extent, it...

International Students’ Academic Adjustment in South Korea: A Qualitative Case Study

Although research on international students’ academic experiences in South Korean universities has steadily grown, relatively little attention has been paid to how undergraduate international students from diverse national backgrounds experience and navigate academic adjustment i...

Synthetic Carbon-Efficient Pathway and Programmable Microenvironment for Sustainable Caffeic Acid Production

Abstract Microbial production of phenolic acids offers a sustainable alternative to plant extraction, reducing carbon loss and environmental impact. Here, we present a multi-level engineering strategy in Escherichia coli integrating carbon-efficient pathways, enzyme optimization,...

Effect of SEEKflex-guided versus conventional intubation on hemodynamic responses in elderly hypertensive patients: a randomized controlled trial

In elderly patients with preexisting cardiovascular and cerebrovascular diseases, laryngoscopy and tracheal intubation can provoke substantial hemodynamic disturbances, including hypertension and tachycardia, which may precipitate major cardiovascular or cerebrovascular events an...

Extraction-reasoning gaps in open-source LLM grading of liver pathology reports

Large language models (LLMs) may reduce the manual effort required to convert narrative pathology reports into structured research data, but it remains unclear whether their performance reflects extraction of explicit diagnostic labels or genuine histopathological reasoning. We e...

Integrated Quantum Dot Microsphere-Based MultiplexLateral Flow Immunoassay for On-Site Hazard Screening of Azole AntifungalResidues in Ecological Environment and Aquatic Products

Abstract As widely applied azole antifungal agents, climbazole (CBZ), clotrimazole (CLZ), and isavuconazole (ISKZ) can persist in environmental media and bioaccumulate in aquatic organisms, thus bringing hidden risks to the ecological environment and aquatic products. Herein, a c...

A triple-responsive smart controlled-release system for antifungal volatiles: toward sustainable agriculture via pathogen-targeted control and crop growth promotion

Fungal contamination causes substantial global food loss and waste. Among these, tomato gray mold caused by Botrytis cinerea is particularly severe, leading to a global reduction in tomato yield of 10–50%. Meanwhile, the overuse of conventional chemical fungicides has triggered a...

Temporal Multi-Omics Reveals Microbial and Metabolic Succession Following Astilbin Treatment in a Human Colonic Model

Background: Astilbin is a bioactive flavonoid with documented anti-inflammatory properties; however, its sustained interactions with the gut microbiota remain poorly understood. Fecal samples from three healthy donors were pooled and fermented with astilbin in an in vitro human c...

Electrospun Nanofibrous Architectures for Food Packaging: A Review of Pore Engineering, Permeability Control, and Sustainability

Abstract Fresh food spoils rapidly when packaging cannot balance gas exchange with moisture and microbial barriers. Conventional plastic films generally fall short of these combined demands. This review examines electrospun nanofibrous architectures (NFAs) as next-generation sust...

Enzyme discovery and catalytic mechanism insights for mitigating inhibitory effects in tobacco lignocellulose biodegradation: advances, challenges, and perspectives

Tobacco biomass constitutes a substantial yet underexploited lignocellulosic resource with considerable potential for bioconversion. However, its efficient enzymatic utilization is constrained by pronounced structural heterogeneity and the presence of diverse non-structural inhib...

Synthesis of 1,4‐Dihydroquinolines via [4 + 2] Annulation of Aminobenzylphosphonium Salts With Ethyl Benzoylacetate Derivatives

A novel synthetic strategy for the preparation of 1,4‐dihydroquinolines has been developed through [4 + 2] annulation of aminobenzylphosphonium salts (ABPS) with ethyl benzoylacetate derivatives. This protocol features mild reaction conditions, readily available starting material...

Myeloperoxidase/ASGPR Dual‐Targeting Self‐Amplifying Nanoplatform for Synergistic Anti‐Metastatic Therapy of Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) remains highly lethal due to a complex tumor microenvironment (TME) that limits therapeutic efficacy. Herein, a dual-targeted nanotherapeutic platform (SC@GRT-COF-366) based on a covalent organic framework (COF-366) is reported for synergistic HCC t...