Institution
Japan Institute for Health Security
Recent research
- Health & MedicineOpen access
Nectin-4 mediates rubella virus entry in airway and placental cells
Abstract Rubella virus (RuV) causes rubella and, when acquired during pregnancy, congenital rubella syndrome (CRS). Despite its clinical significance, the cellular entry mechanism of RuV remains poorly characterized owing to limited knowledge of host receptors, hampering pathogen...
- Health & MedicineOpen access
Catastrophic cost among multi-drug resistant tuberculosis patients in Japan: first national survey
Abstract Background Multi-drug resistant tuberculosis (MDR-TB) remains a major global health concern, often contributing substantially to financial hardship among patients and their households. World Health Organization (WHO) defines catastrophic TB cost as a total cost of TB dia...
- BiologyOpen access
Foodborne pathogens and antimicrobial resistance are major global health concerns. The integration and analysis of genomic surveillance data across human, animal, and environmental sectors remain a critical challenge in the study of foodborne bacteria. Here we investigate potenti...
- BiologyOpen access
Several exceptionally long-lived mammals show natural resistance to cancer. The longest-lived rodent, the naked mole-rat (NMR; Heterocephalus glaber ) is renowned for its remarkable resistance to carcinogenesis; however, it is unclear whether other long-lived African mole-rat spe...
- Health & MedicineOpen access
While most comparative studies on the severity of COVID-19 and influenza have focused on hospitalization and mortality, the disease burden in populations not requiring hospitalization remains poorly characterized. We aimed to compare the acute disease burden of influenza versus C...