Jagiellonian University

Optimization of platelet concentrate inventory management using a simple standardized decision‐support model: A retrospective study from a Regional Blood Center

Abstract Background and Objectives Platelet concentrates (PCs) are difficult to manage because of their short shelf‐life and variable clinical demand. The aim of this study was to evaluate the impact of a modified platelet inventory management strategy at a Regional Blood Donatio...

Large-scale benchmarking of prokaryotic annotation tools across thousands of species

Abstract Background Genome annotation is an important step in deriving functional meaning from prokaryotic sequencing data, yet systematic evaluations guiding tool selection are lacking. We present the first large-scale investigation of four prominent open-source annotation tools...

Plurality in transformative change: Three co‐created pathways toward nature‐positive Europe(s)

1.The accelerating decline of biodiversity necessitates transformative change to protect nature and society, requiring innovative actions and governance strategies. This paper focuses on developing diverse transformative pathways for biodiversity in Europe and advancing methodolo...

Perspectives on influential factors for the adoption of circular economy practices

Abstract This study aims at contributing to improve understandings of influences that factors may exert on processes of adoption of circular economy (CE) practices by diverse types of organisations. Its propositions offer perspectives structured from categories identified as suit...

Adrenal incidentalomas: 1 mg dexamethasone test result in the context of cardiometabolic risk

Mild autonomous cortisol secretion (MACS) is the most common hormonal abnormality in adrenal incidentalomas. The 1 mg dexamethasone suppression test (DST) with a cutoff of 1.8 µg/dL is used to exclude hypercortisolism, yet some “non-functioning” tumors may secrete cortisol at con...

Plastic incompatibility stresses arising from slip and twinning in extruded AZ31 magnesium alloy: In-situ synchrotron diffraction analysis using self-consistent modeling

This study presents a comprehensive investigation into the bulk internal stress evolution within an extruded AZ31 magnesium alloy subjected to both in-situ uniaxial tensile and compressive loading. Using energy-dispersive synchrotron X-ray diffraction (ED XRD), first-order macros...

Frameworks to identify research gaps, frame research needs, and derive research priorities from evidence syntheses:a scoping review

Objectives To identify and describe frameworks for systematically identifying research gaps from evidence syntheses, framing research needs, and establishing priorities, with emphasis on their use of GRADE (Grading of Recommendations Assessment, Development and Evaluation) certai...

Clinical characteristics associated with failure to achieve a prespecified guideline-directed medical therapy target at discharge in patients with HFrEF undergoing scheduled hospitalization: a secondary analysis of the HEROES study

Abstract Guideline-directed medical therapy (GDMT) is crucial for the pharmacological management of heart failure (HF) with reduced ejection fraction (HFrEF). The aim of the study was to identify clinical characteristics associated with failure to achieve the prespecified stringe...

LDL Cholesterol Lowering With Evolocumab Before Percutaneous Coronary Intervention for Acute Myocardial Infarction

Importance: Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibition is recommended as second- or third-line lipid-lowering therapy after myocardial infarction (MI), resulting in prolonged periods of inadequate low-density lipoprotein cholesterol (LDL-C) control. Whether...

Investigating graduates’ perception of overall goal attainment of a resilience-focused medical program offered in the United Arab Emirates: a quantitative cross-sectional study, 2025

It is vital to develop transversal skills that collectively reinforce individual learners’ resilience. Although resilience-focused initiatives are widely adopted in health and care professions’ education, these initiatives seem to take the form of discrete interventions, as oppos...

Beyond B cells: T and Innate Immune Mechanisms of Autoimmunity in Common Variable Immunodeficiency

Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency, affecting approximately 1 in 25 000–50 000 individuals. Although classically characterized by hypogammaglobulinemia and recurrent bacterial infections, over 50% of patients develop...

Evidence for long-distance contacts at the turn of eras: A leontomorphic fibula from Kuyavia (Poland). A contribution to the study on the European family of lion-bow fibulae

Abstract Located in the North European Plain and the heart of the Polish lands, the historic region of Kuyavia has long been an area where cultural communication and trade routes criss-crossed. This geographical characteristic had transformative effects on the region’s inhabitant...

Post-gaming return to reality: a key factor in predicting the positive and negative outcomes of escapism

Background and aimsEscapism is a key gaming motive associated with both psychological relief and Gaming Disorder. Yet, existing models often neglect the dynamic role of goal attainment in shaping gaming outcomes. Drawing on Goal Systems Theory, we introduce the construct of Post-...

Cardiovascular Sequelae After SARS-CoV-2 in Children: From Myocardial Injury to Dysautonomia and Implications for Phenotype-Guided Follow-Up

To summarise current paediatric evidence on long-term cardiovascular sequelae after SARS-CoV-2 infection, with particular emphasis on the place of multisystem inflammatory syndrome in children (MIS-C), persistent subclinical myocardial abnormalities and autonomic dysfunction. A c...

Unique geochemical conditions and microbial composition of pockmark sediments in a brackish-water eutrophic continental shelf sea

Abstract In marine pockmarks, interactions between outflowing gas, infiltrating freshwater, and increased input of organic matter (OM) affect the supply and utilization of particular electron acceptors required primarily for OM mineralization. Consequently, geochemical processes...

Entropy maximization and weak Gibbsianity of quasi-free fermionic states

Abstract In their 1972 study of approach to equilibrium, Lanford and Robinson showed that gauge-invariant quasi-free states of lattice fermions maximize entropy among all translation-invariant states with a fixed two-point function and suggested that the maximizer is unique. In s...

Enabling stable preservation of ML algorithms in high-energy physics with petrifyML

Machine learning (ML) in high-energy physics (HEP) has moved in the LHC era from an internal detail of experiment software, to an unavoidable public component of many physics data analyses. Scientific reproducibility thus requires that it be possible to accurately and stably pres...

Saturable absorption in NV-doped diamond studied by femtosecond Z-scan

Nonlinear optical absorption in commercially available diamond crystals containing nitrogen-vacancy (NV) centers is investigated using femtosecond open-aperture Z-scan measurements at a wavelength of 1032 nm. Experiments were performed on a high-purity electronic-grade diamond an...

Methodological Approaches to Bioavailability of Oral Creatine in Randomized Controlled Trials: A Meta-Research Study

Background: Creatine is one of the most widely used dietary supplements for enhancing physical performance and is increasingly investigated for a range of health-related applications. Although creatine monohydrate is the most commonly used formulation, concerns have been raised r...

Current Trends and Advances in Research on Rare Earth Elements (REEs) in Groundwater: A 2010–2025 Bibliometric Analysis

Abstract Rare earth elements (REEs) are becoming increasingly important in the global economy and environmental research, especially in studies of water circulation and water chemistry. The paper presents the results of a bibliometric analysis of studies on the presence of REEs i...