Instituto Nacional de Saúde

Assessing Behavioral and Environmental Facets of Obesity Unobtrusively Utilizing Digital Tools: Introducing the BETTER4U Indicators

ABSTRACT Understanding obesity involves evaluating numerous contributing factors. Collecting the necessary data for this can impose a significant burden on both research participants during clinical studies and real‐life deployments of digital tools aiding obesity management. The...

Measurement of Tuberculosis treatment adherence: A methodological scoping review of observational studies

Despite extensive conceptual development, the definition and measurement of Tuberculosis (TB) treatment adherence remain inconsistent. This ambiguity obscures what is being assessed and compared across studies. This scoping review examined how adherence is labelled, defined, and...

HIV-1 Drug Resistance in Mother–Infant Pairs in Southern Mozambique

This prospective nested cohort (EARTH) study evaluated drug resistance mutations and outcomes among 79 (31 with genetic results) early-treated Mozambican children living with HIV, followed for 50 months. Mortality reached 20.3%. Drug resistance mutations were detected in 58.1% of...

Bridging the gaps: how knowledge and access to care influence timely cholera treatment and reduce deaths in Nampula Province, Mozambique

Despite global efforts to improve cholera case management and reduce case fatality, persistent gaps remain in understanding local health-seeking behaviors and community knowledge. This study aimed to investigate these factors in Nampula province, Mozambique, which experiences fre...

Enteric pathogens in soil adjacent to public waste bins in Maputo, Mozambique offers potential for environmental surveillance

Abstract Wastewater surveillance has been widely adopted since the COVID-19 pandemic, but non-sewered or onsite sanitation is a common form of sanitation in cities of low- and middle-income countries. Environmental surveillance in these settings requires expanding analyses beyond...

The value of mortality data to advance learning and decision-making dynamics in Mozambique’s health system

Abstract Introduction There is a lack of evidence on whether and how health systems stakeholders in Mozambique learn from routine health data. Despite the recurring claim by the stakeholders themselves that data in general should be the centre of informed public health policy, it...

Diagnostic performance of a centrifugation-free stool processing kit in conjunction with Xpert®MTB/RIF Ultra for paediatric tuberculosis: a multicentre prospective study in five low and middle-income countries

Diagnosing paediatric tuberculosis (TB) remains challenging. Currently available diagnostic tests have limited accuracy, and most sampling methods are invasive. In 2021, the World Health Organisation (WHO) endorsed the use of molecular WHO-recommended rapid diagnostic tests (mWRD...