Institute for Medical Informatics and Biostatistics

Biventricular vs conduction system pacing after atrioventricular node ablation for heart failure with atrial fibrillation: the CONDUCT-AF trial.

BACKGROUND AND AIMS: Randomized evidence comparing conduction system pacing (CSP) and biventricular pacing (BVP) following atrioventricular node ablation in patients with refractory atrial fibrillation (AF) and heart failure (HF) remains limited. This study evaluated whether CSP...

Baseline Liver Metabolic Health in Newly Diagnosed People Living with HIV Compared with HIV-Negative Controls: Cross-Sectional Findings from the Prospective MASHIV-TR Cohort

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an important comorbidity in people living with HIV (PLWH), yet most data derive from individuals receiving antiretroviral therapy (ART). In the baseline cross-sectional analysis of the prospective multicentre MAS...

Evaluating menopausal symptom burden and treatment engagement in a predominantly Hispanic population on the United States‐Mexico border

Objective: To evaluate menopausal symptom burden, health care engagement, and treatment disparities among postmenopausal women at the United States‐Mexico border. Methods: A cross-sectional bilingual survey was administered to postmenopausal women receiving care from 2021 to 2024...

Longitudinal health-related quality of life after electrochemotherapy in elderly patients with cutaneous melanoma

The incidence of cutaneous melanoma (CM) is increasing among elderly patients, who often present with advanced disease, including cutaneous metastases. Electrochemotherapy (ECT) is a local ablative treatment that enhances chemotherapy uptake via electric pulses. Management in pat...

Integrated serum and synovial biomarker profiling reveals inflammatory and cartilage remodeling signatures in age-restricted knee osteoarthritis

Knee osteoarthritis (OA) is a complex disease characterized by inflammation, cartilage degeneration, and tissue remodeling. Although many biomarkers have been investigated, the combined biological significance of systemic and local biomarkers is not fully understood. This study a...