Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Parabens and estrogen-mediated cancers: unraveling coincidence, co-occurrence, and causality

Abstract Paraben esters are endocrine disruptors linked to breast cancer, yet their role in other estrogen-mediated cancers remains limited. Preclinical evidence suggests that parabens accumulate in tissues and may promote carcinogenesis, while clinical data indicate widespread e...

Co-evolution of plants, livestock and farming practices during dairy farm transformation to agroecology: an in-depth case study in France

Agriculture contributes to and is impacted by global changes. Agroecology is recommended as a framework for transforming farming systems to address these challenges. However, research has not extensively documented transformations to agroecology, which could limit adoption by far...

Urbanisation and habitat loss favour thermophilic and monogynous ant species

Environmental changes such as urbanisation and related habitat loss and fragmentation profoundly impact ecological communities by altering habitats, resources, and microclimates. Yet, the impacts of the resulting environmental conditions on metacommunity dynamics, ranging from sp...

How to measure the perimeter from digital images

Image analysis aims at extracting quantitative information from digital images. As for any measurement method, the measures obtained from image analysis present some measurement errors that should be better considered during interpretation of results. This work investigates the q...

Simulation-based inference of epidemiological and phylodynamic models via neural posterior estimation

Mathematical models play a central role in understanding and forecasting infectious disease dynamics, but parameter inference is often difficult when likelihoods are intractable. Simulation-based inference (SBI) circumvents this limitation by relying on model simulations. Traditi...

Ecosystem-scale biogenic volatile organic compound fluxes over rapeseed by eddy-covariance

Abstract. Biogenic volatile organic compounds (BVOCs) are key precursors of ozone and secondary organic aerosols, yet their emissions from croplands remain poorly characterized. Here, we report what is, to our knowledge, the first ecosystem-scale quantification of BVOC fluxes ove...

A nationally representative One Health multi-pathogen serosurvey in Cambodia: study protocol for the RACSMEI mixed-methods study

Abstract Background Cambodia faces a high and complex burden of zoonotic, vector-borne, vaccine-preventable and environmentally transmitted infections, driven by intensive human–animal–environment interactions. However, nationally representative data integrating human, animal and...

Grassland destruction causes shifts in plant traits that persist during recovery

Old-growth grasslands assemble over millennia and support high biodiversity and many ecosystem services, but continue to undergo widespread destruction for production of crops, timber, and minerals. How biodiversity recovers after grassland destruction and the functional conseque...

Polyphenol-Rich Opuntia ficus-indica Cladodes: An Integrated Metabolomic, In Vivo and In Silico Study Supporting Their Hypolipidemic and Hepatoprotective Effects

Background: Hyperlipidemia is a major risk factor for cardiometabolic disorders, including non-alcoholic fatty liver disease (NAFLD), and is closely associated with oxidative stress. Opuntia ficus-indica (OFI) cladodes are recognized as a rich source of bioactive phytochemicals;...

Prediagnostic circulating 25-hydroxyvitamin D and prostate cancer-specific survival: a collaborative pooled analysis of 13 prospective studies

Abstract Background Previous research suggests higher risk of prostate cancer diagnosis in men with high vitamin D serology, but there are limited data related to prostate cancer survival. In this study, we examine the associations between prediagnostic circulating levels of 25-h...

Uncovering Newcastle disease virus dynamics in Northern Nigeria: insights from an epidemiological survey in unvaccinated village poultry

Abstract Background Newcastle disease virus (NDV) remains a major constraint to village and backyard poultry production in Nigeria, where limited vaccination and low biosecurity may facilitate sustained virus circulation. This study investigated the serological and molecular epid...

Pectin–Protein Complexes: A Design‐Oriented Platform for Tailoring Food Texture Modification

ABSTRACT Pectin–protein complexes have emerged as promising functional ingredients in texture‐modified foods (TMF) due to their multifunctional roles in gelation, emulsification, and water retention. These properties enable the design of customized textures for applications such...

Infrastructuring short food supply chains: how intermediaries bind rules, norms and values

Food supply chains are crucial for food security and socio-economic development, yet their length concentrates value away from producers and consumers disproportionate resources. As the COVID-19 pandemic and the wars in Ukraine and Iran exposed, overreliance on long chains produc...

Impact of extreme rainfall on triggering conditions and susceptibility for shallow landslides: a case study in the Alpes-Maritimes region (France)

Abstract. Prediction of shallow landslides at the regional scale generally relies on statistical analyses of landslide inventories. Rainfall-duration thresholds and susceptibility maps are among the most common approaches to anticipate future landslide occurrences. However, the o...

Identification of living (Rose Bengal)-stained benthic foraminifera using automated image recognition

Abstract. Living and fossil benthic foraminifera are widely used as bioindicators of ecosystem quality, but their analysis is time-consuming. With the help of artificial intelligence, models for the automatic identification of fossil planktonic foraminifera and, more recently, be...

Potential glacier contributions to the 2024 La Bérarde flood

Abstract. On 20–21 June 2024, an unprecedented flood of the Etançons river caused important damage to the village of La Bérarde (Écrins, France). An analysis of the event showed that the flood was caused by the combination of an intense rain-on-snow event at high altitude and the...

Breast cancer metabolism and responsiveness to dichloroacetate: relationships with 15N and 13C natural abundance

Abstract Background Metabolic reprogramming is a hallmark of breast cancer (BrCa), with alterations in glycolysis, glutamine metabolism, and the urea cycle contributing to tumour progression. Dichloroacetate (DCA), a pyruvate dehydrogenase kinase (PDK) inhibitor, shifts metabolis...

Toward Climate-Responsive Ocean–Terrestrial Biorefineries: Integrating Algae and Agricultural Residues for Circular Bioeconomies

Abstract This paper evaluates climate-responsive biorefineries that integrate pelagic Sargassum with agricultural residues to advance circular bioeconomies. Building on scientific priorities emphasized at the 2025 One Ocean Science Congress and emerging policy directions from the...

Iron Isotopes Reveal Fe Export Driven by Change of Tropical Weathering Regime

Abstract Unraveling paleoenvironmental signals recorded in laterites is crucial for quantifying weathering‐driven elemental fluxes at the Earth's surface. New stable iron isotope data (δ 56 Fe), combined with (U‐Th)/He ages in Fe‐oxides from a ferruginous duricrust from French Gu...

A Dynamic Mechanism for Prevalence of Triangles in Competitive Networks

Abstract Triangles are abundant in real-world networks but rare in standard null models for sparse graphs. Existing explanations typically rely on explicit triadic closure mechanisms or geometry-based connection rules. We propose an alternative hypothesis: the frequent appearance...