Huazhong Agricultural University

Effect of Nano- and Microparticulate Fermented Fish Protein Hydrolysate Diets on Growth, Digestive Function, Intestinal Development, and Gene Expression in Common Carp (Cyprinus carpio) Larvae

The early larval stage is a major bottleneck in freshwater aquaculture because conventional live feeds are not always available for optimum nutrient availability and digestibility to satisfy the nutritional requirements of developing larvae. This study evaluated the effects of mi...

Underground Signals: The Ecological Power of Root Volatiles

Root volatiles mediate diverse belowground interactions among plants, microbes, and invertebrates, but biological and environmental conditions strongly influence their production, movement, perception, and ecological effects. This review synthesizes current knowledge through an i...

Melanomacrophages exhibit FDC-like features: aquatic reovirus induces melanomacrophage death to suppress antibody responses

Genotype II grass carp reovirus (GCRV-II)-caused grass carp hemorrhagic disease severely restricts aquaculture, yet its adaptive immune evasion mechanism remains unclear. In mammals, follicular dendritic cells (FDCs) act as the core antigen-presenting cells that drive germinal ce...

Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral blood

Regular exercise is well established to protect against metabolic disorders and bolster immunity, but the underlying molecular and cellular mechanisms remain incompletely understood. We integrated plasma metabolomics and lipidomics with single-cell transcriptomic and chromatin ac...

Integrative Multi‐Omics Analysis Identifies Candidate MicroRNA Regulatory Networks Associated With High‐Altitude Adaptation in Tibetan Pigs

MicroRNAs (miRNAs) are key posttranscriptional regulators of gene expression and play important roles in physiological responses to hypoxia, particularly in the cardiovascular system. However, the regulatory roles of miRNAs in cardiopulmonary tissues during high-altitude adaptati...

Large language models for literature screening in conceptually complex and interdisciplinary reviews

Purpose This study examines the capabilities and limitations of large language models (LLMs) for literature screening in systematic reviews involving conceptually diffuse and interdisciplinary topics. Design/methodology/approach Two screening datasets were constructed. Four LLMs,...

GhGFS9 promotes proanthocyanidin and anthocyanin accumulation in brown cotton fiber via vesicle trafficking and biosynthetic regulation

Naturally colored cotton (NCC) serves as a green alternative to conventional dyeing processes in the textile industry; however, its limited color spectrum restricts broader application. Proanthocyanidins (PAs) and their derivatives are key pigments in brown cotton fiber, but the...

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

Abstract Postoperative recurrence remains a critical challenge in cancer management, necessitating innovative strategies to reshape the tumor microenvironment (TME) and enhance immune surveillance. This review highlights nanomedicine‐driven breakthroughs in postoperative immunoth...

Organosilicon-Mediated Cadmium Uptake, Transport, and Detoxification in Rice: Comparison Between Low-Cd and Conventional Rice Varieties

Cadmium (Cd) contamination in rice threatens rice food safety. Organosilicon shows substantial potential to reduce the uptake and accumulation of Cd in crops. However, the current understanding of the mechanisms by which organosilicon reduces Cd toxicity in rice remains fragmente...

Morphological and phylogenetic analyses reveal two new species of Chaetosphaeriaceae from Jiangxi Province, China

Chaetosphaeriaceae is a group of micro-ascomycetes widely distributed in diverse ecosystems worldwide. Group members are commonly found on decaying wood, leaf litter and in moist soil. However, their diversity in soil habitats, especially in understudied bamboo forest ecosystems,...

WLG coordinates multi-stress tolerance in rice by regulating DST-dependent H2O2 homeostasis and stomatal aperture

Abiotic stresses reduce rice growth and yield, yet the mechanisms underlying multiple stress tolerance are unknown. Here, we show that the E3 ubiquitin ligase WIDTH OF LEAF AND GRAIN (WLG) enhances drought, salt, and heat tolerance by ubiquitinating and degrading DROUGHT AND SALT...

Comparative Analysis of Intermuscular Bones in Five Characiform Species and Their Early Development in Tambaqui (Colossoma macropomum)

Intermuscular bones (IBs) are spicule-like, ossified structures located in the myosepta of muscles on either side of the vertebrae that are unique to several orders of teleost fishes, including Order Characiformes, for which research on the characteristics of IBs is limited. We i...

Multi‐omics characterization of flavor profile differences in the Longissimus thoracis between Angus and Hereford cattle

Abstract BACKGROUND Angus and Hereford cattle are premier breeds widely used in genetic improvement and crossbreeding programs to enhance meat quality, yet the flavor differences between them remain poorly understood. RESULTS In this study, we performed an integrated analysis usi...

When plateware shape matters: The congruence effects between food pungency and plateware shape on food preference

Although considerable attention has been paid to enhancing the visual appeal of food, less is known about how plateware design should align with the sensory characteristics of food. Drawing on shape-taste correspondence research and processing fluency theory, this research examin...

Hos2-mediated KatG1 decrotonylation orchestrates ROS scavenging in rice blast infection

In plant–pathogen interaction, plants trigger reactive oxygen species (ROS) bursts to defend against pathogen invasion, while pathogens evolved antioxidant systems to scavenge ROS for infection. Our study reveals a regulatory mechanism of ROS adaptation and scavenging in the rice...

Sorghum-rice-barley diet reshapes maternal gut microbiota and metabolites in sows to improve lactation efficiency and suckling piglet growth

Maternal nutrition during late gestation and lactation profoundly influences the development of porcine offspring. This study investigated the effects of replacing a conventional corn-soybean meal diet (CON) with a sorghum-rice-barley (SRB) diet on sow lactation performance, mate...

Impact of Thermal Processing and Storage on the Quality and Chirality of Linalool in Blueberry Juice

Blueberry juice is valued for its distinctive flavor and health-promoting bioactive compounds, but thermal processing and subsequent storage can alter its quality and aroma. While previous studies have focused on total volatile profiles, the behavior of chiral aroma compounds—par...

A Novel Mouse Model for Venous High-Load Remodeling Induced by Unilateral Jugular Vein Transection

Chronic venous disease (CVD) is a prevalent peripheral vascular disorder characterized by vascular remodeling driven by hemodynamic overload, yet available animal models are limited by high surgical difficulty and unstable induction efficiency. Here, we developed a novel mouse ve...

Immunogenicity and protective efficacy evaluation of an inactivated Lawsonia intracellularis vaccine candidate developed on the basis of a Chinese isolate in pigs

Abstract Porcine proliferative enteropathy (PPE), caused by the obligate intracellular bacterium Lawsonia intracellularis (LI), is an important enteric disease of pigs that impairs intestinal function and growth performance. Vaccination is the most effective measure for the preve...

Ovalbumin peptides exert bidirectional immunomodulatory activity in vivo via regulating cytokines and antioxidant capacity

The ideal immunomodulatory peptides should possess both immune-enhancing and anti-inflammatory properties. This study investigated the bidirectional immunomodulatory activity of ovalbumin peptides (OVAP) using immunocompromised and inflammatory mice models integrated with network...