Hokkaido University

A bibliometric-systematic review of CGM’s application in lifestyle and behavioral research among healthy individuals: proposing a novel typology

Abstract Background Blood glucose management has progressed from diabetes treatment to tracking trends in healthy populations since the introduction of continuous glucose monitoring (CGM) in 1999. Previously, this population was difficult to study using traditional self-monitorin...

Serum soluble Fas levels and incidence of biliary tract cancer in a nested case-control study

Abstract Background: Soluble Fas (sFas) plays multiple roles in tumorigenesis and cancer dissemination by avoiding apoptosis via connection to Fas ligand. We assessed associations of serum sFas levels with the incidence of extrahepatic biliary tract cancer (eBTC) in a prospective...

A unified framework for estimating fingertip forces and muscle activations in human grasping with anatomical modeling and soft-finger contact

Abstract We developed a method to estimate fingertip forces, torques, and muscle activations during object grasping with a digital hand model. Grasping an object requires several equilibrium conditions: force and moment balance on the object, consistency between fingertip forces...

Gaming Disorder Risk, Gaming Time, and Student Life Satisfaction Among Japanese Students: A Pilot Cross-Sectional Study Using the GADIS-A

Background: Problematic gaming has been linked to reduced well-being, but associations between student life satisfaction and gaming-related risk among students remain relatively untested. This pilot cross-sectional study applied the Japanese version of the Gaming Disorder Scale f...

Whole-body depth camera gait analysis with artificial intelligence for recognizing anterior cruciate ligament deficient gait compared with healthcare professionals

Anterior cruciate ligament (ACL) injury can be missed during the initial evaluation because compensatory strategies may conceal subtle gait abnormalities. We evaluated the accuracy with which healthcare professionals recognize ACL deficient gait from brief visual observation and...

Day-to-day atmospheric circulation modulated the impact of marine heatwaves on heatstroke risk in Hokkaido in August 2023

Abstract Extreme high temperature and humidity threaten high-latitude regions that are less adapted to such conditions. While marine heatwaves (MHWs) can contribute to hot and humid conditions over land, the modulation of these impacts by the day-to-day atmospheric circulation re...

Remarks on “Pair-MERGE as Set-MERGE”: Internal Pair-MERGE of heads reconsidered

Abstract This article points out that any reformulation of Pair-MERGE as Set-MERGE based on Zermelo-Fraenkel Set-Theory with the Axiom of Choices (ZFC) (Omune 2018; Nakashima 2022) faces both conceptual and empirical problems. First, we show that it inevitably violates the Princi...

Spiderweb‐Inspired Conformable Stretchable Electronic Skin for Tactile Force and Softness Perception

ABSTRACT Electronic skin (e‐skin) that can conformably cover deformable surfaces is essential for robotic perception and wearable human–machine interfaces. However, simultaneously achieving high spatial resolution, multimodal sensing, and mechanical stretchability remains challen...

Macrophage-driven pathological ossification of the posterior longitudinal ligament: mechanistic insights and therapeutic opportunities

Abstract Ossification of the posterior longitudinal ligament (OPLL) is a chronic degenerative spinal condition in which bone gradually forms within the ligament, compressing the spinal cord and causing progressive neurological decline. While genetic predisposition and metabolic d...

Stringy Constraints on Modular Flavor Models

Abstract We investigate stringy constraints on moduli spaces in modular flavor models by analyzing moduli-dependent threshold corrections in heterotic string vacua. While moduli play a crucial role in determining the flavor structure of fermions predicted by modular flavor models...

Fatty acid signatures distinguish autotrophy, partial mycoheterotrophy, and full mycoheterotrophy in angiosperms

Abstract Detecting partial mycoheterotrophy in green plants remains challenging, particularly in associations with arbuscular mycorrhizal (AM) or rhizoctonia fungi, because natural-abundance stable isotope patterns often provide limited diagnostic resolution in these systems. We...

Impact of Non-curative Endoscopic Submucosal Dissection on Minimally Invasive Distal Gastrectomy and on Robotic Versus Laparoscopic Approaches in pT1 Gastric Cancer

Background/Aim: The impact of prior non-curative endoscopic submucosal dissection (ESD) on the safety and oncological adequacy of minimally invasive distal gastrectomy (MIDG) for pT1 gastric cancer is uncertain. Comparative evidence for laparoscopic versus robotic distal gastrect...

Association Between Oral Frailty and Body Mass Index in Late-Stage Older Adults Stratified by Sarcopenia Status

Objectives: Oral frailty is associated with sarcopenia and underweight; however, its relationship with sarcopenic obesity remains unclear. This cross-sectional study investigated the associations between oral frailty and body mass index (BMI) categories (underweight/obesity), str...

Response to “Sample Representativeness and Test–Retest Reliability in the Japanese Everyday Ageism Scale: A Methodological Reconsideration”

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

Cellulose-fueled extracellular electron transfer in termite gut microbes

ABSTRACT Termites decompose billions of tons of lignocellulosic material annually through the cellulolytic metabolism of their gut microbiota. However, the mechanisms by which cellulose degradation drives anaerobic metabolism of the gut microbiome remain poorly understood. Here,...

Higher postpartum α-defensin secretion is associated with diet during pregnancy and lower intensity of negative maternal mood

Abstract Perinatal anxiety and depression are serious concerns for many mothers. However, current early-phase community-based care is not always sufficient to prevent their aggravation, necessitating self-care approaches through daily habits that lower social and psychological im...

Early administration of calcineurin inhibitors limits tolerogenic effect of PTCy in allogeneic hematopoietic transplant

We recently demonstrated early administration of calcineurin inhibitors (CNIs) after murine allogeneic hematopoietic cell transplantation (allo-HCT) inhibits terminal exhaustion of donor T cells and hampers tolerance induction. However, the role of CNIs in regulating T-cell exhau...

Luminescence Control in Polyesters via Chain‐Motion‐Regulated Through‐Space Electronic Interaction

ABSTRACT Stimuli‐responsive luminescent polymers translate changes in molecular mobility or transformation into optical outputs; however, most systems rely on synthetically elaborate architectures that hinder broad implementation. Here, a very simple polyester, synthesized via ri...

Impacts of Different Monin–Obukhov Parameterizations on Seasonal Turbulent Heat Flux Estimates Over Snow Surfaces

Abstract Modeling of turbulent heat fluxes over snow surfaces almost exclusively depends on the Monin–Obukhov similarity theory. Within this framework, this study evaluates the impact of different parameterizations, including roughness lengths and stability correction functions,...

Time-Temperature-Transformation Diagrams to Navigate the Nucleation and Quenchability of Metastable α-Li₃PS4

α-Li₃PS₄ is a promising solid-state electrolyte with the highest ionic conductivity among its polymorphs. However, its formation presents a thermodynamic paradox: the α-phase is the equilibrium phase at high temperature and transforms to the stable γ-Li3PS4 polymorph when cooled...