Hamad Medical Corporation

Factors influencing medication management during emergency department-to-home transitions: a qualitative study using the theoretical domains framework

Abstract Introduction The transition from Emergency department (ED) to home represents a high-risk period in the continuum of patient care, increasing the risk of medication errors, adverse drug events, and poor adherence. This study explored the perspectives of key stakeholder g...

Surgical Success in Obstructive Sleep Apnea Patients Using Preoperative Drug‐Induced Sleep Endoscopy and Awake Endoscopy Considering Disease Severity

ABSTRACT Background Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent episodes of airway obstruction during sleep, leading to fragmented sleep and oxygen desaturation. Identifying the precise site and pattern of obstruction is essential for surgical...

Fatty liver and adipokines: converging pathways linking insulin resistance to early atherosclerosis in obese children and adolescents

Abstract Introduction Childhood obesity drives nonalcoholic fatty liver disease (NAFLD) and adipokine dysregulation, converging on insulin resistance (IR) to promote subclinical vascular injury measurable as increased carotid intima–media thickness (cIMT). Pediatric-specific mech...

The Upward Alliance: A Theory of Bilateral Upgaze Organization

Author: Dr. Ghassan Ahmed Mubasher Mohamedsalih Neuro-OphthalmologistHamad Medical Corporation, QatarEmail: Gmohamedsalih@hamad.qaORCID: https://orcid.org/0009-0000-7926-3150 Description Upgaze and downgaze exhibit a fundamental anatomical asymmetry within the vertical oculomotor...

Enhanced Functional Independence Score for Haemophilia (E‐FISH) for Early Detection of Musculoskeletal Changes

BACKGROUND: The functional independence score in haemophilia (FISH) is a widely used performance-based assessment tool designed to evaluate musculoskeletal function in children with haemophilia (CWH). Nevertheless, FISH exhibits a ceiling effect in children who are undergoing ear...

Infectious Complications in Adults Receiving Extracorporeal Membrane Oxygenation: A Systematic Review and Meta-Analysis of Nosocomial and Bloodstream Infection, Prevalence, Risk Factors, and Clinical Outcomes

Background/Objectives: Reported infection rates during extracorporeal membrane oxygenation (ECMO) vary widely, partly because case definitions are applied inconsistently. We synthesized the prevalence and prognostic association of nosocomial and bloodstream infection (BSI) acquir...

HPV vaccination and cervical cancer deaths: from incidence reduction to mortality prevention

Abstract Persistent infection with carcinogenic human papillomavirus (HPV) types causes the great majority of cervical cancers. For more than a decade, randomized trials, surveillance studies, and national registry analyses have demonstrated reductions in vaccine-type HPV infecti...

Oral tebipenem pivoxil for complicated urinary tract infections: evidence, potential role in IV-to-oral transition, and antimicrobial stewardship

Abstract Purpose Complicated urinary tract infections (cUTIs), including pyelonephritis, are increasingly challenging when resistant Enterobacterales eliminate conventional oral treatment options. Tebipenem pivoxil (UTEBZI), approved by the US Food and Drug Administration in June...

Zero-touch technique: a new paradigm in penile prosthesis surgery enabled by a sterile genital barrier system

Abstract Penile prosthesis (PP) implantation remains the most definitive treatment for medication-refractory erectile dysfunction (ED). Despite reductions in infection rates achieved through improved PP coatings, antimicrobial protocols, and refined surgical techniques, PP infect...

Gene Expression Biomarkers for Breast Ductal Carcinoma in Situ Recurrence Prediction

ABSTRACT Breast ductal carcinoma in situ (DCIS) is often overtreated due to a lack of robust prognostic and predictive tools. This study aimed to evaluate gene expression in a well‐characterised DCIS cohort to determine their clinical utility as biomarkers for ipsilateral recurre...

A Rare Entity in Context: Breast Implant-Associated Anaplastic Large Cell Lymphoma Compared With Common Lymphoma Subtypes

Objective: edition World Health Organization Classification of haematolymphoid tumors. Its clinicopathologic profile, treatment patterns, and outcomes, relative to those of other primary breast lymphomas, have not been characterized in large population-based comparative studies....

Kidney cancer in Eastern Mediterranean Region and Qatar: epidemiological burden patterns and etiologic risk pathways

Abstract Kidney cancer contributes substantially to the global cancer burden, with significant geographic and sex differences. Countries in the Eastern Mediterranean Region (EMR) show rising incidence and mortality alongside gaps in registry coverage and high prevalence of metabo...

Effect of a tele-orthodontics platform on knowledge, attitudes, and practices among orthodontic professionals in Yemen: a single-arm pretest–posttest intervention study

Abstract Objectives To evaluate the effect of a tele-orthodontics platform on orthodontists’ and orthodontic residents’ knowledge, attitudes, and practices (KAP) in Yemen, as well as to assess the platform’s acknowledged benefits, obstacles, and consultants’ responsiveness. Metho...

Ethical Governance of Open Data Across Biomedical Research, Healthcare, and Public Health: Privacy, Equity, Trust, and Controlled Access

Open data has become central to biomedical research and public health, but health information is uniquely sensitive and difficult to share responsibly. In this narrative review, open data is considered as a spectrum of health-data sharing arrangements, ranging from public aggrega...

Acute fibrinous and organising pneumonia (AFOP): a case series highlighting diverse aetiologies and clinical outcomes in three patients

Background Acute fibrinous and organising pneumonia (AFOP) is a rare histopathological pattern of acute lung injury characterised by intra-alveolar fibrin deposition and organising pneumonia. It has diverse aetiologies and highly variable clinical outcomes.Case presentations We r...

Efficacy and safety of chimeric antigen receptor T-cell therapy in primary central nervous system lymphoma: a systematic review and meta-analysis

Background Evidence for chimeric antigen receptor T-cell (CAR-T) therapy in primary central nervous system lymphoma (PCNSL) remains limited and heterogeneous, with prior syntheses often combining primary and secondary CNS lymphoma.Methods We systematically searched PubMed, Scopus...

Carvedilol for prevention of cardiotoxicity in patients receiving anthracycline-based chemotherapy: a systematic review and meta-analysis

Chemotherapy-induced cardiotoxicity, particularly from anthracyclines, limits treatment in oncology patients. Carvedilol, a third-generation β-blocker with antioxidant properties, may offer cardio protection. However, comparative evidence for carvedilol and its metabolites remain...

Effectiveness of Flipped Classroom and Traditional Didactic Classroom in Paediatric Dentistry Education—A Systematic Review With Meta‐Analysis of Randomised Controlled Trials

ABSTRACT Introduction The flipped classroom (FC) is a contemporary teaching strategy that has gained considerable attention in recent years. This model relies on technology‐based resources, including videos and handouts, to deliver illustrative content and core subject material t...

Atherogenic lipid profile changes and their cardiovascular consequences across degrees of obesity in children and adolescents: a structured narrative review

Key messageChildren and adolescents with obesity commonly develop atherogenic dyslipidemia characterized by elevated triglyceride, reduced high-density lipoprotein cholesterol (HDL-C), and elevated non-HDL-C levels, and increased triglyceride/ HDL-C ratio.This pattern worsens wit...

International Travel for Organ Transplantation: 2024 Multinational Survey of Routes, Organs, and Donor Types

BACKGROUND: International travel for organ transplantation (ITOT) reportedly affects ≥2% of global solid organ transplant activity, yet detailed information about ITOT participants, organ types, travel configurations, and clinical settings remains scarce. Previous research has fo...