Guilin Medical University

Preclinical toxicity and immunogenicity of a quadrivalent recombinant influenza hemagglutinin vaccine (SCVC101) in rhesus monkeys

SCVC101 is a novel recombinant hemagglutinin (rHA) protein-based quadrivalent seasonal influenza vaccine containing HA gene sequences of A/Wisconsin/588/2019 (H1N1) pdm09-like virus, A/Cambodia/e0826360/2020 (H3N2)-like virus, B/Washington/02/2019 (B/Victoria lineage)-like virus,...

Effects of sun-drying and steaming on Ehretia macrophylla Wall. (EMW) fruit polysaccharides: structure, physicochemical properties and gut-related functions

Pectin-like polysaccharides from Ehretia macrophylla Wall. fruit (EMWFP) remains scarcely explored; their macromolecular structures are highly responsive to traditional post-harvest processing. Using in vitro digestion-fermentation models and structural analyses, this study provi...

Correlation between the red blood cell distribution width to albumin ratio and mortality rate in patients with bronchial asthma

The red blood cell distribution width-to-albumin ratio (RAR) has emerged as an important biomarker for evaluating the prognosis of several respiratory diseases. However, there is currently limited research on the correlation between RAR and mortality in patients with bronchial as...

DeCyReM: De-Cycled Residual Memory with Utility-Gated Retrieval for Traffic Flow Forecasting

Accurate traffic-flow forecasting remains challenged by abrupt and irregular states even after dominant periodic patterns are captured. Existing predictors model the resulting difficult errors implicitly through their parameters and cannot explicitly reuse specific historical err...

MURECAST: Memory-Based Utility-Aligned Residual Evidence with Calibrated Activation for Selective Correction of Traffic-Flow Forecasts

Short-term traffic-flow forecasting predicts road-network states, yet spatio-temporal predictors can leave structured, context-dependent residuals. They are seldom reused at inference, while similarity-based transfer can introduce corrections that increase error. We propose Memor...

The ATC score: a novel efficacy scoring model for risk stratification and personalized management of unresectable HCC patients receiving TACE-lenvatinib-PD-1 inhibitor therapy

Unresectable Hepatocellular Carcinoma (uHCC) has limited therapeutic options. The combination therapy of Transarterial chemoembolization (TACE), lenvatinib, and PD-1 inhibitors (T-L-P) shows promising efficacy, but a tool to predict individual treatment responses is lacking. To d...

Integrative transcriptomic and machine learning analyses identify NOL7 and TXLNA as candidate blood biomarkers for Parkinson’s disease within an RNA modification-associated co-expression network

Abstract Background Parkinson’s disease (PD) pathogenesis involves complex molecular mechanisms, with emerging evidence implicating RNA modifications (RM). This study sought to explore RM-associated key genes and their roles in PD progression. Methods Transcriptomic datasets GSE6...

Aptamer-functionalized exosomes co-delivering miR-934 inhibitor and gemcitabine for targeted pancreatic cancer therapy

Pancreatic cancer remains a malignancy with limited treatment efficacy and high resistance to chemotherapy. miR-934 was identified as an oncogenic miRNA significantly upregulated in pancreatic cancer, promoting tumor progression, epithelial-mesenchymal transition (EMT), and chemo...

Additive manufacturing of advanced electronic devices: a comprehensive review of materials, processes, and applications

The additive manufacturing (AM) technology has gained recognition as an innovative technology that holds promise for transforming the electronics industry through the realization of complex designs and multi-material integration. Advances in additive manufacturing (AM) technologi...

Latent class analysis of sexual behavior and HIV testing profiles among sexually experienced college students in China: a cross-sectional online survey

Rising human immunodeficiency virus (HIV) infections among young people underscore the need to strengthen campus-based prevention. We used latent class analysis (LCA) to summarize sexual behavior and HIV-testing profiles among sexually experienced college students, examine associ...

BCL9 inhibition promotes fibroblast lipogenesis by regulating macrophage–fibroblast interactions to attenuate pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease with an urgent need for novel therapeutic strategies. M2 macrophage-derived TGF-β1 promotes fibroblast myogenesis, contributing to IPF pathogenesis. Targeting macrophage polarization and fibr...

Effects of Shade Treatments on Growth, Photosynthetic Performance, Leaf Microstructure, and Pigment Accumulation in Horsfieldia hainanensis Seedlings

In this study, three-year-old seed-derived seedlings of Horsfieldia hainanensis Merr. were subjected to 0%, 25%, 50%, and 75% shade treatments in a nursery shade-net experiment from October 2025 to June 2026. Each treatment included three replicates, with three seedlings per repl...