East China University of Science and Technology

Existence and multiplicity of normalized solutions to a large class of elliptic equations on bounded domains with general boundary conditions

Abstract In this paper, by adapting the perturbation method, we study the existence and multiplicity of normalized solutions for the following nonlinear Schrödinger equation { − Δ u = λ u + f ( u ) in Ω , B α , ζ , γ u = 0 on ∂ Ω , ∫ Ω u 2 d x = μ , ( P ) α , ζ , γ μ where Ω ⊂ R...

Multi-Chamber Dynamic Molecular Crystal Microcapsules for Payload Encapsulation and Controlled Release

Abstract Crystalline self-assembly offers a powerful route to ordered organic materials with well-defined structures and morphologies. Despite substantial advances in controlling crystal habit, organic single crystals with precisely engineered architectures, particularly those wi...

TROP2‐Targeting Chimeras (TRTACs) for Tumor Cell‐Selective Membrane Protein Degradation and Enhanced Drug Delivery

ABSTRACT Extracellular targeted protein degradation (eTPD) systems typically utilize lysosome‐targeting receptors (LTRs) to redirect extracellular and membrane proteins for lysosomal degradation. Expanding the repertoire of clinically relevant LTRs could broaden the therapeutic p...

Waste cooking oil to sustainable aviation fuel: A review of pretreatment technologies

The valorization of waste cooking oil (WCO) into sustainable aviation fuel (SAF) represents an important strategy for reducing the carbon footprint of the aviation sector. However, raw WCO is highly heterogeneous, containing triglycerides and diverse impurities (e.g., suspended s...

Design and Application of Imidazole-Based Hyper-Crosslinked Polymer-Stabilized Silver Nanoclusters for Wastewater Treatment

Abstract Stabilizing metal nanoclusters in porous organic frameworks while maintaining accessible mass-transfer pathways is essential for maximizing metal-site utilization in heterogeneous catalysis. Herein, we developed a clotrimazole-derived imidazole hyper-crosslinked polymer,...

Boosting the supercapacitive performance of NiCo metal-organic frameworks via the synergistic effect of oxygen vacancies and bismuth decoration

To fulfill the escalating demand for next-generation energy storage systems, designing supercapacitors with superior specific capacity, prolonged durability is imperative. Nonetheless, the practical implementation of most metal-organic frameworks in electrochemical storage is fre...

Mitotic assembly of respiratory supercomplexes ensures accurate cell division and fuels tumor growth

As cells progress from interphase into mitosis, fluctuating metabolic demands coincide with mitochondrial fission. However, the mechanisms by which mitochondria coordinate morphological changes and metabolic adjustments during mitosis remain poorly understood. Using proteomic ana...

Evolutionary Rewiring of Sugar Transporter Gene manXYZ Enables Highly Coordinated Non-glucose Metabolisms in Engineered Lactic Acid Bacterium

Abstract Achieving highly coordinated metabolism and efficient conversion of lignocellulose-derived non-glucose sugars remains a major challenge for biorefinery microbial cell factories. Herein, we report an evolutionary rewiring of an engineered lactic acid bacterium Pediococcus...

Self-Healing Core–Shell Interfaces Enabling Adaptive Solid-State Ion Transport Kinetics toward Highly Efficient Seawater Lithium Extraction

Abstract The surging global demand for lithium poses increasing challenges to supply security and sustainability. However, seawater lithium extraction technology with high selectivity and high extraction rate has not yet been developed due to extremely low lithium ion concentrati...

Hydrogen‐Bonding‐Stabilized Organic Piezoelectric Nanofibers for Immunogenic Sonopiezodynamic Therapy of Metastatic Tumors

ABSTRACT Piezoelectric biomaterials enable mechano‐electrical coupling in biological systems, facilitating real‐time sensing, actuation, and in vivo energy harvesting. However, their application is constrained by the scarcity of stable organic piezoelectric systems. Here, we deve...

Surfactant-Mediated Enantioselective Extraction: Interfacial Behavior Investigation from a Microscopic Perspective

Abstract Enantioselective liquid–liquid extraction (ELLE) based on cyclodextrin host–guest recognition is a promising green strategy for chiral resolution. However, its industrial application is often hindered by restricted chiral recognition efficiency and ill-defined interfacia...

ncAA-RepDistill: a chemistry-native SMILES representation for permeability prediction and local edit ranking of non-canonical cyclic peptides

Non-canonical amino-acid (ncAA) cyclic peptides occupy a chemically rich design space for tuning permeability, stability, and bioavailability, but they remain difficult to model because local chemical edits are strongly scaffold-dependent. Existing representation strategies addre...

Hydrogen‐Bonding‐Stabilized Organic Piezoelectric Nanofibers for Immunogenic Sonopiezodynamic Therapy of Metastatic Tumors

ABSTRACT Piezoelectric biomaterials enable mechano‐electrical coupling in biological systems, facilitating real‐time sensing, actuation, and in vivo energy harvesting. However, their application is constrained by the scarcity of stable organic piezoelectric systems. Here, we deve...

Sustainability assessment of China's nitrogen-phosphorus cycling system under future carbon neutrality transition scenarios

Achieving sustainable management of the nitrogen–phosphorus (N–P) cycling system is essential for advancing multiple United Nations Sustainable Development Goals, yet its long-term sustainability under carbon neutrality transition pathways remains insufficiently understood. This...

Enhanced production of phomapyrrolidone a through culture-condition optimization and morphological regulation in Didymella sp. FATR0054

Phomapyrrolidone A (Ppd A) is a hirsutellone-type macrocyclic alkaloid derived from marine fungi, exhibiting significant activity against triple-negative breast cancer (TNBC). However, its low fermentation yield has limited further drug development. This study established a syste...

Generalized Tricomi–Gaussian Beams as a Structured Light Framework Enabled by Liquid‐Crystal Geometric‐Phase Polymer

ABSTRACT Tailoring the high‐dimensional degrees of freedom of structured light is central to modern photonics. However, existing descriptions often treat beam morphology, propagation dynamics, and topology separately, limiting a unified view of structured‐light evolution. Here, w...

Synergistic regulation strategy: NiO/g-C3N4 promoting efficient prelithiation of Li2C2O4

Lithium oxalate is regarded as a promising cathode prelithiation additive for compensating irreversible active lithium loss during the initial cycle of lithium-ion batteries, owing to its high theoretical specific capacity, good air stability, and low cost. However, its intrinsic...

CGA-DTA: interaction-conditioned graph topology and cross-graph attention for drug--target affinity prediction

Drug–target affinity (DTA) prediction supports virtual screening in computer-aided drug discovery, but graph-based models still face two linked limitations. Adaptive-topology methods usually learn drug and protein graphs independently and merge them only at the prediction head, w...

Neighboring-aware optimization for end-to-end detection transformer

The Transformer-based DETR framework has achieved end-to-end set prediction, driving technological innovation in the field of object detection. However, it has two key limitations: First, the cost function overlooks semantic similarity between queries and targets, and the Hungari...

What Contributes to Self‐Efficacy in Speaking Chinese as a Foreign Language: A Social Cognitive Perspective

ABSTRACT Grounded in social cognitive theory, this study investigated how high‐evidence factors jointly contribute to Chinese‐as‐a‐foreign‐language (CFL) speaking self‐efficacy. Data from 236 CFL learners in Beijing revealed a multifaceted pattern of associations. Speaking strate...