Dr. D. Y. Patil Medical College, Hospital and Research Centre

Antitubercular evaluation and synthesis of fused pyrano-thiazole-2-one derivatives via green and efficient protocol

Tuberculosis has become one of the leading causes of mortality worldwide. In developing countries, tuberculosis is one of the 10th leading causes of death, highlighting the urgent need for antitubercular drugs. In this study, we synthesized fused pyrano-thiazole-2-one derivatives...

Resilience and Disparity: A statistical reevaluation of the pandemic-era self-harm crisis using Global Burden of Disease data (1990–2023)

Background Early models projected pandemic-driven increases in suicide and violence. This study utilizes Global Burden of Disease (GBD) 2023 data to evaluate mortality trajectories for self-harm and interpersonal violence (1990-2023), assessing regional and demographic pandemic-e...

Case report on Vitamin B6-Responsive Gyrate atrophy with Cystoid Macular Edema in a Consanguineous Young Male: A Treatable Metabolic Retinopathy

Abstract Gyrate atrophy is a rare autosomal recessive chorioretinal dystrophy caused by ornithine aminotransferase deficiency, resulting in toxic accumulation of plasma ornithine and progressive retinal degeneration. We describe a 20-year-old male, born to consanguineous parents,...

Giant Mesenteric Angioleiomyoma: A Rare Case Report

ABSTRACT: Angioleiomyomas are rare benign tumors of smooth muscle primarily originating from blood vessels. This tumor displays a distinctive histological pattern characterized by bundles of spindle-shaped smooth muscle cells arranged around numerous small vascular spaces. The di...

Two Forgotten Ipsilateral Double J Stents Managed in a Single Session: A Rare Endourologic Challenge

ABSTRACT: Forgotten ureteral stents may lead to severe complications such as encrustation, infection, obstruction, and stone formation, especially when retained beyond 12 weeks. Dual forgotten stents in the same renal system managed in a single operative session are rare. A 51-ye...

Exploring effect of excitation wavelength on upconversion emission in Nd, Yb, Er and Ho tetra co-doped Y2O3 phosphor and use in optical thermometry

This paper examines the effects of excitation wavelength, power, and temperature on the upconversion (UC) emission of phosphors prepared by doping Y 2 O 3 with combinations of four rare earth ions (Nd 3+ , Yb 3+ , Er 3+ , and Ho 3+ ) synthesised via the combustion route. Structur...

Coinfection of Two Endemics – Scrub Typhus and Malaria

ABSTRACT: Malaria and scrub typhus are both significant causes of acute febrile illness in the Indian subcontinent. Due to their overlapping clinical manifestations, it can be a challenge to distinguish between the two. Coinfection, although rarely seen, may lead to greater disea...

As India expands HPV vaccination for girls, inclusion of boys deserves consideration

Human Papilloma Virus (HPV) infection is Commonly associated with cervical carcinoma; however, HPV affects both female and male and contributes to a broad spectrum of diseases. HPV infection can cause benign conditions such as genital warts as well as HPV-associated malignancies,...

Age Cohort Patterns of Socioeconomic Inequalities in High-Risk Body Mass Index (BMI) and Waist to Hip Ratio (WHR) Composite: Findings from Nationally Representative Survey

<title>Abstract</title> Background Obesity is a growing global health challenge, with central adiposity posing particularly high cardiometabolic risk. In low- and middle-income countries (LMICs) like India, the coexistence of undernutrition and obesity reflects a double burden of...

Beyond Diagnosis: Why Clinical Curiosity Still Matters in Psychiatry

Abstract Clinical curiosity has historically been a defining characteristic of psychiatric practice. Beyond the collection of symptoms and assignment of diagnoses, psychiatry has traditionally sought to understand patients’ subjective experiences, developmental histories, interpe...

Deepfakebuster: a confidence-calibrated adaptive ensemble framework for robust Deepfake image detection

Advances in the realism of synthetic media created with generative adversarial networks (GANs), diffusion models, and face manipulation tools has created an increased demand for well-established deepfake detection systems that can detect many different types of manipulation artif...

Telephone versus in-person administration of the Early Childhood Development Index 2030: a crossover study, Brazil, Canada, India and Malawi.

Objective: To examine agreement between telephone and in-person administration of the Early Childhood Development Index 2030 (ECDI2030) survey. Methods: -tests and intraclass correlation coefficients. Findings: : -0.36), regardless of modality. However, pooled and stratified intr...