Dicle University

Removal of Zn(II) from low concentration waters by adsorption method with activated carbon obtained from plant waste

Natural adsorbents derived from agricultural waste are considered sustainable and cost-effective solutions for removing heavy metals. This study investigated the adsorbent potential of grape seed waste-derived bioactive carbon (GSW-BAC) for removing zinc(II) ions from water. GSW-...

Protective Effects of Ethyl Pyruvate and Rutin Hydrate Against Colistin-Induced Nephrotoxicity in Rats

Background: Colistin is increasingly being used as a last-line treatment option for multidrug-resistant Gram-negative infections; however, its clinical use remains limited due to its nephrotoxic side effects. This study investigated the potential nephroprotective effects of ethyl...

Epigallocatechin Gallate Modulates the Cellular Response to Doxorubicin in HeLa Cervical Cancer Cells

Cervical cancer remains a major cause of cancer-related mortality worldwide, highlighting the need for strategies that may improve responses to conventional chemotherapeutics. Epigallocatechin gallate (EGCG), a green-tea polyphenol with diverse biological activities, has been inv...

Classification of mandibular impacted third molar teeth on panoramic radiographs using deep learning algorithms

This study aimed to evaluate the image-based technical performance of deep learning-based models in classifying impacted mandibular third molars on panoramic radiographs. Accurate identification of angular impaction patterns is essential for treatment planning, yet manual interpr...

Detection-Guided ROI-Constrained Diffusion for Weakly Supervised White Blood Cell Segmentation: A Retrospective Internal and External Dataset Evaluation

Background: Accurate white blood cell (WBC) segmentation is important for quantitative microscopic image analysis, but conventional supervised approaches depend on labor-intensive pixel-level annotations and may exhibit reduced robustness across datasets. This study proposes a de...

Comparative Phenolic Profiling (LC-ESI-MS/MS) of Different Extracts of Polygonum afyonicum with Soxhlet Extraction

Polygonum afyonicum Leblebici & Gemici is an endemic species that grows at high altitudes, forming a small shrub with a tendril-like growth pattern. This study was conducted to determine the phytochemical contents of the acetone and methanol extracts of this species. After identi...

Rosmarinic Acid Enhances Doxorubicin Activity in MDA-MB-231 Cells: Associations with Intracellular Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis

Background/Objectives: Rosmarinic acid (RA) is a naturally occurring polyphenolic compound with promising anticancer activity; however, its potential to enhance the therapeutic efficacy of doxorubicin (DOX) against triple-negative breast cancer (TNBC) has not been comprehensively...

Cytotoxic, Drug-Interaction, and Apoptosis-Associated Effects of β-Boswellic Acid and Doxorubicin in Murine 4T1 TNBC-like Cells

Background/Objectives: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited targeted therapeutic options. Although the anticancer and pro-apoptotic properties of boswellic acids have previously been reported, the interaction profile of chemical...

Real-World Outcomes of Second-Line Chemotherapy in Metastatic Urothelial Carcinoma

Second-line chemotherapy is widely used in metastatic urothelial carcinoma after progression on first-line platinum-based therapy, but its independent contribution to survival, as opposed to selection of healthier patients, remains unclear. In this multicenter retrospective cohor...

Intelligent Type-3 ANFIS-based adaptive secondary control for parallel grid-forming inverters in islanded smart microgrids

Abstract This article presents an adaptive secondary control method for islanded AC microgrids using an Enhanced Type-3 Adaptive Neuro-Fuzzy Inference System (T3-ANFIS). The considered microgrid structure consists of two parallel grid-forming (GFM) inverters operating under diffe...

The psychosocial resilience experiences of healthcare workers following the 2023 Kahramanmaraş earthquakes: a qualitative study

This study explores the under-researched experiences of healthcare workers navigating a “dual-role” paradox, functioning simultaneously as traumatised disaster survivors and active responders during the 2023 Kahramanmaraş Earthquakes. Disasters fracture a community’s social fabri...

Antioxidant, Anti‐Quorum Sensing and Enzyme Inhibitory Activities of Dryopteris raddeana and Molecular Docking Studies

ABSTRACT Dryopteris species grow widely in many countries and exhibit a wide range of bioactive properties. Studies on one of these species, Dryopteris raddeana , are quite limited. In this context, it was aimed to evaluate the antioxidant, antidiabetic, antiobesity, and anti‐quo...

A Preliminary Food–AI Readiness Framework for AI-Enabled Hyperspectral Systems in Fungal and Mycotoxin Risk Management: A Critical Narrative Review

Fungal contamination and mycotoxins remain important hazards in cereal, nut, oilseed, and processed-food chains. For grain handlers, processors, storage facilities, quality-assurance laboratories, and technology developers, the practical challenge is not only detection but determ...

Attention-gated hybrid ANN–TCN–BiLSTM framework with explainable AI for operational efficiency classification in PV–EV microgrids

The increasing integration of photovoltaic (PV) generation and electric vehicle (EV) charging infrastructure into microgrids creates operational challenges arising from renewable intermittency, stochastic charging demand, and varying grid dependence. This study proposes an explai...

Association of Periodontal Disease with Sleep Quality and Oral Health-Related Quality of Life: A Cross-Sectional Study

Background/Objectives: This study aimed to comprehensively evaluate the interaction between periodontal disease, sleep quality, and quality of life and to investigate the effects of the presence and severity of periodontal disease on individuals’ sleep patterns and oral health-re...

Rosmarinic Acid Potentiates Cisplatin-Induced Antitumour Activity Through ROS-Associated Apoptotic Signalling in Two- and Three-Dimensional Breast Cancer Models

Triple-negative breast cancer (TNBC) remains a highly aggressive malignancy with limited therapeutic options and frequent resistance to platinum-based chemotherapy. Rosmarinic acid (RA), a naturally occurring polyphenol, has attracted considerable interest as a potential chemosen...

Impact of adjuvant endocrine therapy on disease-free survival in early triple-positive breast cancer: a multicenter retrospective cohort study of the Turkish oncology group

Triple-positive breast cancer (TPBC), characterized by concurrent ER, PR, and HER2 positivity, poses unique therapeutic challenges due to ER–HER2 crosstalk. The optimal adjuvant endocrine therapy in TPBC patients receiving anti-HER2 regimens remains poorly defined. This multicent...