Dartmouth College

Why Is the Mental Health of the Youngest American Workers in Decline?

The worsening mental health of young workers drives what appeared to be the disappearance of the age-related U-shape in wellbeing and the hump-shape in illbeing over the last decade. Using repeat cross-sectional data, we show that, whilst illbeing remains hump-shaped among non-wo...

The Star Formation History and Evolution of the Ultra-Diffuse M81 Satellite F8D1

Abstract We present deep Hubble Space Telescope (HST) imaging of one of the nearest ultra-diffuse galaxies (UDGs) outside of the Local Group: F8D1, a satellite of M81 known to be tidally disrupting. UDGs are an enigmatic and diverse population, with evolutionary pathways ranging...

Real-Time Symptom and Wearable Monitoring May Improve Prediction of Postoperative Recovery in Lumbar Spine Surgery Beyond Standard Measures

BACKGROUND AND OBJECTIVES: Accurately identifying candidates likely to benefit from surgery and addressing modifiable preoperative risk factors are central to optimizing outcomes. Current prediction tools often rely on static clinical data and patient-reported measures, which lac...

Louis IX’s letter to the French of August 1250 (Part 1): a new edition and translation

Louis IX’s letter to the French, written from Acre in 1250 upon the king’s decision to delay his return to France, is one of our key sources for the events of Louis’ crusade to Egypt in 1249-1250. The received text of the letter goes back to a mid-thirteenth-century manuscript (B...

Host DNA repair factors empower a mechanism of antiviral nucleoside analog resistance

ABSTRACT How host functions affect resistance to antiviral drugs is poorly understood. Ganciclovir, a chain-terminating nucleoside analog, is a first-line therapy against human cytomegalovirus, a widespread herpesvirus that causes life-threatening disease in immunocompromised ind...

Kernel smoothing operators on thick open domains

We study the convergence properties of a general family of normalized Markovian kernels on a domain $$\Omega$$ in the Euclidean space. Based on the notion of a thick set we show that a local Hardy-Littlewood inequality holds in $$L^p(\Omega)$$ , $$p \in (1, \infty]$$ when $$\Omeg...

Understandingthe Electronic Structure of RutheniumOxides during Redox Cycling with High Energy Resolution X-rayAbsorption Spectroscopy

Abstract Ruthenium oxides are essential catalysts and charge storage materials whose performance across reactions, from the oxygen evolution reaction to the chlor-alkali process, depends critically on reversible Ru redox cycling and the associated electronic structure changes. Al...

Light‐Cone Shell Queries for Scalable Time‐Gated Rendering

Abstract Monte Carlo time‐gated rendering requires sampling light paths that not only connect a sensor to an emitter, but which also have a total travel time that falls within a narrow interval, a constraint that is difficult to importance sample. We show that this problem has an...

Innate immune recognition of Debaryomyces hansenii requires Dectin-1-Card9 signaling

ABSTRACT Innate immune signaling plays a key role in host response to infection, yet the pattern recognition receptors that detect non-model gut-associated yeasts remain poorly defined. Here, we investigated macrophage sensing of Debaryomyces hansenii , a food-derived yeast that...

Maternal influenza vaccination boosts durable breast milk antibody-mediated protection in infants

Influenza contributes to significant disease burden worldwide, and young infants are at an increased risk of severe influenza infection. Maternal antibodies transferred across the placenta and through breast milk confer anti-influenza immunity to the newborn. Placental transfer p...

Plants, soil, and coexistence: an alternative approach to modelling plant-soil feedback

Abstract Background and Aims Plant-soil feedback (PSF) affects plant coexistence and diversity. Although the current paradigm provides a direct experimental method to quantify PSF and explains coexistence with varying levels of success, the emphasis on pairwise interactions hinde...