Dalian University

A modular in vitro multienzyme cascade for the sustainable synthesis of high-value vidarabine 5′-monophosphate from adenosine

Nucleoside analogues such as vidarabine (Ara-A) are vital therapeutics but are often limited by poor pharmacokinetics. Its phosphorylated form, vidarabine 5′-monophosphate (Ara-AMP), offers improved solubility and is used as a clinical alternative, although it can be dephosphoryl...

A sliding mode control strategy for chaos suppression in power systems of arbitrary dimensions

Power systems are prone to chaotic oscillations. Conventional sliding-mode controllers are tightly coupled with system dimensions, and the control law needs to be redesigned once the system order changes. This paper proposes a recursive sliding-mode control method independent of...

A Fatigue Life Prediction Method Based on Optimized Data Augmentation Algorithm and Adaptive Sampling Model

ABSTRACT Machine learning–based fatigue life prediction is essential; yet their datasets typically contain fewer than 50 samples, severely challenging predictive modeling. This study proposes an integrated framework of simulated annealing (SA)‐guided data augmentation and residua...

Blood flow restriction of sport-specific repeated-sprint training enhances acute physiological responses in elite female boxers: a randomized, crossover trial

This study investigated the acute physiological responses during sport-specific repeated sprint training with different levels at blood flow restriction (BFR) in elite boxing athletes. Sixteen female boxers participated in this randomized, cross-over study. All boxers conducted f...

Biomechanical analyses point to dense collagen fibre architecture in an Ediacaran frond

Ediacaran macrofossils record the earliest large and complex organisms on Earth. Despite extensive study, fundamental aspects of their internal anatomy and tissue composition remain poorly known, limiting understanding of how these organisms were constructed and functioned, as we...

Electrical insulation enhancement of the Al 2 O 3 composite films at high temperature by oxygen vacancy suppression

Abstract The electrical insulation film is critical for the reliable operation of Ultra-high temperature thin-film sensors (UTTSs) at elevated temperatures. However, the resistance of the insulation film easily decline at high temperatures due to the formation of the oxygen vacan...

Ammonium Chloride and Peroxide: A Metal‐Free Aqueous Strategy for Oxime Synthesis

A metal‐free, aqueous protocol enables the synthesis of oximes from carbonyls using NH 4 Cl and H 2 O 2 . A radical mechanism involving in situ hydroxylamine generation bypasses the use of unstable salts. Monoethanolamine (MEA) serves as an essential additive, facilitating the co...

Magnoflorine Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Targeting the NDUFV1 Subunit of Complex I to Regulate the ROS/AMPK Signaling Pathway

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent metabolic disorder with limited therapeutics. Magnoflorine (MAG), a natural alkaloid from edible plants, ameliorates MASLD; however, its direct targets remain unclear. Here, by integrating th...

Technology Push or Demand Pull? Supply-Chain AI Spillovers and the Quality of Green Innovation Toward Sustainable Production in Chinese Listed Firms

Artificial intelligence (AI) diffuses beyond adopting firms into the wider production network, yet the direction and quality of these spillovers remain underexplored, an omission that matters because only high-quality green innovation advances genuine sustainable transformation....

RobustSCI: Beyond reconstruction to restoration for snapshot compressive imaging under real-world degradations

Deep learning has greatly advanced video Snapshot Compressive Imaging (SCI), but most existing methods are developed for reconstructing videos from relatively clean or idealized compressive measurements. In practical capture, motion, low illumination, and sensor imperfections can...

The Development of Mandarin-Speaking Children’s Comprehension of Irony

This study examined age-related differences in irony comprehension among 168 Mandarin-speaking children aged 6–10 years. Each child watched four illustrated stories with prerecorded audio: one literal, one deception, and two irony stories. For each irony story, children judged th...

Velocity adaptive preview path tracking control for autonomous vehicles using deep reinforcement learning with Lyapunov function-based reward shaping

Traditional rule-based path tracking controllers of autonomous vehicles (AVs) often struggle with nonlinear vehicle dynamics, parameter tuning, and changes in road conditions. Learning-based methods partly address these issues, but remain limited in adapting to velocity changes,...

Catalyst design in heterogeneous deuteration: recent advances and perspectives

Deuterium-labeled compounds have become indispensable across pharmaceutical research and development, analytical testing, and materials science, driving urgent demand for efficient deuteration methodologies. However, current synthetic routes are frequently constrained by high cos...

Regioselective 1,2-Hydroamination of Conjugated Enynes for Accessing Propargylamines via Dual Photoredox/Cobalt Catalysis

Abstract The photoredox-catalyzed selective addition of N–H bonds across unactivated 1,3-enynes represents a promising and sustainable transformation, enabling efficient access to high-value-added propargylamines. Current state-of-the-art advancements via photoredox catalysis rel...

Catalytic Performance of Post-Treated Thin-Plate ZSM-5 for Allyl Alcohol Etherification

Diallyl ether possesses unique chemical activities due to its dual functional allyl group and ether bond and is thus a high-value-added fine chemical with diverse applications. In this work, thin-plate ZSM-5 is synthesized and then subjected to alkaline post-treatment to improve...

Experimental investigation of inlet-temperature effects on energy separation in a Ranque–Hilsch vortex tube under pressure–temperature coupling

Inlet temperature directly determines the thermodynamic state of the working gas in a Ranque–Hilsch vortex tube (RHVT), but its role in pressure-driven energy separation remains insufficiently clarified, particularly under coupled variations in inlet pressure and cold mass fracti...

Discussion on Decompression Path and Wave Speed of Supercritical and Dense CO2 with Impurities

Decompression of dense and supercritical CO2 containing impurities was investigated using an equilibrium isentropic model coupled with NIST REFPROP 10 and GERG-2008. The pressure plateau was determined from the intersection of the isentropic path and the bubble line. The adopted...

Biomimetic Confined Crystallization of Large‐Sized Single‐Crystalline Multicomponent Mesoporous Metal Oxides

ABSTRACT The performance of mesoporous metal oxides (MMOs) depends strongly on the composition, crystallinity, and size. However, soft‐templating synthesis of multicomponent systems is typically constrained by poor structural control arising from phase separation, uncontrolled nu...

Experiences and self-management practices among hospitalized older adults with oral frailty: a qualitative interview study

To explore oral health experiences and self-management among hospitalized older adults with oral frailty, and to provide evidence to inform the development of targeted intervention strategies. Guided by the theory of health empowerment, a purposive sampling approach was adopted....

Method for improving robotic surface milling accuracy by stiffness optimization and force-induced error compensation

Purpose In robotic surface milling, the inherently low stiffness of industrial robots often leads to significant force-induced deformation errors and reduced machining accuracy. This study aims to propose a multi-factor optimization method that combines stiffness optimization wit...