Consejo Superior de Investigaciones Científicas

Supramolecular Mask-Mediated Regioselective bis-Bingel-Functionalization of M3N@I h -C80 (M = Lu, Sc)

Abstract Exohedral functionalization of endohedral metallofullerenes (EMFs) is essential for exploiting these intriguing molecules as novel materials in applications such as biomedicine and organic solar cell device design. In the case of trimetallic nitride template EMFs (TNT-EM...

Genomic and clinical landscape of RAS mutations in acute myeloid leukemia

RAS mutations are recurrent in acute myeloid leukemia (AML); yet, their genomic and clinical landscape remain poorly characterized. We analyzed centralized molecular profiling data in 8,553 patients with newly diagnosed AML. Of these, 1,775 (21%) harbored RAS mutations: NRAS in 1...

A Diamagnetic Six-Coordinate Ag(III) Complex

Abstract The octahedral complex AgIII(CF3)3tpy (2Ag), attainable from AgIII(CF3)3py (1Ag) and terpyridine (tpy), has been isolated and characterized using NMR spectroscopy and Sc-XRD. Strikingly, 2Ag proved to be diamagnetic and showed tridentate coordination of the tpy ligand, t...

Cosmological Constraints from Full-scale Clustering and Galaxy–Galaxy Lensing with DESI DR1

Abstract We present constraints on cosmic structure growth from the analysis of galaxy clustering and galaxy–galaxy lensing with galaxies from the Dark Energy Spectroscopic Instrument (DESI) Data Release 1. Our analysis includes four samples drawn from the Bright Galaxy Survey (B...

Conflict Legacies in Wild Edible Plant Use Across Acholi and Lango Communities in Northern Uganda

Wild and semi-wild edible plants (WEPs) are critical sources of nutrition, food security, and biocultural heritage in rural communities globally. This study investigates the diversity, use, and drivers shaping differences in WEP knowledge and diversity between Lango and Acholi co...

Integrating Drug Physicochemistry and Hfq-Dependent Regulation of Ciprofloxacin Accumulation in Escherichia coli

Ciprofloxacin (CIP), an amphoteric fluoroquinolone, undergoes pH-dependent changes in protonation state that influence membrane permeability and intracellular accumulation. Here, we investigated how drug physicochemistry and bacterial regulatory pathways jointly determine CIP acc...

Beyond Principlism: A Cosmopolitan and Care Ethics Approach to One Digital Health

Abstract This article examines the limitations of principlism in addressing the ethical challenges posed by One Digital Health. While principlism remains influential in bioethics, digital health, and global health policy, we argue that it is insufficient to capture the relational...

Optimization of atmospheric pressure plasma treatment for enhanced adhesion performance of microporous EVA

Atmospheric pressure plasma treatment (APPT) is a versatile technique for modifying polymer surface properties and improving adhesion in industrial applications. This study investigates a specific and industrially relevant system: microporous ethylene-vinyl acetate (EVA) bonded t...

Structure–Redox–Magnetism Dynamics Induced by Pd–Fe Interaction in Mixed Iron Oxide Nanoparticles

Abstract The incorporation of noble metals into iron oxide nanomaterials represents an effective strategy to tailor their redox and structural properties through metal-oxide interactions. However, a detailed experimental understanding of these effects is limited. This work invest...

Joint Modeling of GD-1 and C-19 as Old Streams

Abstract DESI observational data for the GD-1 and C-19 streams are compared to stream simulations in an evolving multihalo potential of a Milky Way–like galaxy based on a cosmological Milky Way–like simulation. The number of subhalos decreases with time, and the subhalo-stream en...

Targeted DNA Sequencing Reveals Distinct Rare-Variant Profiles in Pulmonary Hypertension Associated with Chronic Lung Diseases

The mechanisms underlying the development and severity of pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) remain poorly understood. To investigate the contribution of genetic factors, we performed targeted sequencing...

Chemical characterization and source apportionment of PM 10 in Belgrade, Serbia: influence of local and regional anthropogenic and natural sources

Abstract. Substantial efforts and improvements in air quality across Europe lowered levels of air pollutants including particulate matter (PM) in the last decades. However, significant proportion of the European population still lives in areas exceeding WHO recommendations, espec...

Limited global awareness of invasive alien species and little support for their management

Invasive alien species (IAS) are one of the main drivers of global change and can cause a wide range of negative ecological and social impacts. Addressing these impacts requires management actions, which can fail to be effective when not supported by the public. Here, we conducte...

Breaking the Blend: A multi-tracer kinematic decomposition method for IFS data applied to disentangling the AGN outflow and circumnuclear ring in NGC 5728 with JWST

Abstract Integral field spectroscopy (IFS) of the central kiloparsecs of active galactic nuclei (AGN) reveals a mixture of spatially coincident emission from star-formation and AGN feedback exciting the interstellar medium. Disentangling these components remains a challenge, as m...

Getting into the guts of eating disorders in children and adolescents, with a perspective from psychoneuroimmunology (the PSYNIGED study): an observational, longitudinal study protocol

Abstract Background Eating disorders (ED) are severe and complex psychiatric conditions characterized by the presence of abnormal eating patterns. An integrative biopsychosocial model has been developed to describe vulnerability to developing an ED, as well as its maintenance and...

Is Intercropping Viable in Rainfed Olive Systems? A Systematic Review and a Scope-Weighted Multilevel Analysis

Rainfed olive groves across the Mediterranean basin are increasingly threatened by prolonged droughts, soil erosion, shifting climate patterns, and lower profit margins, which undermine their long-term yields and viability. Incorporating agroforestry practices, specially intercro...

The Composite Spectrum of QSO Absorption Line Systems in DESI DR2

Abstract We present details regarding a composite spectrum of quasar (QSO) absorption line systems. In this composite spectrum, we identify more than 70 absorption lines and observe oxygen and hydrogen emission features at a higher signal-to-noise ratio than any previous study. A...

Insect outbreak progression over three years shapes biogenic volatile emissions in a mountain birch forest

Abstract Geometrid moth outbreaks are important natural disturbances in mountain birch ( Betula pubescens ssp. czerepanovii ) forests of northern Fennoscandia and are expected to intensify with climate change. Impacts of these outbreaks and moth herbivory on biogenic volatile org...

Short-lived halogen sources and chemistry in the Community Earth System Model v2 (CESM2-SLH)

The implementation of short-lived halogen (SLH) sources and atmospheric chemistry in the Community Earth System Model v1 (CESM1) allowed to study the influence of SLH chemistry on the oxidative capacity of the atmosphere and, consequently, the Earth's climate. In this manuscript,...

Thioredoxin h1-targeted proteins in European beech (Fagus sylvatica L.): Insights into metabolic control, stress response, and seed longevity

Seed viability and longevity underpin forest regeneration under changing environmental conditions. European beech ( Fagus sylvatica L.) produces intermediate seeds that gradually lose viability during storage, largely through oxidative stress, which makes redox homeostasis centra...