Comenius University Bratislava

Vascular Rings as a Cause of Respiratory Difficulties

Background: Vascular rings are rare congenital developmental anomalies of the cardiovascular system that present with variable respiratory and gastrointestinal symptoms often refractory to what is considered a standard treatment. The aim of our study was to describe the clinical...

Application of Extracellular Vesicles in the Diagnosis and Treatment of Cardiovascular Diseases

Paracrine signalling is considered an important mechanism underlying the therapeutic effects of cell-based therapies in cardiovascular diseases. Consequently, research in regenerative medicine has increasingly shifted its focus beyond conventional cell-based therapeutic strategie...

Event-Specific Kinematics of the Free Aerial Cartwheel on the Balance Beam: Associations with Execution Quality and Single-Leg Jump Performance

The Free Aerial Cartwheel is a complex balance beam skill requiring precise coordination under a limited support surface. This study examined event-specific joint-angle characteristics of the Free Aerial Cartwheel and their associations with technical execution, single-leg counte...

AI-Augmented Digital Diagnostics in Minimally Invasive Dentistry: A Case Report on Clinically Occult Approximal Caries

Background: Approximal dental caries pose a persistent diagnostic challenge, as early lesions frequently remain clinically occult beneath intact enamel surfaces during routine visual–tactile inspection. This case report describes the clinical utility, limitations, and decision-ma...

A multicenter, prospective – retrospective, epidemiological study in Czech and Slovak minors with spinal muscular atrophy treated with nusinersen

Abstract Background We used the Czech REaDY registry to collect and analyse data of paediatric patients with spinal muscular atrophy (SMA) who received nusinersen for five years. By sharing the results, we aim to increase healthcare professionals’ knowledge about this therapy. Re...

The herpetofaunal diversity of Takhar Province, Afghanistan

Takhar Province of Afghanistan was previously known to harbour only two species of amphibians and eight species of reptiles with no record of snake species. From 2020 to 2021, we collected herpetological data from the Province and identified 14 species and specimens representing...

Reconstruction of Evolutionary History of Pleurostomatid Ciliates (Ciliophora, Litostomatea, Haptoria): Interplay of Morphology and Molecules

Vďačný, Peter, Rajter, Ľubomír, Shazib, Shahed Uddin Ahmed, Jang, Seok Won, Kim, Ji Hye, Shin, Mann Kyoon (2015): Reconstruction of Evolutionary History of Pleurostomatid Ciliates (Ciliophora, Litostomatea, Haptoria): Interplay of Morphology and Molecules. Acta Protozoologica 54...

The Paradox of Medical Education: Lifestyle and the Sense of Self-Efficacy and Locus of Health Control Among Medical Students in the Eastern Borderlands of the European Union

Abstract Aim This cross-sectional study evaluated health behaviors, diet, physical activity, and psychological determinants (self-efficacy, life satisfaction, health locus of control) among medical and health sciences students across seven EU borderland countries to investigate t...

Clinical Management After Rupture of Silicone Gel-Filled Breast Implants in a Surgically Treated Cohort: A Retrospective Study

Objective: Breast implant rupture is clinically significant complication that is often asymptomatic making diagnosis challenging. The primary objective of this study was to describe the clinical presentation, preoperative imaging findings, and operative findings in this surgicall...

Integrated Structural, Physicochemical, Pharmacokinetic and Pharmacodynamic Evaluation of Substituted Phenylcarbonyloxypiperazinopropanols as Antimycobacterial Agents

This research aimed to evaluate structural, physicochemical and pharmacokinetic characteristics of racemic 2-hydroxy-3-(4-phenylpiperazin-1-yl)propyl 4-[(alkoxycarbonyl)amino]benzoates (Ib)–(IVb) and 2-hydroxy-3-[4-(R-substituted phenyl)piperazin-1-yl]propyl 4-[(alkoxycarbonyl)am...

Servile self-translation for Nazi Germany

Abstract This article contributes to the intersection of translation studies and fascist studies by shifting attention to translation as a component of cross-regime interaction within the cultural diplomacy of fascist “New Europe” as a network of power asymmetries and its underex...

Prevalence of Pelvic Girdle Pain in Postpartum Women in Slovakia: A Cross-sectional Study

Pelvic girdle pain (PGP) is a prevalent condition during the postpartum period that significantly affects functional mobility and quality of life. The aim of this study was to determine the prevalence of PGP among postpartum women in Slovakia (12 weeks to 1 year postpartum) and t...

Forensic analysis of an unwitnessed fatal diving accident using in-water investigative reconstruction

Unwitnessed diving fatalities present significant challenges for forensic investigation. We describe a fatal diving accident involving a 32-year-old experienced female diver during a deep night dive in freshwater. The diver became separated from her buddy and was recovered at dep...

Plasma neurofilament light chain in type 2 diabetes: Associations with diabetic peripheral neuropathy, age, and renal function in a pilot cross-sectional study

Background Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus (T2DM). Neurofilament light chain (NfL) is a circulating marker of neuroaxonal injury, but its interpretation may be influenced by age and renal function. Objective To evaluate th...

Natural Bioactive Compounds in Rheumatoid Arthritis: Experimental Evidence from Adjuvant Arthritis Model Supporting Combination Strategies with Methotrexate

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that represents continuous synovial inflammation, oxidative stress, immune dysregulation, and progressive cartilage degradation and bone erosion. Although disease-modifying antirheumatic drugs (DMARDs), includ...

Cerebral Small Vessel Disease and Sleep-Disordered Breathing in Patients with Acute Intracerebral Haemorrhage: A Prospective Two-Centre Observational Study

Abstract Background Intracerebral haemorrhage (ICH) is the second most common stroke subtype and carries high mortality and disability. Cerebral small vessel disease (cSVD) and sleep-disordered breathing (SDB) are mechanistically linked and both implicated in ICH pathogenesis, ye...

Successful Surgical Repair of a Window Ductus and Ventricular Septal Defect in a Neonate Utilizing Preoperative Three-Dimensional Modeling

Window ductus (WD) is a very rare and anatomically distinct variant of patent ductus arteriosus, also known as a type B patent ductus arteriosus. We report the case of a neonate who was born with a rare triad of congenital heart defects including a large WD, multiple ventricular...

Lifestyle-Related Predictors of Mental Well-Being and Depressive Symptoms among Young Adult Students at a Slovak University

Mental health problems among university students represent an increasing public health concern worldwide. The aim of this study was to assess mental health and identify lifestyle-related factors associated with mental well-being and depressive symptoms among university students i...

Thermal and optical characterization, as well as photostability assessment of sunscreens by using photoacoustic and photopyroelectric techniques

Sunscreens are fundamental public health tools for mitigating the harmful effects of ultraviolet (UV) radiation on the skin. UVA radiation reaches the Earth's surface in greater proportion, contributing to photoaging and skin carcinogenesis. In this context, the efficacy of sunsc...

Prevalence of Cardiovascular Risk Factors and Global Cardiovascular Risk Among Patients in General Practice: A Cross-Sectional Study

Abstract Introduction: Cardiovascular diseases (CVDs) remain the leading cause of mortality, morbidity, and healthcare expenditure worldwide, including Slovakia. The prevention of CVD is a cornerstone of modern preventive medicine. Recent epidemiological data highlight the ongoin...