Christian-Albrechts-Universität zu Kiel

Artificial Agents as Leaders and Followers: An Integrative Role-Congruity Review

Artificial agents such as algorithms, virtual agents, and robots increasingly occupy organizational roles as leaders, followers, and partners. However, evidence on how people evaluate these nonhuman role occupants is mixed. We systematically review 107 empirical studies across ma...

Motivated Procrastination

This study provides a rigorous empirical test for motivated memory as a cause for procrastination. In a longitudinal experiment over four weeks, individuals had to complete a cumbersome task of unknown length and receive noisy signals about their assigned workload. Varying scope...

Metascience, Research Software, and the Case for RS Metascience: Extended Preprint

Metascience is the study of science itself, including how scientific research is conducted, evaluated, and improved. Rather than asking questions about the natural or social world, metascience asks questions about scientific research -- its methods, objects of study, participants...

Metascience, Research Software, and the Case for RS Metascience: Extended Preprint

Metascience is the study of science itself, including how scientific research is conducted, evaluated, and improved. Rather than asking questions about the natural or social world, metascience asks questions about scientific research -- its methods, objects of study, participants...

Psychotherapy remission prediction models show limited cross-clinic generalizability in routine outpatient care

Abstract Clinical prediction models for psychotherapy outcomes have the potential to assist therapists in planning a patient’s individual treatment, but their clinical utility depends on maintaining predictive performance across settings. We assessed prediction of post-treatment...

AI-based smoke removal in robotic urooncologic surgery: a clinical pilot study

Abstract Surgical smoke from electrocautery limits visibility during robot-assisted oncological surgery by obscuring tumor margins, blood vessels and anatomical landmarks. AI-based smoke removal demonstrated promising technical performance, structured clinical evaluation remains...

Transoral robotic reconstruction of a posterior palatal defect using an upper arm flap following polymorphous adenocarcinoma resection: a novel minimally invasive approach

Abstract Background Surgical management of malignant tumors in the orofacial region frequently necessitates extensive resection, resulting in significant functional and aesthetic morbidity. In younger patients, these sequelae carry a substantial psychosocial burden, emphasizing t...

A high-resolution, multi-method palaeoenvironmental record from pan sediments at Maralaleng Pan, southern Kalahari basin

Human traces in semi-arid environments such as the Kalahari have been linked to the presence of water in the landscape. However, low organic preservation and an uneven distribution of studied sites have resulted in a gap in the knowledge of the environmental conditions under whic...

Flying through the plasmasphere to optimize low-energy ion measurements

The Juice flyby of Earth in August 2024 gave us the first chance to evaluate the performance of the Jovian Plasma Dynamics and Composition analyzer (JDC) in environments similar to those expected at Jupiter. JDC is one of the sensors belonging to the Particle Environment Package...

In situ XRD reveals terephthalate incorporation and phase evolution during reconstruction of zinc/aluminium and magnesium/aluminium layered double oxides under open air

This study examined the reconstruction of calcined layered double oxides, a widely used route for introducing bulky organic anions into layered double hydroxides. The timing of guest participation during initial layer reformation or later anion exchange remains unclear. This ques...

Belantamab mafodotin plus venetoclax in t(11;14)-positive relapsed or refractory multiple myeloma – the BELI(E)VE trial

Abstract Background Multiple myeloma (MM) is a widely incurable B-cell malignancy that predominantly affects older adults, representing 10% of hematologic cancers. Despite advancements in therapy that have significantly extended median overall survival (OS), MM remains a clinical...

The FraiLtx Study Protocol: A Prospective, Single-Center Observational Study on Frailty, Systemic Inflammation, and Monocyte Subsets in Liver Transplant Candidates

Introduction: Frailty is a multidimensional syndrome characterized by diminished physiological reserve and increased susceptibility to stressors, resulting in poor perioperative outcomes. While commonly associated with elderly patients, frailty is increasingly recognized in liver...

Aggregation framework for continuous digital health measures and application to walking activity data

Abstract No standardized procedures for aggregating continuous digital health measures exist. Using a modified Delphi approach, we developed a framework to standardize the selection of aggregations that provide clinically meaningful, stable values. This was applied to aggregate s...

Clustering without clusters: the meta-criterion and centroid reliability mistake continuous dynamics for discrete states

Microstate analysis starts with clustering and the meta-criterion is a heuristic to find an optimum cluster number. We address the following questions: (i) what number is found for non-cluster-forming dynamical systems, (ii) do centroids fall in random attractor regions, (iii) do...

Management of Acute Periodontal Conditions—The EFP S2k Level Clinical Practice Guideline

BACKGROUND: The European Federation of Periodontology (EFP) has developed Clinical Practice Guidelines (CPGs) for the treatment of periodontitis and for the management of peri-implant diseases. In accordance with the 2018 Classification, acute periodontal conditions are character...

MooBench: A micro-benchmark for performance overhead measurement of observability tools

MooBench: A micro-benchmark for performance overhead measurement of observability tools EventType Research Software Publication Abstract Understanding the runtime behavior of software is inherently difficult due to the unpredictability of the software's behavior itself and the no...

Effects of Microplastic Pollution on Growth, Photosynthesis, and Nutritional Composition of Maize ( Zea mays L.)

ABSTRACT Background Microplastic (MP) contamination in agroecosystems is an increasingly recognized environmental concern, whereas its polymer‐specific impacts on plant growth and nutritional composition remain poorly understood. Aim Our study aimed to evaluate how polymer type a...

Bonding with a Benchtop UV Ozone Cleaner: A Practical Guide to Prepare a Microfluidic Chip

This study describes a procedure for preparing microfluidic chips made from polydimethylsiloxane (PDMS) layers. It uses an Ossila UV ozone cleaner for surface activation instead of the more common oxygen plasma treatment. The process is limited to PDMS@PDMS bonding, and it can be...

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome—Results of the German Multicenter Study COGIA

ABSTRACT Introduction Diagnosis and treatment of children and adolescents with suspected Brugada syndrome (BrS) is challenging. Aim of the study was to evaluate the applicability of current diagnostic criteria for pediatric patients with suspected BrS in the German multicenter st...

Conserved protein folds underpin the diversification of secreted proteins in a fungal pathogen

Abstract Background During host colonization, fungal plant pathogens secrete effector-like proteins that alter host cell physiology and target plant-associated microbes. However, rapid evolution and low sequence conservation hinder the study and characterization of these proteins...