Centers for Disease Control and Prevention

Understanding rotavirus vaccine acceptance in Indonesia: a WHO BeSD-based exploration of parents' and religious leaders' perspectives in three provinces

Background Disparities in rotavirus vaccine uptake in Indonesia persist despite its national implementation, yet, the community-level determinants of vaccination remain underexplored. Understanding the behavioural and social factors influencing vaccination decisions is essential...

Healthy lifestyle as a protective factor against the risk of gastroesophageal reflux disease: Prospective population cohort analysis

Background Lifestyle modifications are recommended by American Gastroenterological Association (AGA) for managing gastroesophageal reflux disease (GERD), a significant health issue; but evidence is scarce. This study aims to investigate the longitudinal association between health...

Pneumococcal carriage and selected respiratory virus in children with clinical pneumonia in Salvador, Brazil during PCV10 era

Background In 2010, Brazil introduced the 10-valent pneumococcal conjugate vaccine (PCV10 GSK ). Assessing pneumococcal carriage among children with clinical pneumonia in the context of a mature PCV10 GSK program can inform decisions about use of next-generation PCVs. Methods We...

Changes in US Life Expectancy From 2019 to 2024

This cross-sectional study examines whether and how changes in drug-poisoning deaths were associated with changes in US life expectancy from 2019 to 2024.

Evaluation of the clinical performance of two new onchocerciasis rapid diagnostic tests in districts targeted for elimination in Ghana

Current diagnostic methods for onchocerciasis lack sufficient utility, sensitivity or specificity. Two new lateral flow assays developed by Bioaster and Global Access Diagnostics (BA/GADx) and Drugs and Diagnostics for Tropical Diseases (DDTD) multi-antigen test Biplex Version C...

Outdoor attractive targeted sugar bait Phase III trials for malaria control in Kenya, Mali, and Zambia: An individual participant data meta-analysis

Attractive targeted sugar baits (ATSB) are a potential new class of vector control tool that act through an “attract and kill” mechanism on mosquitoes. We conducted a meta-analysis using data from three large-scale Phase III trials of the Westham Sarabi v1.2 ATSB (0.11% dinotefur...

Changes in arbovirus risks and responses from 2020 to 2026

Abstract Since 2020, viruses spread by mosquitoes and biting midges have become a larger and less predictable public health challenge. Dengue continues to cause the greatest burden, but chikungunya, Oropouche, and other viruses are re-emerging or spreading into new areas. In this...

Public awareness of alpha-gal syndrome and tick bite prevention practices, United States, Fall 2023

Alpha-gal syndrome (AGS) is a unique non-infectious tickborne disease that can develop after a tick bite. AGS can cause severe allergic symptoms (when patients are exposed to alpha-gal) and be challenging for patients to manage because alpha-gal is found in mammalian meat, dairy,...

The Framework for Policy Decision on the RTS,S/AS01 malaria vaccine: the use of emerging data to inform global policy on the first malaria vaccine

The World Health Organization (WHO)-coordinated Malaria Vaccine Implementation Programme (MVIP) supported pilot introductions of the RTS,S/AS01 malaria vaccine by the ministries of health through the childhood immunization programmes in Ghana, Kenya and Malawi from 2019 through 2...

Competency Shapes Capacity: Strengthening the US Governmental Epidemiology Workforce.

. 2026;116(S5):S436-S445. https://doi.org/10.2105/AJPH.2026.308699).

Contraception Among Women with Selected Autoimmune Diseases in the United States, 2019: A Claims Analysis.

BACKGROUND: We aimed to estimate contraceptive claims prevalence among reproductive-aged women with selected autoimmune diseases compared with those without these conditions in 2019. MATERIALS AND METHODS: Using IBM MarketScan Commercial Claims and Encounters and Multistate Medic...

Phenotypic insecticide resistance in Jamaican Aedes spp. and resistance-associated transcripts in Aedes aegypti

Insecticide resistance in mosquito vectors threatens control of vector-borne diseases across the Caribbean. In Jamaica, resistance in Aedes aegypti has been documented in both urban and rural settings, while susceptibility of other potential vector species and transcriptional res...

Real-world safety data of human papillomavirus vaccines after marketing in Shandong, China, August 2017–October 2025

After the Human papillomavirus (HPV) vaccine was listed for use in China in 2017, it has proven to be a safe and cost-effective method for preventing HPV infection. With the increase in vaccination volume, its safety is becoming increasingly important. The safety data from post-m...

Trends in Parent-Reported Developmental Disabilities: 2019–2024

OBJECTIVES: To study the national prevalence of 5 developmental disabilities in children 3-17 years in the United States between 2019 and 2024 as well as changes in prevalence by selected demographic and socioeconomic characteristics. METHODS: Data come from the National Health I...

A systematic review and individual patient data meta-analysis to determine the effect of primaquine dose on efficacy, tolerability and safety in uncomplicated Plasmodium vivax malaria in Latin America

Background Primaquine is widely used to prevent relapses of Plasmodium vivax malaria, but the optimal dose in Latin America is unknown. We undertook a systematic review and individual patient data meta-analysis to investigate the efficacy, tolerability and safety of different pri...

Validation of a National Pediatric HIV Risk Screening Tool at 31 Health Facilities in Zambia

BACKGROUND: To improve testing efficiency, Zambia introduced a national pediatric human immunodeficiency virus (HIV) Risk Screening Tool (HRST) in 2019. However, concerns about its sensitivity led to its suspension in 2021 pending formal evaluation. We therefore undertook a forma...

A Multistate Investigation of Serious Adverse Events, including Deaths, following Ceftriaxone Injections, September 2024–August 2025

BACKGROUND: Reports of ceftriaxone serious adverse events (SAEs), including deaths, from multiple jurisdictions during December 2024-January 2025 prompted a nationwide investigation to evaluate product safety, characterize SAEs, and assess for changes in baseline adverse event oc...

Estimating state-level chlamydia and gonorrhea incidence and prevalence among women living in the United States during 2019-2023: mathematical modeling analysis

Abstract Background Estimates of chlamydia and gonorrhea prevalence and incidence have typically focused on national-level epidemiology. Disaggregated estimates are useful for local public health decision making. Methods We developed a Bayesian hierarchical modeling framework to...

Streamlined durability monitoring of DuraNet® Plus and Interceptor® G2 insecticide-treated nets in Northern Region, Cameroon: assessment results in two sites from 2022 to 2025

Abstract Background Insecticide-treated nets (ITNs) are a critical vector control and malaria prevention tool. Routine monitoring of ITN physical and chemical durability is key to assessing their performance under real-world conditions. A streamlined ITN durability monitoring met...

Public health benefits of maternal influenza vaccination among pregnant women and infants <6 months in the United States, 2011-2020.

Pregnant women and infants <6 months are at increased risk of influenza-associated complications. Maternal influenza vaccination during pregnancy has a strong safety record and is effective in reducing the risk of illness in these groups. Here, we estimate influenza disease burde...