Cardiff University

Emerging 4D printed biomedical wearable devices

Abstract This article offers a comprehensive overview of the advancements in 4D printed biomedical wearable devices. It begins by discussing various three-dimensional printing methods, exploring their specific advantages and applications in the biomedical field. The article highl...

AI and the clinical blind spot: why psychiatry should be part of the conversation about artificial intelligence and human behaviour

Artificial intelligence (AI) systems that model human behaviour are built on data humans generate about themselves, yet the assumption that this data is reliable remains largely unexamined. Psychiatry's evidence base directly challenges it. Self-report is shaped by cognitive dist...

Resolving Host-Associated Antimicrobial Resistance in Municipal Wastewater Using Hi-C Metagenomics

Conventional wastewater metagenomics enables population-level surveillance of antimicrobial resistance (AMR) but provides limited insight into the bacterial hosts, genomic context, and the mobility of resistance determinants. In this study, we applied high-throughput chromosome c...

Large language models eroding science understanding: an empirical study of ‘malignment’

Abstract Large Language Models (LLMs) increasingly provide scientific information to non-specialist users, yet their linguistic fluency can create an impression of expertise that exceeds their capacity for scientific judgement. This paper experimentally investigates how readily a...

Structural validity and measurement invariance of the WHO-5 Well-Being Index among young adolescents in a family-focused prevention context in Southeastern Europe

Abstract Background The World Health Organization Five Well-Being Index (WHO-5) is a widely used, open-access measure of subjective well-being. However, evidence on its psychometric properties among young adolescents participating in preventive interventions in low- and middle-in...

PROFILING THE MOLECULAR STATE OF THE LIVING BRAIN IN SCHIZOPHRENIA AND ALZHEIMER'S DISEASE USING BRAINGENIE: THE BRAIN GENE EXPRESSION AND NETWORK IMPUTATION ENGINE

In 2005, Professor Ming T. Tsuang and his team published the first blood-based transcriptomic study of a psychiatric disorder in the journal he founded, Neuropsychiatric Genetics. In that pioneering work, Tsuang et al. established the validity of blood-based gene-expression profi...

Avoiding erroneous decisions: evidence, population impact and acceptability of universal mental health interventions in schools – a commentary on Andrews et al.

Foulkes and colleagues argue many ‘universal’ interventions to prevent mental health problems are harmful (‘inflating prevalence’ because they raise awareness of mental health problems, encouraging those without such problems to misinterpret everyday concerns as symptoms of menta...

Power without Capacity? Despotic Centralism, Local Government, and the Contradictions of the English Council Tax Regime

The financing of English local government has become a critical aspect of centre-local relations during a period in which austerity has produced greater pressures on the former. The main means of funding local government is through Council Tax, a system of taxation based on resid...

Design of a nonlinear double-breast single-axis gradient coil with controlled anterior–posterior gradient variation for diffusion-weighted imaging

Abstract Introduction High-performance whole-body gradient systems show promise for breast diffusion-weighted imaging, but their performance is constrained by physiological limits. Although local nonlinear gradient coils can provide stronger gradients while remaining within these...

Tell me what you read, and I will tell you what you remember: Evidence for personalized embeddings in memory modelling

Computational models of memory have achieved considerable success by formalizing how traces are encoded, cued, and retrieved. However, the role that individual linguistic experience plays in shaping representational structure has been relatively understudied. Where the issue has...

Investigation of Dyeing and Fastness Behaviors of Bio-Mordanted Wool Fabric Dyed with Black Carrot Natural Dye

In this study, the coloring of wool fabric samples using a natural dye extracted from black carrots has been investigated using the ultrasonic-assisted method. The natural dye was extracted from black carrots with conventional heating. Before the dyeing process, the samples were...

Deciphering the genomic signatures of climate vulnerability across 77 sheep breeds

Abstract Among domesticated species, sheep ( Ovis aries ) have achieved a wide geographic distribution due to their mobility, rusticity and ability to adapt to diverse environments and climatic conditions. Here, we characterise the genome-wide diversity of >1,000 sheep representi...

Treatment interventions for longstanding and severe eating disorders: an updated systematic review and narrative synthesis

To update the evidence on treatment outcomes for adults with longstanding and severe eating disorders (ED) by reviewing quantitative studies published since 2019 and identifying priorities for future research. Systematic searches were conducted in June 2024 and updated in April 2...

Revisiting the Origins of the ‘Roundhead’ in 1641

Abstract This article revisits the contested origins of the political label ‘Roundhead’ during the English Revolution, challenging the conventional view that the term originated spontaneously during the Westminster tumults of December 1641. While historians have generally relied...

Biologic Therapy in Pregnant Women with Plaque Psoriasis: A Narrative Review of Maternal and Fetal Safety Considerations

Background: Psoriasis in pregnancy is a highly prevalent inflammatory condition worldwide, with patients asking how the disease itself, as well as the medications that they take, would affect the general health of the fetus and the course of pregnancy. Objectives: This narrative...

The Rare dISease Evaluation (RISE) study: a survey-based investigation of medical student experience and knowledge of rare disease in the UK

Abstract Background Rare diseases are a significant public health concern, with over 6,000 diseases identified with an estimated collective point prevalence of 5.6–6.9%. People living with rare disease face numerous challenges within healthcare including prolonged time to diagnos...

Assessing glymphatic role in the association between choroid plexus enlargement and white matter lesions load: The uncertain path through diffusion tensor imaging along the perivascular space (DTI-ALPS)

Background The choroid plexus (CP) is involved in cerebrospinal fluid production, immune surveillance, and brain fluid homeostasis. CP enlargement has been linked to neuroinflammation, glymphatic dysfunction, and white matter lesion (WML) burden, but the mechanisms underlying the...

Flood shelter identification using a mechanics-based approach and triangular fuzzy analytical hierarchy process

Flood events continue to cause substantial damage to people, infrastructure and communities. Effective evacuation planning is essential, and the identification of safe shelters is a key element in protecting people and property. Shelter selection depends on a reliable flood risk...

Common variant contributions to neurodevelopmental risk in orofacial clefts

Abstract Background Children with cleft lip and/or palate (CL/P) experience increased rates of neurodevelopmental difficulties, including ADHD, autism spectrum disorder, and educational challenges. While rare neurodevelopmental copy number variants (ND-CNVs) are enriched in this...

Liking Fast-Food Brands Predicts Poorer Diet Quality, Independent of Perceived Healthiness

Within the theory of planned behavior, ambivalent attitudes (that are simultaneously positive and negative) can weaken the link between attitudes, intentions and behavior. This study examined whether perceived healthiness of fast-food brands would weaken the relationship between...