Cairo University

Addition of low-load blood flow restriction training to conventional physiotherapy improves handgrip strength and function in patients with lateral epicondylitis at the short-term: A single-blind randomized clinical trial

Background Evidence regarding Blood Flow Restriction (BFR) training for the management of lateral epicondylitis (LE) remains limited and conflicting, although BFR has shown potential to improve muscle strength in other musculoskeletal rehabilitation settings. Objective To investi...

Two-dimensional calculations for the novel axial turbo-vapor compressor

Abstract Turbo-vapor compressors (TVCs) are critical for generating vacuum pressure in a novel combined cycle for electricity and freshwater production. This paper presents a new TVC design comprising a single axial compressor rotor directly driving a single axial turbine rotor,...

A novel Arctan-based model: Bayesian analysis, progressive censoring, and practical applications

For modeling and analyzing complex datasets in various scientific fields, probability distributions are crucial. Nevertheless, complex characteristics found in real-world data, like skewness, heavy tails, or high variability, are frequently missed by classical distributions. This...

A novel repurposing opportunity for valsartan: angiotensin II type 1 receptor blockade dampens muscle-to-brain sensitization in fibromyalgia by targeting lncRNA H19/miR-29a-3p, inflammatory mediators, AKT/CREB signaling, neurotrophic factors, and amyloid–Tau pathology

Fibromyalgia (FM) is a debilitating nociplastic pain disorder increasingly recognized to involve skeletal muscle as an active contributor to peripheral nociception and central sensitization rather than a passive target of disease. Although angiotensin II promotes pain signaling t...

GC–MS-based chemometric profiling of volatile oils from Ocimum varieties reveals bioactive markers associated with anti-skin cancer activity

Abstract Skin cancer is the most commonly diagnosed cancer worldwide. Basil oils have been traditionally used for alleviating various diseases. This study investigated the chemical profile and anticancer activity of five basil oils’ varieties (purple, lemon, Italian, Asian, and l...

Systemic oral steroids versus intratympanic steroid injection in idiopathic sudden sensorineural hearing loss: a randomized controlled trial

Abstract Background Idiopathic sudden sensorineural hearing loss (ISSNHL) is characterized by a rapid decline in hearing that impacts three or more frequencies by a minimum of 30 dB and that persists for three days or less, without any discernible cause. This study aims to compar...

Influences of sorghum-based diets on poultry production systems

This review article outlines the different impacts of sorghum supplementation as an effective corn alternative in poultry nutrition, focusing on production performance, carcass traits, gut health, and blood parameters. The cereal grain sorghum, can substitute corn as a growth pro...

Structure property and wear correlations in Al–Ni intermetallic coatings produced by atmospheric plasma spraying

Abstract Atmospheric plasma spraying (APS) is widely employed to fabricate protective coatings for engineering components requiring enhanced wear resistance and thermal stability. This study establishes structure property wear correlations in Al–Ni intermetallic coatings deposite...

Minimally invasive circumferential fixation using TIFI and INFIX for unstable pelvic ring injuries: a prospective evaluation of clinical and radiological outcomes

To evaluate the clinical and radiological outcomes of minimally invasive circumferential fixation using combined trans-iliac internal fixation (TIFI) and anterior internal fixation (INFIX) in unstable pelvic ring injuries. A prospective study was conducted between 2022 and 2023 i...

Phenotypic Diversity in Moricandia nitens (Brassicaceae): An Integrative Study of Sympatric Flower-Color Morphs in Coastal Egypt

Moricandia DC. (Brassicaceae) is a Mediterranean genus of agronomic importance as a co-cenospecies of Brassica L., comprising eight recognized species. During spring 2022, white- and pink-flowered morphs were collected from five sympatric populations at Ras El-Hikma, Mersa-Matruh...

Treatment of hypertrophic scars using fractional CO2 laser alone in comparison with adding botulinium toxin either intalesional injection or assisted drug delivery

Abstract Burns result in hypertrophic scarring, causing functional impairment, cosmetic and psychological concerns. Fractional CO₂ laser and botulinum, have shown promise in treatment. To evaluate the effectiveness of fractional laser treatment alone and combined with botulinum t...

DFT Investigations of Kubas-Type Hydrogen Storage in C₁₉X Heterofullerenes: d-Orbital Preservation Under Substitutional Transition Metal Doping

Hydrogen is a promising clean energy carrier, but safe and efficient solid-state storage remains a major challenge. Here, dispersion-corrected density functional theory (PBE-D3BJ/def2-TZVPD) was employed to investigate C₁₉X heterofullerenes (X = Si, Ge, Ti, V, Ni, and Zr) as hydr...

Enhancing search efficiency in large-scale constrained multi-objective optimization using a decision variable importance matrix

Existing constrained multi-objective evolutionary algorithms (CMOEAs) encounter significant challenges in solving large-scale constrained multi-objective optimization problems (LSCMOPs), as the exponentially increasing search space severely restricts their optimization efficiency...

Compressive Strength and Design Provisions for Continuous Steel Angle Braces in Telecommunication Towers: Stability-Based Approach

Abstract Steel angle towers are commonly used in telecommunication infrastructure due to their structural efficiency and cost-effectiveness. Their performance under horizontal loading depends mainly on the behavior of their cross-bracing angles. When one brace goes into compressi...

BRCA1/2 variant profiling and HPV/HMTV DNA detection in a cohort of Egyptian women with breast cancer

Abstract Breast cancer (BC) is a multifactorial disease influenced by both genetic and environmental factors. Pathogenic variants in BRCA1 and BRCA2 significantly increase hereditary BC risk, while oncogenic viruses such as human Papillomavirus (HPV) and human mammary tumor virus...

Cluster headache care gaps among primary healthcare physicians in the Middle East, North Africa, and Türkiye: a multinational study

Cluster headache is one of the most severely disabling primary headache disorders and is frequently associated with diagnostic delay, inappropriate treatment, disability, and substantial psychosocial burden. Because primary healthcare (PHC) physicians are commonly the first point...

Ethnopharmacological insights into type 2 diabetes management by traditional Moroccan herbal teas: HPLC-MS characterization of phenolic compounds and their related antioxidant and enzyme inhibitory activities

Abstract Background Traditional Moroccan herbal teas are widely consumed and have been traditionally used for managing chronic metabolic disorders, particularly type 2 diabetes mellitus (T2DM). Although these preparations have a long history of ethnomedicinal use, their phenolic...

Oncology nurse navigator core competencies and patient satisfaction

Oncology nurse navigators (ONNs) are increasingly recognized for their vital role in improving the quality of cancer care by supporting patients throughout their treatment journey. In Egypt, nurse navigation implementation remains limited, and empirical evidence examining the rel...

Ensemble transformer-based framework for predicting finger angles

Abstract More than 50% of individuals with upper-limb amputation reject the use of prosthetic devices, primarily due to limitations in functionality, comfort, and intuitive control. Accurate estimation of finger joint angles is a key requirement for proportional prosthetic contro...

XGB-AGMoE: A Validation-Adaptive XGBoost-Anchored Granular Mixture-of-Experts Framework for Multi-Class Intrusion Detection in IoMT WiFi–MQTT Traffic

The Internet of Medical Things (IoMT) environment is based on WiFi and MQTT communication, which results in highly imbalanced intrusion-detection data with a high degree of heterogeneity. In this study, XGB-AGMoE is proposed, a validation-adaptive XGBoost-anchored Granular Mixtur...