Cairo University

The filtration performance of fabrics against particles of viral size: a systematic review

Wearing a mask is part of the comprehensive strategy to suppress transmission of the SARS-CoV-2 virus and respiratory tract infections. Despite available COVID-19 vaccines, wearing a mask has remained one of the simplest and most effective ways. There was, however, little data av...

Hidden hypertension and early cardiac alterations: insights from ambulatory blood pressure monitoring in children and adolescents

Abstract Background Hypertension is increasingly recognized as a significant health concern among children and adolescents, often associated with obesity and lifestyle choices. Early-onset hypertension can elevate the risk of cardiovascular diseases in adulthood, making early det...

Incretins beyond weight and hyperglycemia management: a consensus statement by AASD

Abstract Background The global prevalence of obesity continues to rise, with 3 billion adults projected to be affected by 2030. Recent advances in anti-obesity pharmacotherapy, particularly incretin-based medications, have transformed obesity management. This consensus provides e...

Nano-boosted green coffee bean extract cream for enhanced anti-cellulite topical therapy: A randomized clinical trial

Cellulite is a prevalent cosmetic concern among postpubertal women, and the efficacy of conventional topical therapies remains limited. Green coffee bean extract (GCBE) exhibits antioxidant and lipolytic activities relevant to cellulite management; however, its topical performanc...

Approaches to nonlinear programming problems: Taylor series expansion, RBF surrogate modeling, DOE-based dimensionality reduction, and adaptive domain splitting

<title>Abstract</title> Solving nonlinear constrained optimization problems efficiently remains a challenge. This paper describes a four-component method developed to address these difficulties: Design of Experiments (DOE) screening using L9 and L81 orthogonal arrays to eliminate...

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

BACKGROUND: Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1-2% of patients annually despite adequate therapy. The mechanisms underlying these events rem...

Assessment of anxiety levels and marital relationships among women undergoing infertility treatment: A descriptive observational study

This study aimed to assess anxiety levels and marital relationships among women undergoing infertility treatment. A descriptive observational design was conducted involving 300 infertile women over nine months at Zagazig University Hospital. Data were collected using a Structured...

Associations of screen time and physical activity with motor control, mood, and cognitive states in adolescents following acute high-intensity interval training

Excessive screen time and insufficient physical activity are increasingly common among adolescents and have been linked to adverse physical and psychological health outcomes. This school-based cross-sectional study examined associations between sedentary screen time, physical act...

Role of intraoperative ultrasonography as a method of neuro-navigation in surgical treatment of intracranial hemorrhage

Background: Spontaneous intracranial hemorrhage (ICH), the second most common type of stroke, can be fatal or cause severe disability. A key technical goal while studying the surgical therapy of ICH should be the amount of hematoma evacuation. Multiple challenges are encountered...

Repositioning pentoxifylline via inhalable novasomes for pulmonary fibrosis: from statistical optimization to in-vivo evaluation

Pulmonary fibrosis (PF) represents the final stage of lung injuries, triggered mainly by viral infections. Pentoxifylline (PTX) is a hemorheologic drug that has been recently repurposed for the prophylaxis of PF. Nevertheless, it exhibits low oral bioavailability. This study aims...

ELLS–NSBA three-stage framework for optimal DG/SC placement and EV integration in distribution networks

The growing penetration of distributed generation (DG), shunt capacitors (SC), and electric vehicles (EVs) in distribution networks demands optimal siting strategies that balance operational efficiency and structural resilience. Existing metaheuristic approaches treat every bus a...

Evaluation of relative safety and therapeutic efficacy of antihyperlipidemic drug regimens used alone or in combination in cardiovascular disease: randomized controlled study

Abstract Background Statin monotherapy is a cornerstone of lipid-lowering therapy for reducing low-density lipoprotein cholesterol (LDL-C) and cardiovascular risk in patients with dyslipidemia. However, many patients at moderate-to-high cardiovascular risk fail to achieve recomme...

Evaluation of the new Egyptian undergraduate medical program from the perspectives of faculty and institutional leadership: a nationwide, mixed-method study

Abstract Background In response to global calls for medical education reform, Egypt restructured its national undergraduate medical education program from a 6 + 1 model to a competency-based “5 + 2” model. This reformed program emphasizes early clinical exposure, integration of b...

Comparative evaluation of Saccharomyces, Bacillus, and Lactobacillus as antibiotic alternatives on growth performance, redox balance, and gut microbiota in broilers

Abstract This study evaluated the efficacy of Saccharomyces cerevisiae (SC), Bacillus subtilis (B), Lactobacillus casei (LB), and their combination (Mix) as natural alternatives to antibiotics in broiler nutrition. Liquid cultures were prepared to a density of 10⁸ CFU/mL and exam...

Infectious complications following bispecific antibody or CAR T therapy in adult patients with hematologic malignancies: a retrospective database analysis

T-cell redirection therapies, including bispecific antibodies (BsAbs) and chimeric antigen receptor (CAR) T therapy, have transformed the treatment of relapsed or refractory hematologic malignancies. However, comparative data on infectious complications between these treatments r...

Green stability-indicating RP-HPLC method for simultaneous bioanalysis of tedizolid phosphate and ciprofloxacin in human plasma

Abstract Tedizolid phosphate (TP) and ciprofloxacin (CIP) represent orally effective antibiotics that are often administered in combination for hospitalized patients with complicated or mixed infections, aiming to provide wide antimicrobial coverage. This study describes, for the...

Efficacy and Safety of Baxdrostat for Patients With Uncontrolled or Resistant Hypertension: A Systematic Review and Meta-Analysis

We evaluated the efficacy and safety of baxdrostat in adults with uncontrolled or resistant hypertension. We searched PubMed, Scopus, Web of Science, and Cochrane CENTRAL from inception to January 2026. We included randomized controlled trials that involved hypertension patients...

Sustainable Leadership, Workplace Integration, and Resilience Among Staff Nurses: A Cross-Sectional Correlational Study

Background: Sustainable leadership has emerged as a critical approach for promoting long-term organizational effectiveness and workforce well-being in healthcare settings. However, empirical evidence linking sustainable leadership to workplace integration and resilience among nur...

Digitalization and Innovation in Egyptian Firms: Does Female Ownership and Management matter?

Abstract This paper examines how leadership gender configurations shape digitalisation and innovation in Egyptian manufacturing. Using the 2020/21 Egyptian Industrial Firm Behavior Survey (EIFBS) covering 2,338 firms, we construct a four-category gender variable (female owners an...

One in seven has severe pain: a point-prevalence study of hospitalised patients across Africa

ABSTRACT: Acute pain in hospitalised patients is common, yet African data are scarce. We conducted a prospective point-prevalence study of hospitalised adult patients across Africa to determine acute pain prevalence and severity and investigate associations of pain with critical...