Cairo University

Rabies and rabies prophylaxis in Egypt: a nationwide cross-sectional study that calls for action

BACKGROUND: Rabies is a fatal but preventable viral disease that poses a global health threat, especially in developing countries. Despite the high incidence of animal bites reported annually in Egypt, limited data exist regarding the knowledge, attitudes, and practices (KAP) of...

XGCN-GAT: An Explainable and Robustness-Aware Hybrid Graph Neural Network Framework for Android Malware Detection

The continued growth of the Android ecosystem has been accompanied by an escalating volume of malicious applications, motivating the development of detection methods that are simultaneously accurate, transparent, and resilient to evasion. Graph-based learning has emerged as a pow...

A Novel Weighted Log-Kumaraswamy Distribution: Mathematical Characterization, Statistical Inference, and Reliability Applications

Primary technique: Construction of a new Weighted Log-Kumaraswamy lifetime distribution using the weighted general family of distributions. In this paper, a new three-parameter lifetime model, called the Weighted Log-Kumaraswamy Distribution (WLKD), is proposed by incorporating t...

Dose-Dependent Preservation of Highland Barley Flour Storage Quality by Lycium barbarum Polysaccharide: Evidence from 240-Day Storage Monitoring and Untargeted Lipidomics

Highland barley (hulless barley, Hordeum vulgare L. var. nudum) flour is a nutritionally dense staple of the Qinghai–Tibet Plateau, but its high contents of unsaturated lipids and active endogenous enzymes render it highly susceptible to storage deterioration. Natural polysacchar...

Effect of injectable platelet rich fibrin augmented with vitamin c compared to injectable platelet rich fibrin alone on healing of necrotic mature single rooted teeth with chronic periapical periodontitis following regenerative endodontic therapy (a randomized controlled trial)

OBJECTIVES: To assess the healing potential, postoperative pain and clinical normalcy associated with injectable platelet-rich fibrin combined with Vitamin C in regenerative endodontic procedure using cone-beam computed tomography and two-dimensional radiograph. METHODS: Twenty-e...

Evaluating the effects of metronidazole, metformin, and onion extract on GAPDH activity and nitric oxide production in Blastocystis sp. cultures: a biochemical and therapeutic approach

Abstract Background Blastocystis sp. is a highly prevalent anaerobic intestinal protozoan increasingly associated with gastrointestinal disorders. Its survival within the gut microenvironment depends on metabolic pathways such as glycolysis, where glyceraldehyde-3-phosphate dehyd...

Transcutaneous Vagus Nerve Stimulation Improves Motor Function of Upper Extremity in Adults with Chronic Ischemic Stroke: A Randomized Controlled Trial

BackgroundUpper limb motor dysfunctions are common after stroke affecting daily activities. About 60% of survivors still have impairment despite rehabilitation.ObjectiveTo assess the effect of transcutaneous auricular vagal nerve stimulation (taVNS) on upper limb motor function i...

Understanding Firm Dynamics and Performance Under COVID-19

Abstract We use data from the 2020/21 Egyptian Industrial Firm Behavior Survey (EIFBS) to examine the impact of the COVID-19 crisis on firm dynamics and performance. To gain a deeper understanding, our second objective is to explore potential underlying correlates of firm dynamic...

Redefining Limits: A Clinical Trial on the Safety of Combining Liposuction with Undermining During Abdominoplasty.

OBJECTIVES: In spite of the popularity of liposuction with abdominoplasty, there is little objective evidence to the extent of liposuction and width of undermining that is safe. This study aims to objectively evaluate the safety and aesthetic outcomes of liposuction and extensive...

Reduced contrast volume in coronary CT angiography: effects on coronary attenuation

Abstract Background Coronary CT angiography (CCTA) requires intravenous iodinated contrast to achieve diagnostic intraluminal opacification. Because reducing the contrast volume administered per examination is an exposure-reduction strategy of practical interest, institutions hav...

A chaotropic agent-assisted, AQbD-guided RP-HPLC method for the simultaneous determination of rosuvastatin, atorvastatin, and ezetimibe: a rapid, robust, and green approach

The simultaneous determination of rosuvastatin, atorvastatin, and ezetimibe in pharmaceutical formulations is challenging due to their distinct physicochemical properties. This study details the development and validation of a rapid, robust, and stability-indicating reversed-phas...

The chemical influence of flue gas recirculation in NH3-H2 MILD combustion: an experimental and kinetic investigation

Ammonia is a promising hydrogen carrier with potential in carbon-neutral energy systems. However, its combustion faces the challenges of high NO emissions and inadequate stability. Moderate or Intense Low-oxygen Dilution (MILD) combustion preheats NH 3 , promoting its cracking to...

Gamma Irradiation-Induced Synthesis of Dextrin/N-Vinylpyrrolidone Biohydrogel for High-Efficiency Adsorptive Removal of Nitrofurantoin and Methylene Blue from Aqueous Media

Biomedical pollutants, including pharmaceutical residues such as nitrofurantoin (NF) and medical dyes such as methylene blue (MB), are increasingly detected in surface water and wastewater, posing environmental and health concerns due to their durability and biological activity....

Evaluating the biorational profile of selected insecticides in Spodoptera littoralis: from nutritional disruption and genotoxicity to in silico risk analysis

Abstract Background Spodoptera littoralis is a highly destructive pest that threatens various economically important crops. This study evaluated the sublethal effects of five insecticides (Chlorantraniliprole, thiacloprid, emamectin benzoate, indoxacarb, and Bacillus thuringiensi...

Patient Experiences of Access, Stigma, and Trust and Preferences for Non-Opioid Drug Delivery Systems in Chronic Pain Management

Background/Objectives: Chronic pain is common in Saudi Arabia, where opioid analgesics are prescribed and dispensed within a tightly regulated, electronically monitored controlled-substance framework. Qualitative evidence on how patients experience restrictive access comes almost...

Protective effects of Opoka mineral clay against imidacloprid toxicity in juvenile Nile tilapia ( Oreochromis niloticus ): hematological, biochemical, and histopathological insights

Pesticide contamination poses a significant threat to the sustainability of aquaculture, particularly affecting Nile tilapia (Oreochromis niloticus), a key species for global food security. This study evaluated the protective efficacy of dietary Opoka mineral clay against imidacl...

Health literacy and successful aging among elderly patients at Kasr Alainy Hospital: a cross-sectional comparative study

Abstract Background Population aging and chronic disease burden are increasing in Egypt. Health literacy (HL) may play a key role in promoting successful aging (SA), but evidence is limited. Aim To assess HL and SA and examine their association among elderly patients at Kasr Alai...

Mechanistic attenuation by L-carnitine of trastuzumab-induced downregulation of adenosine monophosphate -activated protein kinase signal in cardiac H9c2 cells

Clinical usefulness of trastuzumab (TZ) is restrained owing to its cardiotoxic effect. This investigation was initiated to evaluate the potential protective impact of carnitine (CARN) against TZ-related cardiac influence; and to uncover the underlining mechanism. Cytotoxic effect...

Egyptian Exporters Under the Lens: Uncovering Competitiveness Challenges

Abstract This paper examines the determinants of export participation among Egyptian manufacturing firms using the 2020/21 Egyptian Industrial Firm Behavior Survey (EIFBS). Against the backdrop of Egypt’s persistent export underperformance and limited upgrading in manufacturing e...

Addition of low-load blood flow restriction training to conventional physiotherapy improves handgrip strength and function in patients with lateral epicondylitis at the short-term: A single-blind randomized clinical trial

Background Evidence regarding Blood Flow Restriction (BFR) training for the management of lateral epicondylitis (LE) remains limited and conflicting, although BFR has shown potential to improve muscle strength in other musculoskeletal rehabilitation settings. Objective To investi...