Bilkent University

Multi-criteria assessment of bio-based construction on circularity, environmental impact and feasibility

Over the past decade, the construction industry has increasingly prioritized climate neutrality. In line with this, the EU Green Deal and its ‘Fit-for-55’ legislative package aim to reduce total emissions by 55% by 2030. A major challenge in achieving this goal is addressing the...

A recurrent neuronal model for the effect of predictions on sensory processes

Predictions, prior knowledge, and expectations strongly influence sensory processing and decision-making, yet the neural mechanisms underlying these effects remain a central question in sensory neuroscience. Although the well-established predictive coding model has gained tractio...

Are arterial and venous procedure-related thromboses the same disease? a clinical and hematological comparative study

Arterial and venous thrombosis are traditionally regarded as pathophysiologically distinct processes, yet procedure-related thrombosis following vascular access offers a controlled setting in which an identical iatrogenic trigger (endothelial injury) precipitates thrombosis in di...

Fibrinogen-to-Albumin, Platelet-to-Albumin, and Creatinine-to-Albumin Ratios in the Assessment of Preeclampsia Severity: A Retrospective Case–Control Study

Background: Preeclampsia (PE) is a multisystem pregnancy disorder associated with endothelial dysfunction, inflammation, and coagulation abnormalities. This study evaluated the fibrinogen-to-albumin ratio (FAR), platelet-to-albumin ratio (PAR), and creatinine-to-albumin ratio (Cr...

The fifth player: Understanding bystander responses to gender-based exclusion in esports.

Children and adolescents evaluate gender-based exclusion by drawing on multiple contextual and individual factors. This pre-registered study examined how excluder intentionality, peer norms, and victim response, shaped bystander judgments and responses to the exclusion of a girl...

Incidental finding on the panoramic radiograph during dental examination: osteochondroma of cervical vertebrae

This report presents a case of an upper cervical osteochondroma incidentally detected on routine dental panoramic radiography. A 43-year-old woman presented with bilateral pain in the posterior teeth of both jaws. Panoramic radiography was obtained for routine dental and radiogra...

Western diet induces MASLD and major transcriptional reprogramming in the liver-gut axis of early zebrafish larvae

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to western diet and sedentary lifestyle. While larval zebrafish are powerful discovery tools, standardized diets inducing early-stage MASLD are lacking. Here, we developed and early-stage zebrafis...

Real-world outcomes of children with first relapsed acute lymphoblastic leukemia treated according to the ALL-IC REL 2016 guideline in Türkiye

Relapsed acute lymphoblastic leukemia (ALL) remains a major challenge in pediatric oncology, particularly where access to modern immunotherapies is limited. This national multicenter study evaluated real-world outcomes of children with first relapsed ALL treated according to the...

Clinical management, antifungal susceptibility, and predictors of 28-day mortality in Candidozyma auris candidemia: a single-center cohort study

Candidozyma auris (Candida auris) candidemia is a serious healthcare-associated infection with substantial mortality and limited treatment options. We retrospectively evaluated adult patients with C. auris candidemia at a tertiary care center between June 2022 and December 2025 t...

Pediatric community-acquired acute kidney injury at a quaternary-care emergency department: clinical outcomes and prognostic determinants

Community-acquired acute kidney injury (CA-AKI) in children is less well characterized than hospital-acquired AKI but may be associated with serious clinical outcomes. This study evaluated the clinical characteristics, etiologic distribution, short-term renal outcomes, and progno...

Fabry Disease Screening in Kidney Transplant Recipients: A Single-Center Retrospective Study

Background: Fabry disease (FD) is an X linked lysosomal storage disorder caused by deficient α galactosidase A (α GAL A) activity, leading to progressive multisystem involvement, including kidney disease. Evidence on FD screening in kidney transplant recipients is limited. We aim...

Ticari İşlerde Faiz Serbestisinin İşlevi, Kapsamı ve Sınırları Üzerine

Bu makale 6102 sayılı Türk Ticaret Kanunu m 8(1) çerçevesinde ticari işlerde faiz serbestisinin işlevi, kapsamı ve sınırlarını incelemektedir. Sözleşme serbestisinin bir görünümü olan faiz oranını belirleme hürriyeti, ticari işlerde yaklaşık bir asırdır uygulanmaktadır. Ticari iş...

Non-Invasive Skin Imaging Techniques for Diagnosing and Monitoring Mycosis Fungoides: A Comprehensive Review

Mycosis fungoides, the most common primary cutaneous T-cell lymphoma, presents notable diagnostic challenges. In its early stages, it may resemble inflammatory dermatoses both clinically and histologically, causing delays in diagnosis. These factors can lead to treatment delays,...

Salvage Autologous Stem Cell Transplantation in Relapsed/Refractory Multiple Myeloma: Long-Term Efficacy and Safety Outcomes from a Single-Center Real-World Cohort

Background: The role of salvage autologous stem cell transplantation (ASCT) in relapsed/refractory multiple myeloma (R/R MM) is being reconsidered in the era of novel immunotherapies. We evaluated the long-term efficacy and safety of salvage ASCT in a real-world single-center coh...

Arthroscopic Free Bone Block Transfer Technique Using Iliac Crest Autograft With Anchor‐Button Fixation for Glenohumeral Instability and Glenoid Bone Loss

Abstract Bone block transfer for the treatment of glenohumeral instability with severe glenoid bone loss or multiple recurrences has grown in popularity in recent years. In this technical note, we described an arthroscopic‐assisted free bone block transfer technique, using a spec...

Superlarge-Bore Versus Large-Bore Aspiration Catheters in Mechanical Thrombectomy: A Multicenter Propensity-Matched Analysis

BACKGROUND AND OBJECTIVES: Aspiration catheters are an integral component of mechanical thrombectomy for acute ischemic stroke (AIS). Following early series demonstrating increasing procedural efficiency and improved outcomes with use of large-bore (LB) aspiration catheters, ther...

ROX index and NEWS2 for 28-day mortality prediction in emergency department patients with acute dyspnea: a prospective observational study

Acute dyspnea is a frequent and high-risk presentation in emergency departments (ED), requiring rapid identification of patients at increased risk of deterioration and mortality. This study aimed to compare the accuracy of the Respiratory Rate–Oxygenation (ROX) index and National...

Safety of patient-facing AI-generated medical advice: a structured clinical evaluation using acute appendicitis scenarios

Abstract Background Patient-facing large language model–based chatbots are increasingly used to seek medical advice and support health-related decision-making. While these tools provide accessible health information, their safety in high-risk, time-sensitive clinical scenarios re...

Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event

BackgroundPatients are at increased risk for recurrent ischemic events after an acute coronary syndrome event. Milvexian, an oral factor XIa inhibitor, may reduce the risk of major adverse clinical events with minimal bleeding risk. MethodsIn this phase 3, randomized, placebo-con...

The Role of HbA1c, CRP/Albumin, and Neutrophil/Lymphocyte Ratio in Predicting Mortality in Geriatric Patients with Diabetic Foot Ulcers

Objectives: This study aimed to evaluate the association between laboratory-based metabolic, inflammatory, and nutritional markers and in-hospital mortality among patients aged 65 years and older with diabetic foot ulcers. Materials and Methods: The retrospective study included 1...