Bernstein Center for Computational Neuroscience Tübingen

High‐Density Magnetomyography With Optical Magnetometers Reveals Spatiotemporal Patterns of Evoked Muscle Activity

ABSTRACT Magnetomyography (MMG) holds great potential as a contactless alternative to electromyography (EMG). However, the spatiotemporal dynamics of the myomagnetic field in vivo remain largely unknown, limiting signal interpretability and hence the use of MMG. Here, the myomagn...

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

BACKGROUND: Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. OBJECTIVES: To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to ide...

Tales of “Good Indian Hair”: Race, Value, and Sensory Contact Zones in Afro‐Asian Delhi

ABSTRACT Hair, as a sociocultural bodily signifier, also becomes, once disembodied, a highly globalized and specialized commodity used for weaves, extensions, wigs and toupees around the globe. “Indian” hair is particularly valued in such commodity chains. Consequently, several m...

Plasticity Dynamics Improves Reservoir Performance on Mixed-Timescale Memory Tasks

Mixed-timescale signals are ubiquitous in natural stimuli and real-world applications, yet they remain challenging to process with recurrent neural networks. Reservoir computing offers an efficient framework for temporal processing, but extending its temporal range typically requ...

Increased firing rates monotonically expand neuronal coding bandwidth

Sensory information is often processed by populations of neurons that vary with respect to their levels of spiking activity. It appears plausible that neurons that fire more often are capable of following faster changes in the input signal than those with lower firing rates. In t...

Lebanese faunal legacy collections uncover 400,000 years of woodland resilience and distinct hominin ecological strategies

Abstract The Levant is a key biogeographic corridor, yet historical instability has limited research creating a polarization toward its southern region. To address this geographical bias, we reassessed three legacy faunal collections from Lebanon: Naame, Nahr Ibrahim, and Ras el-...

Aberrant Expression of Multiple T‐Cell Markers in Primary Cutaneous Follicle Center Lymphoma: A Rare Case Report

ABSTRACT Aberrant expression of T‐cell markers in B‐cell lymphomas is rare and can pose diagnostic challenges. We report a case of a 65‐year‐old man presenting with newly developed scalp nodules. Histopathology revealed nodular lymphoid infiltrates composed of large centrocytes a...

A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer

Abstract Small cell lung cancer (SCLC) is one of the most aggressive malignancies, characterized by rapid metastatic dissemination and poor overall survival. Despite harboring excessive alterations, expectedly resulting in immunogenic neoantigens, patients with SCLC remain largel...

Durable clinical and immunologic response to an off-the-shelf EWSR1–FLI1 peptide vaccine in metastatic Ewing sarcoma

Abstract Ewing sarcoma is a rare, fusion-driven malignancy with poor prognosis in the metastatic setting, for which no established immunotherapeutic treatment is currently available. Fusion breakpoints are rational precision immunotherapy targets, yet clinical evidence of immunog...

An elementary form of agency at planetary-scale

Abstract The claim that climate homeorhesis—non-equilibrium steady-state dynamics that underlie Earth’s long-term habitability—depends on an integrated biosphere–climate system capable of acting on its own is central to debates surrounding the Gaia hypothesis. This paper presents...