Beijing Tian Tan Hospital

Multicenter Privacy‐Preserving Federated Models for Predicting Postoperative Delirium and Acute Kidney Injury in Older Patients

ABSTRACT Postoperative delirium (POD) and acute kidney injury (AKI) are serious complications in older patients undergoing surgery, yet predictive model development is often constrained by single‐center data limitations and privacy concerns that preclude centralized data sharing....

Longitudinal gut microbiome dynamics in neurosurgical ICU patients: Enterococcus expansion as a feature of microbial restructuring

Abstract Background Gut microbiota alterations are commonly observed in critical illness, but their temporal dynamics in neurosurgical ICU patients remain insufficiently characterized. This study aimed to describe postoperative microbial trajectories and their clinical context du...

A retrospective comparative study of chronic subdural hematoma in patients with or without decreased level of consciousness

Abstract Background In this retrospective cross-sectional study, we aimed to investigate the effects of preoperative decreased level of consciousness (DOC) on 6-month outcome and the risk factors that compromised the consciousness at admission in patients with chronic subdural he...

Antioxidant nanozymes for regenerative medicine: mechanisms, design, and applications in tissue repair

Natural antioxidant enzymes play a central role in regulating oxidative stress within living organisms. During tissue repair following injury, these enzymes act synergistically to scavenge excess reactive oxygen species and maintain cellular redox homeostasis, thereby supporting...