Beijing Anzhen Hospital

Predicting left-ventricular recovery and characterizing Cardiorenal risk after Transcatheter aortic valve replacement: A routine-data phenotyping and prediction-model study

Background Ejection fraction (LVEF) underpins risk stratification before transcatheter aortic valve replacement (TAVR), yet it does not indicate whether an impaired ventricle will recover once the stenosis is relieved, or what drives death in high-risk patients. We asked whether...

Handgrip strength and/or Timed Up and Go Test are associated with functional independence and psychological well-being in older women

Abstract Background Handgrip strength (HGS) and Timed Up and Go (TUG) tests are established measures of physical capacity and widely utilized in geriatric assessments. We aimed to assess their independent and combined association with activity of daily living (ADL) and psychologi...

Energy-based devices for enhanced transdermal drug delivery in pathological scars: A review

Although laser-assisted drug delivery (LADD) technology is well established, its clinical application has now expanded to include a broader range of energy-based devices (EBDs). This review aims to evaluate the use of energy-based device-assisted drug delivery (EADD) in the treat...

Association of the Chinese visceral adiposity index with incident cardiovascular disease in cardiovascular-kidney-metabolic syndrome stages 0–3: a nationwide prospective cohort study

Abstract Background Cardiovascular-kidney-metabolic (CKM) syndrome integrates metabolic abnormalities, chronic kidney disease, and cardiovascular disease (CVD), with stages 0–3 representing a critical window for primary prevention. Whether the Chinese visceral adiposity index (CV...

Association of Statin Use With Short- and Long-Term Mortality in Critically Ill Patients With Aortic Stenosis: A Retrospective Cohort Study

Background Statins have not been shown to modify valvular disease progression in relatively stable aortic stenosis populations, but their prognostic relevance during critical illness remains unclear. Methods We conducted a retrospective cohort study using the MIMIC-IV database. A...

Genetic predictive links between oropharyngeal microecology and obstructive sleep apnea syndrome: expanding the perspective of etiology

Background Obstructive sleep apnea syndrome (OSAS), a global public health concern, is linked to oropharyngeal microbiota, but observational studies cannot confirm their causal association.Objective To explore the potential causal relationship between oropharyngeal microecology a...

Intraarterial Thrombolysis: Past, Present, Future

Suboptimal clinical outcomes are common after ischemic stroke with large vessel occlusion despite current reperfusion treatment with intravenous thrombolysis and mechanical thrombectomy. Targeting residual distal arterial and microvascular occlusions with intraarterial thrombolys...

Early postoperative prediction of gastrointestinal bleeding after surgery for acute type A aortic dissection: a five-variable logistic regression model benchmarked against machine learning

Gastrointestinal bleeding is a clinically important complication after emergency surgery for acute type A aortic dissection. Dedicated postoperative risk-stratification tools for this high-risk population remain limited. We aimed to develop and internally validate an early postop...

Impact of sex disparities on laparoscopic adrenalectomy outcomes: a coarsened exact matching study

It is unclear how sex disparities affect surgical outcomes following retroperitoneal laparoscopic adrenalectomy (RLA). Therefore, we studied whether gender could affect RLA outcomes perioperatively. A retrospective study was performed involving consecutive cases underwent unilate...

Comparison of Staged and Concomitant Percutaneous Coronary Intervention in Patients Undergoing Transcatheter Aortic Valve Replacement: A Retrospective Cohort Study

AIM: This study aims to compare the clinical outcomes of concomitant versus staged percutaneous coronary intervention (PCI) in patients with severe aortic valve disease and significant coronary artery stenosis undergoing transcatheter aortic valve replacement (TAVR).METHODS: We r...

Oral anticoagulation therapy in nonagenarian patients with atrial fibrillation: usage patterns, predictors, and in-hospital outcomes from a single-center retrospective study

Abstract Background Atrial fibrillation (AF) is highly prevalent in nonagenarians (≥ 90 years). However, this group is often excluded from clinical trials, leaving limited real-world evidence on oral anticoagulant (OAC) use, safety, and efficacy. This study sought to investigate...

Predictive Value of Imaging Indicators for Disease Progression in Acute Stanford Type B Aortic Intramural Hematoma Without Ulcer-like Lesions

PURPOSE: To investigate the clinical outcomes of acute Stanford type B intramural hematoma (TBIMH) without ulcer-like lesions following medical management and to identify predictors of disease progression. MATERIALS AND METHODS: A retrospective analysis was performed on patients...