Alexandria University

Ovarian Cyst Fluid as a Resource for Diagnostic and Prognostic Biomarker Discovery in Ovarian Lesions

Background/Objectives: Differentiating benign, borderline, and malignant ovarian cystic lesions before surgery remains challenging, and many women undergo operations for lesions that prove benign. Most cystic lesions contain fluid that lies in direct contact with the lesion and f...

In Ovo Folic Acid Injection Modulates Hatchability, Hematobiochemical Profiles, Immune Status, and Intestinal Histomorphology of Day-Old Broiler Chicks

This study evaluated the effects of in ovo folic acid administration on hatchability, physiological profiles, and intestinal development in day-old Cobb broiler chicks. A total of 600 embryonated eggs were assigned to five treatments: an uninjected control, a saline control, and...

Hibiscus sabdariffa protects against fibromyalgia by modulating the neuroinflammation–oxidative stress–microRNA axis

Fibromyalgia (FM) is a chronic syndrome characterized by widespread pain, fatigue, cognitive dysfunction and neuropsychiatric disturbances, associated with dysregulated oxidative stress and neuroinflammation. Emerging evidence suggests that microRNAs guiding these pathways, inclu...

Cluster headache care gaps among primary healthcare physicians in the Middle East, North Africa, and Türkiye: a multinational study

Cluster headache is one of the most severely disabling primary headache disorders and is frequently associated with diagnostic delay, inappropriate treatment, disability, and substantial psychosocial burden. Because primary healthcare (PHC) physicians are commonly the first point...

Green-synthesized copper nanoparticles differentially modulate germination and selected stress-response genes in Phelipanche aegyptiaca

Abstract Egyptian broomrape ( Phelipanche aegyptiaca ) is a devastating parasitic weed requiring eco-friendly control strategies. This in vitro study investigated the effects of green-synthesised copper oxide (CuO) nanoparticles, produced using Anethum graveolens extract, on P. a...

Association between personality traits, dental caries, and oral health-related behaviors among underserved Egyptian adults: a cross-sectional study

Abstract Background The Big Five personality traits comprise five broad dimensions of personality namely openness, conscientiousness, extraversion, agreeableness, and neuroticism which may influence oral health. Examining these influences in underserved communities helps inform t...

Comparative assessment of CBCT and digital radiography in quantifying periapical pathology (in vitro study)

OBJECTIVE: To compare the diagnostic accuracy of phosphor plate-based digital periapical radiography (DPR) and CBCT in quantifying periapical lesions compared to the reference standard. MATERIALS AND METHODS: This in vitro study included 45 premolar teeth with simulated periapica...

Hydrocarbon Contamination Contributes to Increases in Soil Organic Carbon: Impacts on Risk Assessments of Contaminated Land in the UK

In the UK, contaminated land risk assessments using the Contaminated Land Exposure Assessment (CLEA) model rely on soil organic matter (SOM) values to determine acceptable thresholds for contamination caused by anthropogenic pollution for human health. Soil organic carbon (SOC),...

Academic educators’ leadership styles and their associations with student engagement and critical thinking disposition among Saudi health sciences students: a mixed-methods study

Educator leadership behaviors are widely recognized as an important component of the classroom environment and may be associated with student engagement and critical thinking disposition. In health sciences education, these competencies are fundamental to clinical reasoning and e...

Beyond self-reports: the neuro-service quality (NSQ) framework

Purpose The paper is a critical reflection on the prevalence of self-report in the research on the quality of hospitality service and offers a new, neuro-scientifically based framework: neuro-service quality (NSQ). It is intended to solve the validity crisis in conventional surve...

Improving the cryo-resistance of Egyptian buffalo semen via chlorogenic acid and rutin supplementation: molecular docking, antioxidant, and anti-apoptotic pathways

Abstract This study compared the antioxidant effects of chlorogenic acid (CGA) and rutin (RU) supplementation in freezing extenders on the cryo-resistance of buffalo spermatozoa. Over eight weeks, 56 ejaculates were collected from seven fertile buffalo ( Bubalus bubalis ) bulls....

Rethinking satisfaction metrics: from online reviews to holistic experience analytics

Purpose The present study aims to question the trend of relying heavily on online reviews as the primary indicator of customer satisfaction in the hotel industry, exposes the disadvantages of the suggested strategy and suggests a more credible and multifaceted approach as an alte...

Thermocapillary migration of a concentric double emulsion in creeping flow

The thermocapillary migration of a concentric spherical compound droplet suspended in an unbounded immiscible fluid and subjected to a uniform temperature gradient is investigated theoretically. The analysis is carried out in the creeping-flow and conduction-dominated limits, wit...

Recent Horizons in Pyridine-Based Agrochemicals (2020-2026): From Molecular Design to Ecological Safety

Abstract Pyridine derivatives have emerged as indispensable pharmacophoric scaffolds in contemporary agrochemistry, driving breakthroughs across next-generation insecticides, plant growth regulators (PGRs), micronutrient chelators, and biostimulants. This review provides a compre...

Anxiety and mood disorders are associated with greater healthcare and procedural utilization in idiopathic intracranial hypertension

Background and purpose Anxiety and mood disorders (AMD) are common in idiopathic intracranial hypertension (IIH), but their association with procedural treatment and healthcare utilization is unclear. We evaluated utilization among patients with AMD documented before or shortly a...

Efficacy and safety of oncolytic herpes simplex virus therapy in solid tumors: a systematic review and meta-analysis of 38 clinical trials

Abstract Background Oncolytic herpes simplex virus (oHSV) therapy represents a novel immunotherapeutic approach for solid tumors. Despite regulatory approval of talimogene laherparepvec (T-VEC) for advanced melanoma, comprehensive pooled estimates of efficacy and safety across di...

Psychological empowerment and caring behaviours among NICU nurses in the West Bank: a multicentre cross-sectional study

Background: Nurses in neonatal intensive care units (NICUs) face significant emotional and clinical demands affecting caring behaviours. Psychological empowerment is linked to improved nursing outcomes, yet evidence from conflict-affected settings remains limited. Objective: This...

Efficacy of early blood purification on serum inflammatory mediators in severe acute pancreatitis: a systematic review and meta-analysis

Severe acute pancreatitis (SAP) is the most critical form of acute pancreatitis (AP), characterized by a dysregulated systemic inflammatory response that drives early organ failure and mortality. Current management remains mainly supportive. Early blood purification (EBP) has bee...

Knowledge, attitudes, and practices (KAP) toward stroke prevention among hypertensive patients in Egypt: a multicenter cross-sectional study

Abstract Stroke is the second most common cause of death worldwide and represents a major health concern in Egypt. Hypertension is the most important modifiable risk factor for stroke; we aim to assess knowledge, attitudes, and practices (KAP) toward stroke prevention among hyper...

Serum HDGFL2 as a novel biomarker for disease activity in Egyptian patients with rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterized by persistent joint inflammation and tissue damage. The pathogenesis of RA involves complex immune dysregulation, necessitating the identification of reliable biomarkers to a...